메뉴 건너뛰기




Volumn 96, Issue 5, 2014, Pages 723-727

Wip: More than a wasp-interacting protein

Author keywords

Actin polymerization; Cytoskeleton; Immune cells; Immune synapse; Lymphocytes

Indexed keywords

CHAPERONE; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; PROTEIN KINASE C; UNCLASSIFIED DRUG; WASP INTERACTING PROTEIN; CARRIER PROTEIN; CYTOSKELETON PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN BINDING; SIGNAL PEPTIDE; WISKOTT ALDRICH SYNDROME PROTEIN;

EID: 84908270837     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2RU0314-162R     Document Type: Article
Times cited : (28)

References (128)
  • 1
    • 77949434124 scopus 로고    scopus 로고
    • New insights into the biology of Wiskott-Aldrich syndrome (WAS)
    • Thrasher, A. J. (2009) New insights into the biology of Wiskott-Aldrich syndrome (WAS). Hematol. Am. Soc. Hematol. Educ. Program 2009, 132-138.
    • (2009) Hematol. Am. Soc. Hematol. Educ. Program , vol.2009 , pp. 132-138
    • Thrasher, A.J.1
  • 3
    • 0029836850 scopus 로고    scopus 로고
    • Isolated X-linked thrombocytopenia in two unrelated families is associated with point mutations in the Wiskott-Aldrich syndrome protein gene
    • De Saint Basile, G., Lagelouse, R. D., Lambert, N., Schwarz, K., Le Mareck, B., Odent, S., Schlegel, N., Fischer, A. (1996) Isolated X-linked thrombocytopenia in two unrelated families is associated with point mutations in the Wiskott-Aldrich syndrome protein gene. J. Pediatr. 129, 56–62.
    • (1996) J. Pediatr , vol.129 , pp. 56-62
    • De Saint Basile, G.1    Lagelouse, R.D.2    Lambert, N.3    Schwarz, K.4    Le Mareck, B.5    Odent, S.6    Schlegel, N.7    Fischer, A.8
  • 4
    • 0027937223 scopus 로고
    • Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
    • following 922
    • Derry, J. M., Ochs, H. D., Francke, U. (1994) Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 79, following 922.
    • (1994) Cell 79
    • Derry, J.M.1    Ochs, H.D.2    Francke, U.3
  • 5
    • 67650581556 scopus 로고    scopus 로고
    • Recent advances in understanding the pathophysiology of Wiskott- Aldrich syndrome
    • Bosticardo, M., Marangoni, F., Aiuti, A., Villa, A., Grazia Roncarolo, M. (2009) Recent advances in understanding the pathophysiology of Wiskott- Aldrich syndrome. Blood 113, 6288–6295.
    • (2009) Blood , vol.113 , pp. 6288-6295
    • Bosticardo, M.1    Marangoni, F.2    Aiuti, A.3    Villa, A.4    Grazia Roncarolo, M.5
  • 6
    • 0033561727 scopus 로고    scopus 로고
    • Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein
    • Stewart, D. M., Tian, L., Nelson, D. L. (1999) Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein. J. Immunol. 162, 5019–5024.
    • (1999) J. Immunol , vol.162 , pp. 5019-5024
    • Stewart, D.M.1    Tian, L.2    Nelson, D.L.3
  • 7
    • 84864585880 scopus 로고    scopus 로고
    • Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics
    • Reicher, B., Joseph, N., David, A., Pauker, M. H., Perl, O., Barda-Saad, M. (2012) Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics. Mol. Cell. Biol. 32, 3153–3163.
    • (2012) Mol. Cell. Biol , vol.32 , pp. 3153-3163
    • Reicher, B.1    Joseph, N.2    David, A.3    Pauker, M.H.4    Perl, O.5    Barda-Saad, M.6
  • 8
    • 0031446340 scopus 로고    scopus 로고
    • WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells
    • Ramesh, N., Anton, I. M., Hartwig, J. H., Geha, R. S. (1997) WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc. Natl. Acad. Sci. USA 94, 14671–14676.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14671-14676
    • Ramesh, N.1    Anton, I.M.2    Hartwig, J.H.3    Geha, R.S.4
  • 11
    • 0036928182 scopus 로고    scopus 로고
    • Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation
    • Sasahara, Y., Rachid, R., Byrne, M. J., de la Fuente, M. A., Abraham, R. T., Ramesh, N., Geha, R. S. (2002) Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. Mol. Cell 10, 1269–1281.
