Pharmacological comparison of novel synthetic fenamate analogues with econazole and 2-APB on the inhibition of TRPM2 channels

British Journal of Pharmacology

Volumn 167, Issue 6, 2012, Pages 1232-1243

  Chen, Gui Lan ^a   Zeng, Bo ^a   Eastmond, Sarah ^b   Elsenussi, Sandra E ^b   Boa, Andrew N ^b   Xu, Shang Zhong ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b UNIVERSITY OF HULL   (United Kingdom)

Author keywords

2 aminoethoxydiphenyl borate; calcium channel; econazole; fenamate analogues; non steroidal anti inflammatory drugs; TRPM2

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE RIBOSE; CALCIUM ION; DICLOFENAC; ECONAZOLE; FENAMIC ACID DERIVATIVE; FLUFENAMIC ACID; HYDROGEN PEROXIDE; INDOMETACIN; MEFENAMIC ACID; NIFLUMIC ACID; TETRACYCLINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2;

ARTICLE; CALCIUM TRANSPORT; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; ELECTROPHYSIOLOGY; FLUOROMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; INHIBITION KINETICS; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BORON COMPOUNDS; CALCIUM; ECONAZOLE; FENAMATES; HEK293 CELLS; HUMANS; TRPM CATION CHANNELS;

EID: 84867833564     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02058.x     Document Type: Article

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