Larvicidal activity of the water extract of Moringa oleifera seeds against Aedes aegypti and its toxicity upon laboratory animals

Anais da Academia Brasileira de Ciencias

Volumn 81, Issue 2, 2009, Pages 207-216

  Ferreira, Paulo M P ^a   Carvalho, Ana F U ^a   Farias, Davi F ^a   Cariolano, Nara G ^a   Melo, Vânia M M ^a   Queiroz, Maria G R ^a   Martins, Alice M C ^a   Machado Neto, Joaquim G ^b  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Aedes aegypti; Daphnia magna; Larvicidal activity; Moringa oleifera seeds; Toxicity

Indexed keywords

AEDES AEGYPTI; ANIMALIA; DAPHNIA; DAPHNIA MAGNA; DAPHNIIDAE; MORINGA OLEIFERA; MUS; RATTUS;

EID: 67649854056     PISSN: 00013765     EISSN: 16782690     Source Type: Journal    
DOI: 10.1590/S0001-37652009000200007     Document Type: Article

References (58)

1. Ali GH, El-Taweel GE and Ali MA. 2004. The cytotoxicity and antimicrobial efficiency of Moringa oleifera seeds extracts. Intern J Environ Studies 61: 699-708.
2. AOAC - ASSOCIATION OF OFFICIAL ANALYTICAL CHEMISTS. 1990. Official Methods of Analysis of the Association of Official Analytical Chemists. Arlington: The Association, 1278 p.
3. Arauco LRR, Cruz C and Machado-Neto JG. 2005. Efeito da presença de sedimento na toxicidade aguda do sulfato de cobre e do triclorfon para três espécies de Daphnia. Pesticidas: Rev Ecotox Meio Amb 15: 55-64.
4. Berger MR, Habs M, Jahn SAA and Schmahl D. 1984. Toxicological assessment of seeds from Moringa oleifera and Moringa stenopetala, two highly efficient primary coagulants for domestic water treatment of tropical raw waters. East Afr Med J 61: 712-716.
5. Bharali R, Tabassum J and Azad MR. 2003. Chemomodulatory effect of Moringa oleifera Lam. on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pac J Cancer Prev 4: 131-139.
6. Broin M, Santaella C, Cuine S, Kokou K, Peltier G and JoëT T. 2002. Flocculent activity of a recombinant protein from Moringa oleifera Lam. seeds. Appl Microbiol Biotechnol 60: 114-119.
7. Brown AWA. 1986. Inseticide resistance in mosquitoes: a pragmate review. J Am Mosq Control Assoc 2: 123-139.
8. Cárceres A, Saraiva A, Rizzio S, Zabala L, De Leon E and Navy F. 1992. Pharmacological properties of Moringa oleifera. 2: Screening for antispasmodic, anti-inflammatory and diuretic activity. J Ethnopharmacol 36: 233-237.
9. Carvalho AFFU, Melo VMM, Craveiro AA, Machado MIL, Bantim MB and Rabelo EF. 2003. Larvicidal Activity of the Essencial Oil from Lippia sidoides Cham. agaisnt Aedes aegypti Linn. Mem Inst Osw Cruz 98: 569-571.
10. Chumark P, Khunawat P, Sanvarinda Y, Phornchi-Rasilp S, Morales NP, Phivthongngam L, Rata-Nachamnong P, Srisawat S and Pongrapeeporn KS. 2008. The in vitro and ex vivo antioxidant properties, hypolipidaemic and antiatherosclerotic activities of water extract of Moringa oleifera Lam. leaves. J Ethnopharmacol 116: 439-446.
11. Consoli RAGB and Oliveira RL. 1994. Principais Mosquitos de Importância Sanitária no Brasil. Rio de Janeiro: Fiocruz, 225 p.
12. Chuang PH, Lee CW, Chou JY, Murugan M, Shieh BJ and Chen HM. 2007. Anti-fungal activity of crude extracts and essential oil of Moringa oleifera Lam. Bioresour Technol 98: 232-236.
13. EEC DIRECTIVE OF 1986. Council Directive of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes (86/609/EEC).
14. Fakurazi S, Ithinin H and Gaudar UNL. 2008. Moringa oleifera Lam prevents acetaminophen induced liver injury through restoration of glutathione level. Food Chem Toxicol 46: 2611-2615.