    • (2002) Mol. Cell , vol.10 , pp. 1269-1281
    • Sasahara, Y.1    Rachid, R.2    Byrne, M.J.3    De La Fuente, M.A.4    Abraham, R.T.5    Ramesh, N.6    Geha, R.S.7
  • 14
    • 50649093112 scopus 로고    scopus 로고
    • WASP and WIP regulate podosomes in migrating leukocytes
    • Calle, Y., Anton, I. M., Thrasher, A. J., Jones, G. E. (2008) WASP and WIP regulate podosomes in migrating leukocytes. J. Microsc. 231, 494-505.
    • (2008) J. Microsc , vol.231 , pp. 494-505
    • Calle, Y.1    Anton, I.M.2    Thrasher, A.J.3    Jones, G.E.4
  • 15
    • 33847376308 scopus 로고    scopus 로고
    • Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages
    • Tsuboi, S. (2007) Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages. J. Immunol. 178, 2987–2995.
    • (2007) J. Immunol , vol.178 , pp. 2987-2995
    • Tsuboi, S.1
  • 16
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
    • Buccione, R., Orth, J. D., McNiven, M. A. (2004) Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat. Rev. Mol. Cell. Biol. 5, 647–657.
    • (2004) Nat. Rev. Mol. Cell. Biol , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 21
    • 33646013893 scopus 로고    scopus 로고
    • Profilin: Emerging concepts and lingering misconceptions. Trends Biochem
    • Yarmola, E. G., Bubb, M. R. (2006) Profilin: emerging concepts and lingering misconceptions. Trends Biochem. Sci. 31, 197–205.
    • (2006) Sci , vol.31 , pp. 197-205
    • Yarmola, E.G.1    Bubb, M.R.2
  • 22
    • 0034597092 scopus 로고    scopus 로고
    • Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex
    • Weed, S. A., Karginov, A. V., Schafer, D. A., Weaver, A. M., Kinley, A. W., Cooper, J. A., Parsons, J. T. (2000) Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex. J. Cell Biol. 151, 29–40.
    • (2000) J. Cell Biol , vol.151 , pp. 29-40
    • Weed, S.A.1    Karginov, A.V.2    Schafer, D.A.3    Weaver, A.M.4    Kinley, A.W.5    Cooper, J.A.6    Parsons, J.T.7
  • 23
    • 79151486181 scopus 로고    scopus 로고
    • The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells
    • Banon-Rodriguez, I., Monypenny, J., Ragazzini, C., Franco, A., Calle, Y., Jones, G. E., Anton, I. M. (2011) The cortactin-binding domain of WIP is essential for podosome formation and extracellular matrix degradation by murine dendritic cells. Eur. J. Cell. Biol. 90, 213–223.
    • (2011) Eur. J. Cell. Biol , vol.90 , pp. 213-223
    • Banon-Rodriguez, I.1    Monypenny, J.2    Ragazzini, C.3    Franco, A.4    Calle, Y.5    Jones, G.E.6    Anton, I.M.7
  • 24
    • 33645737558 scopus 로고    scopus 로고
    • Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling
    • Krzewski, K., Chen, X., Orange, J. S., Strominger, J. L. (2006) Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling. J. Cell Biol. 173, 121–132.
    • (2006) J. Cell Biol , vol.173 , pp. 121-132
    • Krzewski, K.1    Chen, X.2    Orange, J.S.3    Strominger, J.L.4
  • 25
    • 40649091406 scopus 로고    scopus 로고
    • WIP is essential for lytic granule polarization and NK cell cytotoxicity
    • Krzewski, K., Chen, X., Strominger, J. L. (2008) WIP is essential for lytic granule polarization and NK cell cytotoxicity. Proc. Natl. Acad. Sci. USA 105, 2568–2573.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 2568-2573
    • Krzewski, K.1    Chen, X.2    Strominger, J.L.3
  • 27
    • 0030026286 scopus 로고    scopus 로고
    • Modulation of a novel RNA in brain neurons by glucocorticoid and mineralocorticoid receptors
    • Masters, J. N., Cotman, S. L., Osterburg, H. H., Nichols, N. R., Finch, C. E. (1996) Modulation of a novel RNA in brain neurons by glucocorticoid and mineralocorticoid receptors. Neuroendocrinology 63, 28–38.
