메뉴 건너뛰기




Volumn 19, Issue 1, 2011, Pages 16-43

Anti-neuroinflammatory and neurotrophic effects of combined therapy with annexin II and Reg-2 on injured spinal cord

Author keywords

Annexin II; Neuroprotective effects; Reg 2 protein; Spinal cord injury; White matter sparing

Indexed keywords

LIPOCORTIN 2; PROTEIN; REGENERATION GENE PROTEIN 2; UNCLASSIFIED DRUG;

EID: 79957664140     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000324272     Document Type: Article
Times cited : (15)

References (54)
  • 1
    • 0028955068 scopus 로고
    • The annexins: Specific markers of midline structures and sensory neurons in the developing murine central nervous system
    • Hamre KM, Chepenik KP, Goldowitz D: The annexins: Specific markers of midline structures and sensory neurons in the developing murine central nervous system. J Comp Neurol 1995; 352: 421-435.
    • (1995) J Comp Neurol , vol.352 , pp. 421-435
    • Hamre, K.M.1    Chepenik, K.P.2    Goldowitz, D.3
  • 2
    • 0029875402 scopus 로고    scopus 로고
    • Differential expression of annexins I-VI in the rat dorsal root ganglia and spinal cord
    • DOI 10.1002/(SICI)1096-9861(199 60506)368:3<356::AID-CNE3>3.0.CO;2- 4
    • Naciff JM, Kaetzel MA, Behbehani MM, Dedman JR: Differential expression of annexins I-VI in the rat dorsal root ganglia and spinal cord. J Comp Neurol 1996; 368: 356-370. (Pubitemid 26131662)
    • (1996) Journal of Comparative Neurology , vol.368 , Issue.3 , pp. 356-370
    • Naciff, J.M.1    Kaetzel, M.A.2    Behbehani, M.M.3    Dedman, J.R.4
  • 4
    • 0027451058 scopus 로고
    • Lipocortin 1 (annexin 1) immunoreactivity in the cervical spinal cord of Lewis rats with acute experimental allergic encephalomyelitis
    • DOI 10.1016/0022-510X(93)90127-K
    • Elderfield AJ, Bolton C, Flower RJ: Lipocortins 1 (annexin I) immunoreactivity in the spinal cord of Lewis rats with acute experimental allergic encephalomyelitis. J Neurol Sci 1993; 119: 146-153. (Pubitemid 23343052)
    • (1993) Journal of the Neurological Sciences , vol.119 , Issue.2 , pp. 146-153
    • Elderfield, A.-J.1    Bolton, C.2    Flower, R.J.3
  • 5
    • 0028230177 scopus 로고
    • Lipocortin-1: Cellular mechanisms and clinical relevance
    • DOI 10.1016/0165-6147(94)90281-X
    • Flower RJ, Rothwell NJ: Lipocortin-1: Cellular mechanisms and clinical relevance. Trends Pharmacol Sci 1994; 15: 71-76. (Pubitemid 24086941)
    • (1994) Trends in Pharmacological Sciences , vol.15 , Issue.3 , pp. 71-76
    • Flower, R.J.1    Rothwell, N.J.2
  • 6
    • 0028349621 scopus 로고
    • Lipocortin-derived peptides
    • Perretti M: Lipocortin-derived peptides. Biochem Pharmacol 1994; 47: 931-938. (Pubitemid 24103823)
    • (1994) Biochemical Pharmacology , vol.47 , Issue.6 , pp. 931-938
    • Perretti, M.1
  • 7
    • 0028324464 scopus 로고
    • Annexins: The problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins
    • Raynal P, Pollard HB: Annexins: The problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins. Biochim Biophys Acta 1994; 1197: 63-93.