15. Farias DF, Brasil ICF, Ferreira PMP and Carvalho AFFU. 2004. Potencialidade da vagem de Moringa oleifera Lam. como cama de animais de laboratório. Rev Univ Rural 24: 201-202.
16. Ferreira PMP. 2004. Atividade Larvicida do Extrato Aquoso de Moringa oleifera Lamarck contra Aedes aegypti Linnaeus: Identificação Parcial e Caracterização Toxi-colo ́gica do Princípio Ativo. Universidade Federal do Ceará, Departamento de Biologia, 70 p.
17. Ferreira PMP, Carvalho AFFU, Sousa DF, Maga-Lhães JF, Martins AR, Martins AMC and Queiroz MGR. 2007. Water extract of Moringa oleifera seeds: a toxicological approach. REPM 1: 45-57.
18. Ferreira PMP, Farias DF, Oliveira JTA and Carvalho AFFU. 2008. Moringa oleifera: Bioactive compounds and nutritional potential. Rev Nutr 21: 431-437.
19. Gassenschmidt U, Jany KD, Tauscher B and Nier-Bergall H. 1995. Isolation and caracterization of a flocculating protein from Moringa oleifera Lam. Biochim Biophys Acta 1243: 477-481.
20. Geervani P and Devi A. 1981. Influence of protein and fat on utilization of carotene from drumstick (Moringa oleifera) leaves. Indian J Med Res 74: 548-553.
21. Gerdes C. 1997. Como limpar e tratar água suja com sementes de Moringa oleifera, Centro de Fortaleza: Centro de Pesquisa e Assessoria, 18 p.
22. Ghebremichael KA, Gunaratna KR, Henriksson H, Brumer H and Dalhammar G. 2005. Simple purification and activity assay of the coagulant protein from Moringa oleifera seed. Water Res 39: 2338-2344.
23. Grabow WOK, Slabert JL, Morgan WSG and Jahn SAA. 1985. Toxicity and mutagenicity evaluation of water coagulated with Moringa oleifera seed preparations using fish, protozoan, bacterial, coliphage, enzyme, and Ames Salmonella assays. Water SA 11: 9-14.
24. Gubler DJ. 1998. Dengue and Dengue Hemorrhagic Fever. Clin Microbiol Rev 11: 480-496.
25. Guevara A P, Vargas C, Sakurai H, Fujiwara Y, Hashimoto K, Maoka T, Kozuka M, Ito Y, Tokuda H and Nishino H. 1999. An antitumor promoter from Moringa oleifera Lam. Mutation Res 440: 181-188.
26. Gupta R, Kannan GM, Sharma M and Flora SJS. 2005. Therapeutic effects of Moringa oleifera on arsenicinduced toxicity in rats. Environ Toxicol Pharmacol 20: 456-464.
27. Halstead SB. 2007. Dengue. Lancet 370: 1644-1652.
28. 50 values in bioassays. Environ Sci Technol 7: 114-119.
29. Hodge HC and Sterner JH. 1944. Tabulation of toxicity classes. Am Ind Hyg Assoc 10: 94-97.
30. Imboden JB. 1988. The regulation of intracellular signals during lymphocyte activation. Immunol Today 9: 17-18.
31. Iqbal S and Bhanger MI. 2006. Effect of season and production location on antioxidant activity of Moringa oleifera leaves grown in Pakistan. J Food Comp Anal 19: 544-551.
32. Jahn SAA. 1988. Using Moringa seeds as coagulants in developing countries. J Am Water Works Assoc 90: 43-50.
33. Karalliedde LD, Edwards P and Marris TC. 2003. Variables influencing the toxic response to organophosphates in humans. Food Chem Toxicol 41: 1-13.
34. Kumar V, Abbas AK, Fausto N, Robbins SL and Cotran RS. 2004. Pathology Basis of Disease. China: WB Saunders, 1592 p.
35. Litchfield JJT and Wilcoxon FA. 1949. A simplified method for evaluation of dose-effect experiments. J Pharmacol Exp Ther 96: 99-103.
36. Madsen M, Achlundt J and Omer EF. 1987. Effect of water coagulation by seeds of Moringa oleifera on bacterial concentrations. J Trop Med Hyg 90: 101-109.
