Investigation of extrinsic and intrinsic apoptosis pathways of new clerodane diterpenoids in human prostate cancer PC-3 cells

European Journal of Pharmacology

Volumn 503, Issue 1-3, 2004, Pages 17-24

  Huang, Dong Ming ^a   Shen, Ya Ching ^b   Wu, Chi ^a   Huang, Yao Ting ^a   Kung, Fan Lu ^a   Teng, Che Ming ^a   Guh, Jih Hwa ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Bcl 2 family member protein; Caseamembrin; Casearia membranacea; Caspase; Clerodane diterpene

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; CASEAMEMBRIN A; CASEAMEMBRIN B; CASEAMEMBRIN C; CASEAMEMBRIN D; CASEAMEMBRIN E; CASEAMEMBRIN F; CASPASE 3; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CLERODANE DERIVATIVE; DITERPENOID; FAS LIGAND; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN BID; PROTEIN MCL 1; SULFORHODAMINE B; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CASEARIA; CASEARIA MEMBRANACEA; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; NICK END LABELING; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY;

APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; COLORING AGENTS; DITERPENES; DITERPENES, CLERODANE; ENZYME ACTIVATION; FAS LIGAND PROTEIN; GENES, BCL-2; HUMANS; IN SITU NICK-END LABELING; MALE; MEMBRANE GLYCOPROTEINS; NEOPLASM PROTEINS; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; RHODAMINES; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

EID: 7444265768     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.09.040     Document Type: Article

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