Hypoxic neonatal pulmonary arterial myocytes are sensitized to ROS-generated 8-isoprostane

Free Radical Biology and Medicine

Volumn 48, Issue 7, 2010, Pages 882-894

  Gong, Y ^a   Yi, M ^a   Fediuk, J ^a   Lizotte, P P ^a   Dakshinamurti, S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Free radicals; Hypoxia; Isoprostane; Persistent pulmonary hypertension of the newborn; Superoxide dismutase; Thromboxane receptor

Indexed keywords

8 ISOPROSTANE; ADENYLATE CYCLASE; CALCIUM; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; MACROGOL; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; OXYGEN; PEROXIDE; PEROXYNITRITE; PROSTANOID; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THROMBOXANE RECEPTOR; UBIQUINOL CYTOCHROME C REDUCTASE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HYPOXIA; IN VITRO STUDY; INCUBATION TIME; INTERNALIZATION; MUSCLE CELL; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY HYPERTENSION; RECEPTOR BINDING; SENSITIZATION; SIGNAL TRANSDUCTION; SWINE; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ADENYLATE CYCLASE; CALCIUM SIGNALING; CELL HYPOXIA; CELLS, CULTURED; DINOPROST; ELECTRON TRANSPORT COMPLEX III; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INFANT, NEWBORN; MITOCHONDRIA; MYOCYTES, SMOOTH MUSCLE; PERSISTENT FETAL CIRCULATION SYNDROME; PROTEIN BINDING; PULMONARY ARTERY; REACTIVE OXYGEN SPECIES; RECEPTORS, THROMBOXANE; SUPEROXIDE DISMUTASE; VASOCONSTRICTION;

SUS;

EID: 77549087367     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.01.009     Document Type: Article

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