    • (1996) Neuroendocrinology , vol.63 , pp. 28-38
    • Masters, J.N.1    Cotman, S.L.2    Osterburg, H.H.3    Nichols, N.R.4    Finch, C.E.5
  • 28
    • 0030228574 scopus 로고    scopus 로고
    • CR16, a novel prolinerich protein expressed in rat brain neurons, binds to SH3 domains and is a MAP kinase substrate
    • Weiler, M. C., Smith, J. L., Masters, J. N. (1996) CR16, a novel prolinerich protein expressed in rat brain neurons, binds to SH3 domains and is a MAP kinase substrate. J. Mol. Neurosci. 7, 203–215.
    • (1996) J. Mol. Neurosci , vol.7 , pp. 203-215
    • Weiler, M.C.1    Smith, J.L.2    Masters, J.N.3
  • 29
    • 0035949469 scopus 로고    scopus 로고
    • CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family
    • Ho, H. Y., Rohatgi, R., Ma, L., Kirschner, M. W. (2001) CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc. Natl. Acad. Sci. USA 98, 11306–11311.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 11306-11311
    • Ho, H.Y.1    Rohatgi, R.2    Ma, L.3    Kirschner, M.W.4
  • 31
    • 3242660752 scopus 로고    scopus 로고
    • The mammalian verprolin homologue WIRE participates in receptor-mediated endocytosis and regulation of the actin filament system by distinct mechanisms
    • Aspenstrom, P. (2004) The mammalian verprolin homologue WIRE participates in receptor-mediated endocytosis and regulation of the actin filament system by distinct mechanisms. Exp. Cell. Res. 298, 485-498.
    • (2004) Exp. Cell. Res , vol.298 , pp. 485-498
    • Aspenstrom, P.1
  • 32
    • 0036083157 scopus 로고    scopus 로고
    • WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. Biochem. Biophys. Res
    • Kato, M., Miki, H., Kurita, S., Endo, T., Nakagawa, H., Miyamoto, S., Takenawa, T. (2002) WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. Biochem. Biophys. Res. Commun. 291, 41–47.
    • (2002) Commun , vol.291 , pp. 41-47
    • Kato, M.1    Miki, H.2    Kurita, S.3    Endo, T.4    Nakagawa, H.5    Miyamoto, S.6    Takenawa, T.7
  • 33
    • 13744252932 scopus 로고    scopus 로고
    • WICH, a member of WASP-interacting protein family, cross-links actin filaments
    • Kato, M., Takenawa, T. (2005) WICH, a member of WASP-interacting protein family, cross-links actin filaments. Biochem. Biophys. Res. Commun. 328, 1058–1066.
    • (2005) Biochem. Biophys. Res. Commun , vol.328 , pp. 1058-1066
    • Kato, M.1    Takenawa, T.2
  • 34
    • 77956879326 scopus 로고    scopus 로고
    • The mammalian verprolin, WIRE induces filopodia independent of N-WASP through IRSp 53
    • Misra, A., Rajmohan, R., Lim, R. P., Bhattacharyya, S., Thanabalu, T. (2010) The mammalian verprolin, WIRE induces filopodia independent of N-WASP through IRSp 53. Exp. Cell. Res. 316, 2810–2824.
    • (2010) Exp. Cell. Res , vol.316 , pp. 2810-2824
    • Misra, A.1    Rajmohan, R.2    Lim, R.P.3    Bhattacharyya, S.4    Thanabalu, T.5
  • 35
    • 0027488669 scopus 로고
    • A proline- rich protein, verprolin, involved in cytoskeletal organization and cellular growth in the yeast Saccharomyces cerevisiae
    • Donnelly, S. F., Pocklington, M. J., Pallotta, D., Orr, E. (1993) A proline- rich protein, verprolin, involved in cytoskeletal organization and cellular growth in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 10, 585–596.
