Dextromethorphan mediated bitter taste receptor activation in the pulmonary circuit causes vasoconstriction

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Upadhyaya, Jasbir D ^a   Singh, Nisha ^a   Sikarwar, Anurag S ^a   Chakraborty, Raja ^a   Pydi, Sai P ^a   Bhullar, Rajinder P ^a   Dakshinamurti, Shyamala ^a,b   Chelikani, Prashen ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b Manitoba Institute of Child Health   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BITTER TASTE RECEPTOR; BITTER TASTE RECEPTOR 1; BITTER TASTE RECEPTOR 10; BITTER TASTE RECEPTOR 13; BITTER TASTE RECEPTOR 14; BITTER TASTE RECEPTOR 16; BITTER TASTE RECEPTOR 3; BITTER TASTE RECEPTOR 38; BITTER TASTE RECEPTOR 39; BITTER TASTE RECEPTOR 4; BITTER TASTE RECEPTOR 40; BITTER TASTE RECEPTOR 41; BITTER TASTE RECEPTOR 42; BITTER TASTE RECEPTOR 43; BITTER TASTE RECEPTOR 44; BITTER TASTE RECEPTOR 45; BITTER TASTE RECEPTOR 46; BITTER TASTE RECEPTOR 47; BITTER TASTE RECEPTOR 48; BITTER TASTE RECEPTOR 49; BITTER TASTE RECEPTOR 5; BITTER TASTE RECEPTOR 50; BITTER TASTE RECEPTOR 7; BITTER TASTE RECEPTOR 8; BITTER TASTE RECEPTOR 9; DEXTROMETHORPHAN; G PROTEIN COUPLED RECEPTOR; MICRORNA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; INOSITOL 1,4,5 TRISPHOSPHATE; MESSENGER RNA; MYOSIN LIGHT CHAIN; SUPEROXIDE; TASTE RECEPTORS, TYPE 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BITTER TASTE; BLOOD VESSEL TONE; CONTROLLED STUDY; DEFENSE MECHANISM; ENZYME ACTIVATION; ENZYME SYNTHESIS; GENE SILENCING; LUNG VASOCONSTRICTION; MOLECULAR IMAGING; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY ARTERY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; SMOOTH MUSCLE FIBER; SWINE; ANIMAL; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IN VITRO STUDY; LUNG; METABOLISM; MYOGRAPHY; PATHOLOGY; PHOSPHORYLATION; PIG; TASTE; VASCULARIZATION; VASOCONSTRICTION;

ANIMALS; DEXTROMETHORPHAN; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; IN VITRO TECHNIQUES; INOSITOL 1,4,5-TRISPHOSPHATE; LUNG; MYOCYTES, SMOOTH MUSCLE; MYOGRAPHY; MYOSIN LIGHT CHAINS; PHOSPHORYLATION; PULMONARY ARTERY; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPEROXIDES; SUS SCROFA; TASTE; VASOCONSTRICTION;

EID: 84908428707     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110373     Document Type: Article

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