    • (1994) Biochim Biophys Acta , vol.1197 , pp. 63-93
    • Raynal, P.1    Pollard, H.B.2
  • 8
    • 0030775075 scopus 로고    scopus 로고
    • Annexin gene structures and molecular evolutionary genetics
    • DOI 10.1007/s000180050064
    • Morgan RO, Fernandez MP: Annexin gene structures and molecular evolutionary genetics. Cell Mol Life Sci 1997; 53: 508-515. (Pubitemid 27374491)
    • (1997) Cellular and Molecular Life Sciences , vol.53 , Issue.6 , pp. 508-515
    • Morgan, R.O.1    Fernandez, M.P.2
  • 11
    • 0024847419 scopus 로고
    • A purified lipocortin shares the anti-inflammatory effect of glucocorticosteroids in vivo in mice
    • Errasfa M, Russo-Marie F: A purified lipocortin shares the anti-inflammatory effect of glucocorticosteroids in vivo in mice. Br J Pharmacol 1989; 97: 1051-1058. (Pubitemid 20051917)
    • (1989) British Journal of Pharmacology , vol.97 , Issue.4 , pp. 1051-1058
    • Errasfa, M.1    Russo-Marie, F.2
  • 12
    • 0027379886 scopus 로고
    • Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil- dependent edema in the mouse: A qualitative comparison with an anti-CD11b monoclonal antibody
    • Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ: Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil- dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody. J Immunol 1993; 151: 4306-4314. (Pubitemid 23298764)
    • (1993) Journal of Immunology , vol.151 , Issue.8 , pp. 4306-4314
    • Perretti, M.1    Ahluwalia, A.2    Harris, J.G.3    Goulding, N.J.4    Flower, R.J.5
  • 13
    • 4444317633 scopus 로고    scopus 로고
    • Differential gene expression after complete spinal cord transection in adult rats: An analysis focused on a subchronic post-injury stage
    • DOI 10.1016/j.neuroscience.2004.07.008, PII S0306452204005780
    • Zhang KH, Xiao HS, Lu PH, Shi J, Li GD, Wang YT, Han S, Zhang FX, Lu YJ, Zhang X, Xu XM: Different gene expression after complete spinal cord transection in adult rats: An analysis focused on a subchronic post-injury stage. Neuroscience 2004; 128: 375-388. (Pubitemid 39200484)
    • (2004) Neuroscience , vol.128 , Issue.2 , pp. 375-388
    • Zhang, K.-H.1    Xiao, H.-S.2    Lu, P.-H.3    Shi, J.4    Li, G.-D.5    Wang, Y.-T.6    Han, S.7    Zhang, F.-X.8    Lu, Y.-J.9    Zhang, X.10    Xu, X.-M.11
  • 14
    • 3242742080 scopus 로고    scopus 로고
    • Upregulation of annexins I, II, and V after traumatic spinal cord injury in adult rats
    • DOI 10.1002/jnr.20167
    • Liu N, Han S, Lu PH, Xu XM: Upregulation of annexins I, II and V following traumatic spinal cord injury in adult rats. J Neurosci Res 2004; 77: 391-401. (Pubitemid 38970983)
    • (2004) Journal of Neuroscience Research , vol.77 , Issue.3 , pp. 391-401
    • Liu, N.1    Han, S.2    Lu, P.-H.3    Xu, X.-M.4
  • 16
    • 0030222498 scopus 로고    scopus 로고
    • Roles of phospholipases A 2 in brain cell and tissue injury associated with ischemia and excitotoxicity
    • Bonventre JV: Roles of phospholipases A 2 in brain cell and tissue injury associated with ischemia and excitotoxicity. J Lipid Mediat Cell Signal 1997; 14: 15-23.