    • (1993) Mol. Microbiol , vol.10 , pp. 585-596
    • Donnelly, S.F.1    Pocklington, M.J.2    Pallotta, D.3    Orr, E.4
  • 36
    • 34547755015 scopus 로고    scopus 로고
    • Verprolin function in endocytosis and actin organization. Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain
    • Thanabalu, T., Rajmohan, R., Meng, L., Ren, G., Vajjhala, P. R., Munn, A. L. (2007) Verprolin function in endocytosis and actin organization. Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain. FEBS J. 274, 4103–4125.
    • (2007) FEBS J , vol.274 , pp. 4103-4125
    • Thanabalu, T.1    Rajmohan, R.2    Meng, L.3    Ren, G.4    Vajjhala, P.R.5    Munn, A.L.6
  • 37
    • 25844469122 scopus 로고    scopus 로고
    • The verprolin family of proteins: Regulators of cell morphogenesis and endocytosis
    • Aspenström, P. (2005) The verprolin family of proteins: regulators of cell morphogenesis and endocytosis. FEBS Lett. 579, 5253–5259.
    • (2005) FEBS Lett , vol.579 , pp. 5253-5259
    • Aspenström, P.1
  • 39
    • 33644939588 scopus 로고    scopus 로고
    • WIP: A multifunctional protein involved in actin cytoskeleton regulation
    • Antón, I. M., Jones, G. E. (2006) WIP: a multifunctional protein involved in actin cytoskeleton regulation. Eur. J. Cell Biol. 85, 295–304.
    • (2006) Eur. J. Cell Biol , vol.85 , pp. 295-304
    • Antón, I.M.1    Jones, G.E.2
  • 40
    • 36048978084 scopus 로고    scopus 로고
    • WASP-interacting protein (WIP): Working in polymerisation and much more
    • Anton, I. M., Jones, G. E., Wandosell, F., Geha, R., Ramesh, N. (2007) WASP-interacting protein (WIP): working in polymerisation and much more. Trends Cell Biol. 17, 555–562.
    • (2007) Trends Cell Biol , vol.17 , pp. 555-562
    • Anton, I.M.1    Jones, G.E.2    Wandosell, F.3    Geha, R.4    Ramesh, N.5
  • 41
    • 70549106122 scopus 로고    scopus 로고
    • How depolymerization can promote polymerization: The case of actin and profilin
    • Yarmola, E. G., Bubb, M. R. (2009) How depolymerization can promote polymerization: the case of actin and profilin. Bioessays 31, 1150-1160.
    • (2009) Bioessays , vol.31 , pp. 1150-1160
    • Yarmola, E.G.1    Bubb, M.R.2
  • 42
    • 0032516877 scopus 로고    scopus 로고
    • The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck
    • Anton, I. M., Lu, W., Mayer, B. J., Ramesh, N., Geha, R. S. (1998) The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck. J. Biol. Chem. 273, 20992–20995.
    • (1998) J. Biol. Chem , vol.273 , pp. 20992-20995
    • Anton, I.M.1    Lu, W.2    Mayer, B.J.3    Ramesh, N.4    Geha, R.S.5
  • 43
    • 84878566800 scopus 로고    scopus 로고
    • WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization
    • Donnelly, S. K., Weisswange, I., Zettl, M., Way, M. (2013) WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization. Curr. Biol. 23, 999–1006.
    • (2013) Curr. Biol , vol.23 , pp. 999-1006
    • Donnelly, S.K.1    Weisswange, I.2    Zettl, M.3    Way, M.4
  • 44
    • 0037125912 scopus 로고    scopus 로고
    • The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs
    • Zettl, M., Way, M. (2002) The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs. Curr. Biol. 12, 1617–1622.
