High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression

American Journal of Physiology - Endocrinology and Metabolism

Volumn 307, Issue 9, 2014, Pages E764-E772

  White, Amanda T ^a   Philp, Andrew ^c   Fridolfsson, Heidi N ^a,b   Schilling, Jan M ^a,b   Murphy, Anne N ^a   Hamilton, D Lee ^d   McCurdy, Carrie E ^e   Patel, Hemal H ^a,b   Schenk, Simon ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF STIRLING   (United Kingdom)

^e UNIVERSITY OF OREGON   (United States)

Author keywords

High fat diet; Insulin resistance; SIRT1; Skeletal muscle

Indexed keywords

GLUCOSE; INSULIN; SIRTUIN 1; SIRT1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; BODY WEIGHT; CALORIMETRY; CONTROLLED STUDY; ENERGY EXPENDITURE; EXTENSOR DIGITORUM LONGUS MUSCLE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; INSULIN RESISTANCE; LIPID DIET; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ORAL GLUCOSE TOLERANCE TEST; PROTEIN EXPRESSION; SKELETAL MUSCLE; SOLEUS MUSCLE; ADVERSE EFFECTS; ANIMAL; BODY COMPOSITION; C57BL MOUSE; ENERGY METABOLISM; GENETICS; GLUCOSE INTOLERANCE; HEART; MALE; METABOLISM; MUSCLE MITOCHONDRION; MYOCARDIAL REPERFUSION INJURY; OBESITY; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; RANDOMIZATION; TRANSGENIC MOUSE; UPREGULATION; WEIGHT GAIN;

ADIPOSITY; ANIMALS; BODY COMPOSITION; DIET, HIGH-FAT; ENERGY METABOLISM; GLUCOSE INTOLERANCE; HEART; INSULIN RESISTANCE; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; MYOCARDIAL REPERFUSION INJURY; OBESITY; OXYGEN CONSUMPTION; RANDOM ALLOCATION; SIRTUIN 1; UP-REGULATION; WEIGHT GAIN;

EID: 84908360911     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00001.2014     Document Type: Article

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