    • (1997) J Lipid Mediat Cell Signal , vol.14 , pp. 15-23
    • Bonventre, J.V.1
  • 18
    • 0028219296 scopus 로고
    • Neurotrophic effects of annexin V on cultured neurons from embryonic rat brain
    • DOI 10.1016/0304-3940(94)90604-1
    • Takei N, Ohsawa K, Imai Y, Nakao H, Iwasaki A, Kohsaka S: Neurotrophic effects of annexin V on cultured neurons from embryonic rat brain. Neurosci Lett 1994; 171: 59-62. (Pubitemid 24142089)
    • (1994) Neuroscience Letters , vol.171 , Issue.1-2 , pp. 59-62
    • Takei, N.1    Ohsawa, K.2    Imaia, Y.3    Nakao, H.4    Iwasaki, A.5    Kohsaka, S.6
  • 19
    • 0032544384 scopus 로고    scopus 로고
    • Neurotrophic action of lipocortin 1 derived from astrocytes on cultured rat cortical neurons
    • DOI 10.1016/S0169-328X(98)00163-6, PII S0169328X98001636
    • Mizuno H, Asai K, Fujita K, Uemura K, Wada Y, Moriyama A, Ogawa H, Kimura S, Kato T: Neurotrophic action of lipocortin 1 derived from astrocytes on cultured rat cortical neurons. Brain Res Mol Brain Res 1998; 60: 28-39. (Pubitemid 28433192)
    • (1998) Molecular Brain Research , vol.60 , Issue.1 , pp. 28-39
    • Mizuno, H.1    Asai, K.2    Fujita, K.3    Uemura, K.4    Wada, Y.5    Moriyama, A.6    Ogawa, H.7    Kimura, S.8    Kato, T.9
  • 20
    • 34948894950 scopus 로고    scopus 로고
    • Annexin A1 reduces inflammatory reaction and tissue damage through inhibition of phospholipase A2 activation in adult rats following spinal cord injury
    • DOI 10.1097/nen.0b013e3181567d59, PII 0000507220071000000007
    • Liu NK, Zhang YP, Han S, Pei J, Xu LY, Lu PH, Shields CB, Xu XM: Annexin A1 reduces inflammatory reaction and tissue damage through inhibition of phospholipase A 2 activation in adult rats following spinal cord injury. J Neuropathol Exp Neurol 2007; 66: 932-943. (Pubitemid 47530832)
    • (2007) Journal of Neuropathology and Experimental Neurology , vol.66 , Issue.10 , pp. 932-943
    • Liu, N.-K.1    Zhang, Y.P.2    Han, S.3    Pei, J.4    Xu, L.Y.5    Lu, P.-H.6    Shields, C.B.7    Xu, X.-M.8
  • 21
    • 0026334074 scopus 로고
    • Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis
    • Iovanna J, Orelle B, Keim V, Dagorn JC: Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis. J Biol Chem 1991; 266: 24664-24669. (Pubitemid 21908993)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.36 , pp. 24664-24669
    • Iovanna, J.1    Orelle, B.2    Keim, V.3    Dagorn, J.-C.4
  • 22
    • 0027074133 scopus 로고
    • Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases
    • Orelle B, Keim V, Masciotra L, Dagorn JC, Iovanna JL: Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. J Clin Invest 1992; 90: 2284-2291. (Pubitemid 23010043)
    • (1992) Journal of Clinical Investigation , vol.90 , Issue.6 , pp. 2284-2291
    • Orelle, B.1    Keim, V.2    Masciotra, L.3    Dagorn, J.-C.4    Iovanna, J.-L.5
  • 23
    • 0031946284 scopus 로고    scopus 로고
    • The pancreatitis-associated protein is induced by free radicals in AR4- 2J cells and confers cell resistance to apoptosis
    • DOI 10.1016/S0016-5085(98)70595-5
    • Ortiz EM, Dusetti NJ, Vasseur S, Malka D, Bödeker H, Dagorn JC, Iovanna JL: The pancreatitis- associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis. Gastroenterology 1998; 114: 808-816. (Pubitemid 28160416)
    • (1998) Gastroenterology , vol.114 , Issue.4 I , pp. 808-816
    • Ortiz, E.M.1    Dusetti, N.J.2    Vasseur, S.3    Malka, D.4    Bodeker, H.5    Dagorn J.-, C.6    Iovanna, J.L.7
  • 24
    • 0031472412 scopus 로고    scopus 로고
