The TSC complex is required for the benefits of dietary protein restriction on stress resistance inVivo

Cell Reports

Volumn 8, Issue 4, 2014, Pages 1160-1170

  Harputlugil, Eylul ^a   Hine, Christopher ^a   Vargas, Dorathy ^a   Robertson, Lauren ^a   Manning, Brendan D ^a   Mitchell, James R ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ESSENTIAL AMINO ACID; GCN 2; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 2ALPHA; INSULIN; LACTATE DEHYDROGENASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; NONESSENTIAL AMINO ACID; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN S6; PROTEIN SERINE THREONINE KINASE; S6 KINASE; SOMATOMEDIN C; TRANSCRIPTION FACTOR FKHR; TUBERIN; UNCLASSIFIED DRUG; AMINO ACID; GENERAL CONTROL NONDEPRESSIBLE 2; INSULIN RECEPTOR; PEPTIDES AND PROTEINS; PHOSPHATIDYLINOSITOL 3 KINASE; TUBEROUS SCLEROSIS COMPLEX 1; EIF2AK4 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TUBEROUS SCLEROSIS COMPLEX 1 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID ANALYSIS; AMINO ACID BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; ENZYME PHOSPHORYLATION; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIVER ISCHEMIA; LIVER PROTECTION; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; STRESS; WEIGHT REDUCTION; ENZYME ACTIVATION; ENZYME INHIBITION; GENE DELETION; LIVER CELL; PROTEIN INTAKE; PROTEIN RESTRICTION; 129 MOUSE; ANIMAL; C57BL MOUSE; CELL CULTURE; DIET THERAPY; GENE INACTIVATION; INSULIN RESISTANCE; ISCHEMIA; LIVER; METABOLISM; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY; VASCULARIZATION;

MAMMALIA;

AMINO ACIDS, ESSENTIAL; ANIMALS; CELLS, CULTURED; DIET, PROTEIN-RESTRICTED; GENE KNOCKOUT TECHNIQUES; INSULIN RESISTANCE; ISCHEMIA; LIVER; MICE, 129 STRAIN; MICE, INBRED C57BL; MULTIPROTEIN COMPLEXES; PROTEIN-SERINE-THREONINE KINASES; REPERFUSION INJURY; STRESS, PHYSIOLOGICAL; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84908356915     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.07.018     Document Type: Article

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