Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels

Kidney International

Volumn 49, Issue 2, 1996, Pages 449-460

  Venkatachalam, Manjeri A ^a   Weinberg, Joel M ^b   Patel, Yogendra ^b   Saikumar, Pothana ^b   Dong, Zheng ^b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AVERMECTIN B1 A; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CYANOTRIPHENYLBORON; GLYCINE; NIFLUMIC ACID; STRYCHNINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DOG; KIDNEY EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0030042591     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.64     Document Type: Article

References (43)

1. WEINBERG JM, DAVIS JA, ABARZUA M, RAJAN T: Cytoprotective effects of glycine and glutathione against hypoxic injury to rat tubules. J Clin Invest 80:1446-1454, 1987
2. BAINES AD, SHAIKH N, HO P: Mechanisms of perfused kidney cytoprotection by alanine and glycine. Am J Physiol 259:F80-F87, 1990
3. WEINBERG JM, VENKATACHALAM MA, GARZA-QUINTERO R, ROESER NF, DAVIS JA: Structural requirements for protection by small amino-acids against hypoxic injury in kidney proximal tubules. FASEB J 4:3347-3354, 1990
4. HEYMANN SN, SPOKES K, ROSEN S, EPSTEIN FH: Mechanisms of glycine protection in hypoxic injury: Analogies with glycine receptor. Kidney Int 42:41-45, 1992
5. MANDEL LJ, SCHNELLMANN RG, JACOBS WR: Intracellular glutathione in the protection from anoxic injury in renal proximal tubules. J Clin Invest 85:316-324, 1990
6. DICKSON RC, BRONK SF, GORES GJ: Mechanisms of protection by glycine against lethal hepatocellular injury during ATP depletion. Gastroenterology 102:2098-2107, 1992
7. ALMEIDA ARP, WETZELS JFM, BUNNACHAK D, BURKE TJ, CHAIMOWITZ C, HAMMOND WS, SCHRIER RW: Acute phosphate depletion and in vitro rat proximal tubule injury: Protection by glycine and acidosis. Kidney Int 41:1494-1500, 1992
8. WEINBERG JM, DAVIS JA, ROESER NF, VENKATACHALAM MA: Role of increased cytosolic free calcium in the pathogenesis or rabbit proximal tubule cell injury and protection by glycine or acidosis. J Clin Invest 87:581-590, 1991
9. GARZA-QUINTERO R, WEINBERG JM, ORTEGA-LOPEZ J, DAVIS JA, VENKATACHALAM MA: Conservation of structure in ATP-depleted proximal tubules: Role of calcium, polyphosphoinositides, and glycine. Am J Physiol 265:F605-F623, 1993
10. WEINBERG JM, VENKATACHALAM MA, ROESER NF, DAVIS JA, VARANI J, JOHNSON KJ: Amino acid protection of cultured kidney tubule cells against calcium ionophore-induced lethal cell injury. Lab Invest 65:671-678, 1991
11. WANG W-N, WETZELS JFM, ARNOLD PE, BURKE TJ, SCHRIER RW: Strychnine protects against hypoxic injury in freshly isolated rat renal proximal tubules. (abstract) J Am Soc Nephrol 2:656, 1991
12. ALEO MD, SCHNELLMANN RG: The neurotoxicants strychnine and bicuculline protect renal proximal tubules from mitochondrial inhibitor-induced cell death. Life Sci 51:1783-1787, 1992
13. BETZ H, BECKER C-M: The mammalian glycine receptor: Biology and structure of a neuronal chloride channel protein. Neurochem Int 13:137-146, 1988
14. MILLER GW, SCHNELLMANN RG: Cytoprotection by inhibition of chloride channels: The mechanism of action of glycine and strychnine. Life Sci 53:1211-1215, 1993
15. MILLER GW, SCHNELLMANN RG: A putative cytoprotective receptor in the kidney: Relation to the neuronal strychnine-sensitive glycine receptor. Life Sci 55:27-34, 1994
16. REEVES WB: Cytoprotective effects of Cl-channel blockers in hypoxic injury. (abstract) J Am Soc Nephrol 5:907, 1994
17. 2+ and glycine on lipid breakdown and death of ATP-depleted MDCK cells. Kidney Int 48:118-128, 1995
18. SMITH PK, KROHN RI, HERMANSON GT, MALLIA AK, GARTNER FH, PROVENZANO MD, FUJIMOTO EK, GOEKE NM, OLSON BS, KLENK DC: Measurement of protein using bicinchoninic acid. Anal Biochem 150:76-85, 1985
19. JONES KH, SENET JA: An improved method to determine cell viability by simultaneous staining with fluorescein diacetate - propidium iodide. J Histochem Cytochem 33:77-79, 1985