    • A Schwann cell mitogen accompanying regeneration of motor neurons
    • DOI 10.1038/37615
    • Livesey FJ, O'Brien JA, Li M, Smith AG, Murphy LJ, Hunt SP: A Schwann cell mitogen accompanying regeneration of motor neurons. Nature 1997; 390: 614-618. (Pubitemid 28016196)
    • (1997) Nature , vol.390 , Issue.6660 , pp. 614-618
    • Livesey, F.J.1    O'Brien, J.A.2    Li, M.3    Smith, A.G.4    Murphy, L.J.5    Hunt, S.P.6
  • 25
    • 0025163324 scopus 로고
    • Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain
    • De la Monte SM, Ozturk M, Wands JR: Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain. J Clin Invest 1990; 86: 1004-1013. (Pubitemid 20327395)
    • (1990) Journal of Clinical Investigation , vol.86 , Issue.3 , pp. 1004-1013
    • De La Monte, S.M.1    Ozturk, M.2    Wands, J.R.3
  • 27
    • 0036759657 scopus 로고    scopus 로고
    • Dynamic pattern of Reg-2 expression in rat sensory neurons after peripheral nerve injury
    • Averill S, Davis DR, Shortland PJ, Priestley JV, Hunt SP: Dynamic pattern of reg-2 expression in rat sensory neurons after peripheral nerve injury. J Neurosci 2002; 22: 7493-7501. (Pubitemid 35386350)
    • (2002) Journal of Neuroscience , vol.22 , Issue.17 , pp. 7493-7501
    • Averill, S.1    Davis, D.R.2    Shortland, P.J.3    Priestley, J.V.4    Hunt, S.P.5
  • 29
  • 30
    • 2442462117 scopus 로고    scopus 로고
    • Effects of annexins II and V on survival of neurons and astrocytes in vitro
    • Han S, Zhang KH, Lu PH, Xu XM: Effects of annexins II and V on the survival of neurons and astrocytes in vitro. Acta Pharmacol Sin 2004; 25: 602-610. (Pubitemid 38620684)
    • (2004) Acta Pharmacologica Sinica , vol.25 , Issue.5 , pp. 602-610
    • Han, S.1    Zhang, K.-H.2    Lu, P.-H.3    Xu, X.-M.4
  • 31
    • 49049114995 scopus 로고    scopus 로고
    • Small-molecule protein tyrosine phosphatase inhibition as a neuroprotective treatment after spinal cord injury in adult rats
    • Nakashima S, Arnold SA, Mahoney ET, Sithu SD, Zhang YP, D'Souza SE, Shields CB, Hagg T: Small-molecule protein tyrosine phosphatase inhibition as a neuroprotective treatment after spinal cord injury in adult rats. J Neurosci 2008; 28: 7293-7303.
    • (2008) J Neurosci , vol.28 , pp. 7293-7303
    • Nakashima, S.1    Arnold, S.A.2    Mahoney, E.T.3    Sithu, S.D.4    Zhang, Y.P.5    D'Souza, S.E.6    Shields, C.B.7    Hagg, T.8
  • 32
    • 0346094444 scopus 로고    scopus 로고
    • The effects of ciliary neurotrophic factor on neurological function and glial activity following contusive spinal cord injury in the rats
    • DOI 10.1016/j.brainres.2003.10.036
    • Ye J, Cao L, Cui R, Huang A, Yan Z, Lu C, He C: The effects of ciliary neurotrophic factor on neurological function and glial activity following contusive spinal cord injury in the rats. Brain Res 2004; 997: 30-39. (Pubitemid 38058532)
    • (2004) Brain Research , vol.997 , Issue.1 , pp. 30-39
    • Ye, J.1    Cao, L.2    Cui, R.3    Huang, A.4    Yan, Z.5    Lu, C.6    He, C.7
  • 34
    • 0030157694 scopus 로고    scopus 로고
    • Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
    • DOI 10.1006/exnr.1996.0098
    • Basso DM, Beattie MS, Bresnahan JC: Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 1996; 139: 244-256. (Pubitemid 26228093)
    • (1996) Experimental Neurology , vol.139 , Issue.2 , pp. 244-256
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 35
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso DM, Beattie M, Bresnahan JC: A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 1995; 12: 1-21.
