TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 4, 2006, Pages

  Zhang, Wenyi ^a   Hirschler Laszkiewicz, Iwona ^a   Tong, Qin ^a   Conrad, Kathleen ^a   Sun, Shao Cong ^a   Penn, Linda ^b   Barber, Dwayne L ^b   Stahl, Richard ^c   Carey, David J ^c   Cheung, Joseph Y ^a   Miller, Barbara A ^a,d  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c WEIS CENTER FOR RESEARCH   (United States)

^d PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Oxidative stress; Tumor necrosis factor

Indexed keywords

CALCIUM ION; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL M2 CHANNEL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME DEGRADATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS INFECTION; RNA INTERFERENCE;

ALTERNATIVE SPLICING; ANIMALS; CALCIUM; CASPASES; CELL DEATH; CELL LINE; COLLAGEN TYPE XI; ENZYME ACTIVATION; HEMATOPOIETIC STEM CELLS; HUMANS; HYDROGEN PEROXIDE; OXIDANTS; OXIDATIVE STRESS; PROTEIN ISOFORMS; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; TRPM CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33646415942     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00205.2005     Document Type: Article

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