TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1

Journal of Clinical Investigation

Volumn 124, Issue 11, 2014, Pages 4989-5001

  Gao, Guofeng ^a   Wang, Weiwei ^a   Tadagavadi, Raghu K ^a   Briley, Nicole E ^a   Love, Michael I ^a   Miller, Barbara A ^a   Reeves, W Brian ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; CASPASE 3; CASPASE 9; CLUSTERIN; MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2; HYDROGEN PEROXIDE; NEUROPEPTIDE; RAC1 PROTEIN, MOUSE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HEMATOPOIETIC CELL; HISTOLOGY; HYPOXIA; IN VIVO STUDY; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REPERFUSION INJURY; ACUTE KIDNEY FAILURE; ANIMAL; C57BL MOUSE; ENZYMOLOGY; EPITHELIUM CELL; HEK293 CELL LINE; HUMAN; ISCHEMIA; KIDNEY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; VASCULARIZATION;

ACUTE KIDNEY INJURY; ANIMALS; APOPTOSIS; CELL MEMBRANE; ENZYME ACTIVATION; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; HYDROGEN PEROXIDE; ISCHEMIA; KIDNEY; KIDNEY TUBULES, PROXIMAL; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROPEPTIDES; OXIDATIVE STRESS; PROTEIN TRANSPORT; RAC1 GTP-BINDING PROTEIN; REPERFUSION INJURY; TRPM CATION CHANNELS;

EID: 84908635178     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76042     Document Type: Article

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