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.2    Bresnahan, J.C.3
  • 36
    • 0014942484 scopus 로고
    • Selective staining of degenerating axons in the central nervous system by a simplified silver method: Spinal cord projections to external cuneate and inferior olivary nuclei in the cat
    • Eager RP: Selective staining of degenerating axons in the central nervous system by a simplified silver method: Spinal cord projections to external cuneate and inferior olivary nuclei in the cat. Brain Res 1970; 22: 137-141.
    • (1970) Brain Res , vol.22 , pp. 137-141
    • Eager, R.P.1
  • 37
    • 1842419475 scopus 로고    scopus 로고
    • Degenerative and regenerative mechanisms governing spinal cord injury
    • DOI 10.1016/j.nbd.2003.11.015, PII S0969996103002523
    • Profyris C, Cheema SS, Zang D, Azari MF, Boyle K, Petratos S: Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol Dis 2004; 15: 415-436. (Pubitemid 38429958)
    • (2004) Neurobiology of Disease , vol.15 , Issue.3 , pp. 415-436
    • Profyris, C.1    Cheema, S.S.2    Zang, D.3    Azari, M.F.4    Boyle, K.5    Petratos, S.6
  • 38
    • 0037017477 scopus 로고    scopus 로고
    • Current developments in spinal cord injury research
    • Carlson GD, Gorden C: Current developments in spinal cord injury research. Spine J 2002; 2: 116-128.
    • (2002) Spine J , vol.2 , pp. 116-128
    • Carlson, G.D.1    Gorden, C.2
  • 39
    • 0041700229 scopus 로고    scopus 로고
    • Repair of chronic spinal cord injury
    • Houle JD, Tessler A: Repair of chronic spinal cord injury. Exp Neurol 2003; 82: 247-260.
    • (2003) Exp Neurol , vol.82 , pp. 247-260
    • Houle, J.D.1    Tessler, A.2
  • 40
    • 38749086493 scopus 로고    scopus 로고
    • Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury
    • DOI 10.1016/j.expneurol.2007.06.009, PII S0014488607002518
    • Donnelly DJ, Popovich PG: Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol 2008; 209: 378-388. (Pubitemid 351181428)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 378-388
    • Donnelly, D.J.1    Popovich, P.G.2
  • 41
    • 0030695396 scopus 로고    scopus 로고
    • Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats
    • DOI 10.1002/(SICI)1097-4547(199 71201)50:5<798::AID-JNR16>3.0.CO;2- Y
    • Shuman SL, Bresnahan JC, Beattie MS: Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J Neurosci Res 1997; 50: 798-808. (Pubitemid 27518276)
    • (1997) Journal of Neuroscience Research , vol.50 , Issue.5 , pp. 798-808
    • Shuman, S.L.1    Bresnahan, J.C.2    Beattie, M.S.3
  • 42
    • 0032838089 scopus 로고    scopus 로고
    • Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury
    • DOI 10.1006/exnr.1999.7118
    • Popovich PG, Guan Z, Wei P, Huitinga I, van Rooijen N, Stokes BT: Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol 1999; 158: 351-365. (Pubitemid 29382826)
    • (1999) Experimental Neurology , vol.158 , Issue.2 , pp. 351-365
    • Popovich, P.G.1    Guan, Z.2    Wei, P.3    Huitinga, I.4    Van Rooijen, N.5    Stokes, B.T.6
  • 44
    • 2142821430 scopus 로고    scopus 로고
    • Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function
    • DOI 10.1523/JNEUROSCI.5343-03.2004
    • Gris D, Marsh DR, Oatway MA, Chen Y, Hamilton EF, Dekaban GA, Weaver LC: Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function. J Neurosci 2004; 24: 4043-4051. (Pubitemid 38544230)
    • (2004) Journal of Neuroscience , vol.24 , Issue.16 , pp. 4043-4051
    • Gris, D.1    Marsh, D.R.2    Oatway, M.A.3    Chen, Y.4    Hamilton, E.F.5    Dekaban, G.A.6    Weaver, L.C.7
  • 45
    • 74249106986 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression
    • Inukai T, Uchida K, Nakajima H, Yayama T, Kobayashi S, Mwaka ES, Guerrero AR, Baba H: Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression. Spine 2009; 34: 2848-2857.