20. FISHER MH: Recent progress in avermectin research, in Pest Control with Enhanced Environmental Safety, edited by SO DUKE, MENN JJ, PLIMMER JR, American Chemical Society. ACS Symposium Series #524, 1993, pp 169-182
21. FISHER MH, MROZIK H: Chemistry, in Ivemectin and Abamectin, edited by CAMPBELL WC, New York. Springer-Verlag, 1989, pp 1-23
22. CARLOS J, MARVIZÓN G, VÁZQUEZ J, CALVO MG, MAYOR F JR, GÓMEZ AR, VALDIVIESO F, BENAVIDES J: The glycine receptor: Pharmacological studies and mathematical modeling of the allosteric interaction between the glycine- and strychnine-binding sites. Mol Pharmacol 30:590-597, 1986
23. 1a. Eur J Pharmacol 99:269-277, 1984
24. RUNDSTROM N, SCHMIEDEN V, BETZ H, BORMANN J, LANGOSCH: Cyanotriphenylborate Subtype-specific blacker of glycine receptor chloride channels. Proc Natl Acad Sci USA 91:8950-8954, 1994
25. BETZ H: Ligand-gated ion channels in the brain: The amino acid receptor superfamily. Neuron 5:383-392, 1990
26. BELZER FO, SOUTHARD JH: Principles of solid organ preservation by cold storage. Transplantation 45:673-676, 1988
27. CABANTCHIK ZI, GREGER R: Chemical probes for anion transporters of mammalian cell membranes. Am J Physiol 262:C803-C827, 1992
28. WEINBERG JM, VARANI J, JOHNSON KJ, ROESER NF, DAME MK, DAVIS AJ, VENKATACHALAM MA: Protection of humam umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury. Am J Pathol 140:457-471, 1992
29. GREGER R: Chloride channel blockers, in Methods in Enzymology (vol 191), New York, Academic Press, 1990, pp 793-810
30. COUSIN JL, MOTAIS R: Inhibition of anion permeability by amphiphilic compounds in human red cell: Evidence for an interaction of niflumic acid with the Band 3 protein. J Membr Biol 46:125-153, 1979
31. MACKNIGHT ADC, LEAF A: Regulation of cellular volume, in Physiology of Membrane Disorders (2nd ed), edited by ANDREOLI TE, HOFFMAN JF, FANESTIL DD, SCHULTZ SG. New York, Plenum Medical, 1986, pp 311-328
32. KREISBERG JI, MILLS JW, JARRELL JA, RABITO CA, LEAF A: Protection of cultured renal tubular epithelial cells from anoxic cell swelling and cell death. Proc Natl Acad Sci USA 77:5445-5447, 1980
33. CARINI R, AUTELLI R, BELLOMO G, DIANZANI MU, ALBANO E: Sodium-mediated cell swelling is associated with irreversible damage in isolated hepatocytes exposed to hypoxia or mitochondrial toxins. Biochem Biophys Res Commun 206:180-185, 1995
34. SEEMAN P: The membrane actions of anesthetics and tranquilizers. Pharmacol Rev 24:583-655, 1972
35. HILLE B: Ionic Channels of Excitable Membranes. Sunderland, Sinauer, 1992
36. HAMILL OP, BORMANN J, SAKMANN B: Activation of multiple-conductance state chloride channels in spinal neurons by glycine and GABA. Nature 305:805-808, 1983
37. CULLY DF, VASSLIATIS DK, LIU KK, PARESS PS, VAN DER PLOEG LHT, SCHAEFFER JM, ARENA JP: Cloning of an Avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans. Nature 371:707-711, 1994
38. 1a. J Biochem Toxicol 6:283-292, 1991
39. SCHONROCK B, BORMANN J: Activation of Cl-channels by Avermectin in rat cultured hippocampal neurons. Naunyn Schmiedebergs Arch Pharmacol 348:628-632, 1993
40. KUHSE J, BECKER CM, SCHMIEDEN V, HOCH W, PRIBILLA I, LANGOSCH D, MALOSIO ML, MUNTZ M, BETZ H: Heterogeneity of the inhibitory glycine receptor. Ann NY Acad Sci 625:129-135, 1991
41. SCHMIEDEN V, KUHSE J, BETZ H: Mutation of glycine receptor subunit creates beta-alanine receptor responsive to GABA. Science 262:256-258, 1993
42. RUDDY GL, IWAMOTO T, TOMICH JM, MONTAL M: Synthetic peptides and four-helix bundle proteins as model systems for the pore-forming structure of channel proteins. II. Transmembrane segment M2 of the brain glycine receptor is a plausible candidate for the pore-lining structure. J Biol Chem 268:14608-14615, 1993
43. PLOTKIN M, KOJIMA R, GULLANS SR: Colocalization of GABA transporter and receptor in rat kidney. (abstract) J Am Soc Nephrol 5:318, 1994