Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury

Experimental Neurology

Volumn 202, Issue 1, 2006, Pages 57-66

  Dijkstra, S ^a   Duis, S ^a   Pans, I M ^a   Lankhorst, A J ^a   Hamers, F P T ^a   Veldman, H ^a   Bar P R ^a   Gispen, W H ^a   Joosten, E A J ^b   Geisert Jr , E E ^c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Drug delivery; Gliosis; Inflammation; Neuroprotection; Spinal cord injury; Tetraspanins; Therapeutic antibodies

Indexed keywords

ANTIBODY; CD81 ANTIBODY; CD81 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CONTUSION; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; GLIOSIS; HISTOLOGY; INFLAMMATION; LOCOMOTION; MICROGLIA; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCAR FORMATION; SPINAL CORD INJURY;

ANIMALS; ANTIBODIES; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; FEMALE; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NEUROPEPTIDES; PSYCHOMOTOR PERFORMANCE; RATS; RATS, WISTAR; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; TIME FACTORS;

EID: 33748427477     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2006.05.011     Document Type: Article

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