Morphological and biochemical alterations activated by antitumor clerodane diterpenes

Chemico-Biological Interactions

Volumn 222, Issue , 2014, Pages 112-125

  Ferreira, Paulo Michel Pinheiro ^a   Militão, Gardenia Carmen Gadelha ^b   Lima, Daisy Jereissati Barbosa ^c   Costa, Nagilla Daniela De Jesus ^a   Machado, Kátia Da Conceição ^a   Santos, André Gonzaga Dos ^d   Cavalheiro, Alberto José ^d   Bolzani, Vanderlan Da Silva ^d   Silva, Dulce Helena Siqueira ^d   Pessoa, Cláudia ^c  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^c FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^d SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Antiproliferative action; Apoptosis; Casearia sylvestris; Cytotoxicity; Human cells; Murine cells

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CLERODANE DERIVATIVE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; 1-(ACETYLOXY)-3,5,6,6A,7,8,9,10-OCTAHYDRO-10-HYDROXY-7,8-DIMETHYL-7-(3-METHYLPENTA-2,4-DIEN-1-YL)NAPHTHO(1,8A-C)FURAN-3,5-DIYL DIBUTANOATE; ANTINEOPLASTIC AGENT; CASEARGREWIIN F; CASEARIN B; CASEARIN D; CASPASE; DITERPENE;

ADULT; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST TUMOR; CASEARIA SYLVESTRIS; CELL MEMBRANE; CELL STRUCTURE; CELL VACUOLE; CELLULAR PARAMETERS; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOPLASM; CYTOPLASMIC VACUOLATION; DNA FRAGMENTATION; DNA SYNTHESIS; DRUG CYTOTOXICITY; DRUG EXPOSURE; DRUG ISOLATION; ENZYME ACTIVATION; FEMALE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HL 60 CELL LINE; IMMUNOCYTOCHEMISTRY; INCUBATION TIME; KARYORRHEXIS; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MOUSE; MTT ASSAY; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SALICACEAE; SARCOMA 180; SKIN TUMOR; ANIMAL; CASEARIA; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; HL-60 CELL LINE; HUMAN; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; PLANT LEAF; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASEARIA; CASPASES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; DITERPENES; DITERPENES, CLERODANE; DNA FRAGMENTATION; FEMALE; HL-60 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PHOSPHATIDYLSERINES; PLANT LEAVES; REACTIVE OXYGEN SPECIES; SARCOMA 180;

EID: 84908570218     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.10.015     Document Type: Article

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