In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa

Pharmaceutical Biology

Volumn 50, Issue 12, 2012, Pages 1479-1487

  Militão, Gardenia C G ^a   Dantas, Ivana N F ^b   Ferreira, Paulo Michel P ^c   Alves, Ana Paula N N ^b   Chaves, Davina C ^d   Monte, Francisco José Q ^b   Pessoa, Cláudia ^b   Odorico De Moraes, Manoel ^b   Costa Lotufo, Letícia V ^b  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^c FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^d FEDERAL INSTITUTE OF EDUCATION   (Brazil)

Author keywords

Antitumor activity; HL60; Sarcoma 180

Indexed keywords

2BETA,2BETA,16ALPHA,20,25 PENTAHYDROXY 22 OXOCUCURBITA 5 EN; CUCURBITACIN; DNA; DOXORUBICIN; FLUOROURACIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CAYAPONIA RACEMOSA; CELL DISRUPTION; CELL MEMBRANE; CELL VACUOLE; CELL VIABILITY; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CUCURBITACEAE; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG STRUCTURE; EOSINOPHILIA; HUMAN; HUMAN CELL; IC 50; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; MALE; MONOTHERAPY; MOUSE; NONHUMAN; SARCOMA 180; SPLEEN WEIGHT;

ADOLESCENT; ADULT; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CUCURBITACEAE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FLUOROURACIL; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; LEUKEMIA, PROMYELOCYTIC, ACUTE; LEUKOCYTES, MONONUCLEAR; MICE; PLANTS, MEDICINAL; SARCOMA 180; TIME FACTORS; TRITERPENES; TUMOR BURDEN; YOUNG ADULT;

CAYAPONIA RACEMOSA; CUCURBITACEAE;

EID: 84869418256     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2012.684691     Document Type: Article

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