37. Makkar HPS and Becker K. 1997. Nutrients and antiquality factors in different morphological parts of the Moringa oleifera tree. J Agric Sci 128: 311-322.
38. Mallevialle J, Bruchet A and Fiessinger F. 1984. How safe are organic polymers in water treatment. JAWWA 76: 431-436.
39. Martyn CN, Barker DJP, Osmond C, Harris EC, Edwardson JA and Lacey RF. 1989. Geographical relation between Alzheimer's disease and aluminum in drinking water. Lancet 1: 59-62.
40. Mazzari MB and Georghiou GP. 1995. Characterization of resistance to organophosphate, carbamate, and pyrethroid insecticides in field populations of Aedes aegypti from Venezuela. J Am Mosq Control Assoc 11: 315-322.
41. Morton JF. 1991. The horseradish tree, Moringa pterygosperma (Moringaceae) - A boon to arid lands? Econ Bot 45: 318-333.
42. Ndabigengesere A, Narasiah KS and Talbot BG. 1995. Active agents and mechanism of coagulation of turbid waters using Moringa oleifera. Water Res 29: 703-710.
43. Ndabigengesere A and Narasiah KS. 1998. Quality of water treated by coagulation using Moringa oleifera seeds. Water Res 32: 781-791.
44. OECD - ORGANIZATION FOR ECONOMIC CO-OPERATION and DEVELOPMENT. 2004. Guidelines for Testing of Chemicals. Guideline 202: Daphnia sp. Acute Immobilisation Test. Paris, France, p. 260-275.
45. Omena MC, Navarro DMAF, Paula JE, Luna JS, Fer-Reira DE Lima MR and Sant'Ana AEG. 2007. Larvicidal activities against Aedes aegypti of some Brazilian medicinal plants. Bioresour Technol 98: 2549-2556.
46. Oliveira JTA, Silveira SB, Vasconcelos IM, Cava-Da BS and Moreira RA. 1999. Compositional and nutritional attributes of seeds from the multiple purpose tree Moringa oleifera Lamarck. J Sci Food Agric 79: 815-820.
47. Ramachandran C, Peter KV and Gopalakrishnan PK. 1980. Drumstick (Moringa oleifera): a multipurpose Indian vegetable. Econ Bot 34: 276-283.
48. Rangaswani S and Sankarasubramian S. 1946. Chemical components of the flowers of Moringa pterygosperma. Curr Sci 5: 316-320.
49. Ruckmani K, Kavimani S, Anandan R and Jayakar B. 1998. Effect of Moringa oleifera Lam on paracetamolinduced hepatotoxicity. Indian J Pharm Sci 60: 33-35.
50. Santos AFS, Argolo ACC, Coelho LCBB and Paiva PMG. 2005. Detection of water soluble lectin and antioxidant component from Moringa oleifera seeds. Water Res 39: 975-980.
51. SESA - SECRETARIA DE SAÚDE DO ESTADO DO CEARÁ. 2008. Informe Semanal de Dengue. Fortaleza: Núcleo de Vigilância Epidemiológica, Governo do Estado do Ceará, 10 p.
52. Siddhuraju P and Becker K. 2003. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumsticks tree (Moringa oleifera Lam.) leaves. J Agric Food Chem 51: 44-55.
53. Tatarazako N and Oda S. 2007. The water flea Daphnia magna (Crustacea, cladocera) as a test species for screening and evaluation of chemicals with endocrine disrupting effects on crustaceans. Ecotoxicol 16: 197-203.
54. Thangam TS and Kathiresan K. 1991. Mosquito larvicidal effect of seaweed extracts. Bot Mar 34: 433-435.
55. Waynforth BH. 1980. Injection Techniques: Experimental and Surgical Techniques in the Rat. London: Academic Press, 61 p.
56. WHO - WORLD HEALTH ORGANIZATION. 1999. Prevention and Control of Dengue and Dengue Haemorrhagic Fever, No 29. Comprehensive Guidelines, New Delhi, India, 134 p.
57. WHO - WORLD HEALTH ORGANIZATION. 2005. Guidelines for Laboratory and Field Testing of Mosquito Larvicides. Geneva, Switzerland, 41 p.
58. Zuckere. 1985. Standard evaluation procedure - Acute toxicity test for freshwater fish. Washington: USEPA 540/9-85-006, 17 p.