    • (2009) Spine , vol.34 , pp. 2848-2857
    • Inukai, T.1    Uchida, K.2    Nakajima, H.3    Yayama, T.4    Kobayashi, S.5    Mwaka, E.S.6    Guerrero, A.R.7    Baba, H.8
  • 49
    • 0031015075 scopus 로고    scopus 로고
    • Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys
    • DOI 10.1038/nm0197-73
    • Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS: Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med 1997; 3: 73-76. (Pubitemid 27019144)
    • (1997) Nature Medicine , vol.3 , Issue.1 , pp. 73-76
    • Crowe, M.J.1    Bresnahan, J.C.2    Shuman, S.L.3    Masters, J.N.4    Beattie, M.S.5
  • 50
    • 16944363478 scopus 로고    scopus 로고
    • Neuronal and glial apoptosis after traumatic spinal cord injury
    • Liu XZ, Xu XM, Hu R, Du C, Zhang SX, Mc- Donald JW, Dong HX, Wu YJ, Fan GS, Jacquin MF, Hsu CY, Choi DW: Neuronal and glial apoptosis after traumatic spinal cord injury. J Neurosci 1997; 17: 5395-5406. (Pubitemid 27300306)
    • (1997) Journal of Neuroscience , vol.17 , Issue.14 , pp. 5395-5406
    • Choi, D.W.1
  • 51
    • 0031452352 scopus 로고    scopus 로고
    • Quantitative analysis of acute axonal pathology in experimental spinal cord contusion
    • Rosenberg LJ, Wrathall JR: Quantitative analysis of acute axonal pathology in experimental spinal cord contusion. J Neurotrauma 1997; 14: 823-838. (Pubitemid 28007567)
    • (1997) Journal of Neurotrauma , vol.14 , Issue.11 , pp. 823-838
    • Rosenberg, L.J.1    Wrathall, J.R.2
  • 52
    • 0035068206 scopus 로고    scopus 로고
    • Delayed glial cell death following Wallerian degeneration in white matter tracts after spinal cord dorsal column cordotomy in adult rats
    • DOI 10.1006/exnr.2000.7622
    • Warden P, Bamber NI, Li H, Esposito A, Ahmad KA, Hsu CY, Xu XM: Delayed glial cell death following Wallerian degeneration in white matter tracts after spinal cord dorsal column cordotomy in adult rats. Exp Neurol 2001; 168: 213-224. (Pubitemid 32289757)
    • (2001) Experimental Neurology , vol.168 , Issue.2 , pp. 213-224
    • Warden, P.1    Bamber, N.I.2    Li, H.3    Esposito, A.4    Ahmad, K.A.5    Hsu, C.Y.6    Xu, X.M.7
  • 53
    • 0031467240 scopus 로고    scopus 로고
    • BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal regeneration
    • Kobayashi NR, Fan DP, Giehl KM, Bedard AM, Wiegand SJ, Tetzlaff W: BDNF and NT- 4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP- 43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration. J Neurosci 1997; 17: 9583-9595. (Pubitemid 28006402)
    • (1997) Journal of Neuroscience , vol.17 , Issue.24 , pp. 9583-9595
    • Kobayashi, N.R.1    Fan, D.-P.2    Giehl, K.M.3    Bedard, A.M.4    Wiegand, S.J.5    Tetzlaff, W.6
  • 54
    • 67349252363 scopus 로고    scopus 로고
    • Recombinant ciliary neurotrophic factor promotes nerve regeneration and induces gene expression in silicon tube-bridged transected sciatic nerves in adult rats
    • Xu JJ, Chen EY, Lu CL, He C: Recombinant ciliary neurotrophic factor promotes nerve regeneration and induces gene expression in silicon tube-bridged transected sciatic nerves in adult rats. J Clin Neurosci 2009; 16: 812-817.
    • (2009) J Clin Neurosci , vol.16 , pp. 812-817
    • Xu, J.J.1    Chen, E.Y.2    Lu, C.L.3    He, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.