Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2

British Journal of Pharmacology

Volumn 171, Issue 7, 2014, Pages 1747-1757

  Bhakkiyalakshmi, Elango ^a   Shalini, Devibalan ^b   Sekar, Thillai Veerapazham ^c   Rajaguru, Palanisamy ^b   Paulmurugan, Ramasamy ^c   Ramkumar, Kunka Mohanram ^a,c  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

^b ANNA UNIVERSITY   (India)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; diabetes; Nrf2; pancreatic beta cells; pterostilbene; streptozotocin

Indexed keywords

CASPASE 3; CATALASE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2; PTEROSTILBENE; STILBENE DERIVATIVE; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BINDING ASSAY; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

APOPTOSIS; DIABETES; NRF2; PANCREATIC BETA CELLS; PTEROSTILBENE; STREPTOZOTOCIN;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; INSULIN-SECRETING CELLS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; SIGNAL TRANSDUCTION; STILBENES; STREPTOZOCIN; TIME FACTORS;

EID: 84908881355     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12577     Document Type: Article

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