    • (2002) Curr. Biol , vol.12 , pp. 1617-1622
    • Zettl, M.1    Way, M.2
  • 45
    • 0037112347 scopus 로고    scopus 로고
    • Structure of the N-WASP EVH1 domain-WIP complex: Insight into the molecular basis of Wiskott-Aldrich Syndrome
    • Volkman, B. F., Prehoda, K. E., Scott, J. A., Peterson, F. C., Lim, W. A. (2002) Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome. Cell 111, 565-576.
    • (2002) Cell , vol.111 , pp. 565-576
    • Volkman, B.F.1    Prehoda, K.E.2    Scott, J.A.3    Peterson, F.C.4    Lim, W.A.5
  • 46
    • 34247179024 scopus 로고    scopus 로고
    • Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP
    • Peterson, F. C., Deng, Q., Zettl, M., Prehoda, K. E., Lim, W. A., Way, M., Volkman, B. F. (2007) Multiple WASP-interacting protein recognition motifs are required for a functional interaction with N-WASP. J. Biol. Chem. 282, 8446–8453.
    • (2007) J. Biol. Chem , vol.282 , pp. 8446-8453
    • Peterson, F.C.1    Deng, Q.2    Zettl, M.3    Prehoda, K.E.4    Lim, W.A.5    Way, M.6    Volkman, B.F.7
  • 47
    • 33846260879 scopus 로고    scopus 로고
    • A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain
    • Koduru, S., Massaad, M., Wilbur, C., Kumar, L., Geha, R., Ramesh, N. (2007) A novel anti-WIP monoclonal antibody detects an isoform of WIP that lacks the WASP binding domain. Biochem. Biophys. Res. Commun. 353, 875–881.
    • (2007) Biochem. Biophys. Res. Commun , vol.353 , pp. 875-881
    • Koduru, S.1    Massaad, M.2    Wilbur, C.3    Kumar, L.4    Geha, R.5    Ramesh, N.6
  • 48
    • 0029815611 scopus 로고    scopus 로고
    • N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
    • Miki, H., Miura, K., Takenawa, T. (1996) N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15, 5326–5335.
    • (1996) EMBO J , vol.15 , pp. 5326-5335
    • Miki, H.1    Miura, K.2    Takenawa, T.3
  • 52
    • 46149096223 scopus 로고    scopus 로고
    • WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport
    • Campellone, K. G., Webb, N. J., Znameroski, E. A., Welch, M. D. (2008) WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport. Cell 134, 148–161.
    • (2008) Cell , vol.134 , pp. 148-161
    • Campellone, K.G.1    Webb, N.J.2    Znameroski, E.A.3    Welch, M.D.4
  • 55
    • 0037105573 scopus 로고    scopus 로고
    • Normal Arp2/3 complex activation in platelets lacking WASp
    • Falet, H., Hoffmeister, K. M., Neujahr, R., Hartwig, J. H. (2002) Normal Arp2/3 complex activation in platelets lacking WASp. Blood 100, 2113–2122.
    • (2002) Blood , vol.100 , pp. 2113-2122
    • Falet, H.1    Hoffmeister, K.M.2    Neujahr, R.3    Hartwig, J.H.4
  • 56
    • 0034624753 scopus 로고    scopus 로고
    • Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
    • Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A., Rosen, M. K. (2000) Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404, 151–158.
    • (2000) Nature , vol.404 , pp. 151-158
    • Kim, A.S.1    Kakalis, L.T.2    Abdul-Manan, N.3    Liu, G.A.4    Rosen, M.K.5
  • 57
    • 77649153819 scopus 로고    scopus 로고
    • WASP: A key immunological multitasker. Nat
    • Thrasher, A. J., Burns, S. O. (2010) WASP: a key immunological multitasker. Nat. Rev. Immunol. 10, 182–192.
    • (2010) Rev. Immunol , vol.10 , pp. 182-192
    • Thrasher, A.J.1    Burns, S.O.2
  • 58
    • 3242671847 scopus 로고    scopus 로고
    • Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex
    • Ho, H. Y., Rohatgi, R., Lebensohn, A. M., Le, M., Li, J., Gygi, S. P., Kirschner, M. W. (2004) Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Cell 118, 203–216.
    • (2004) Cell , vol.118 , pp. 203-216
    • Ho, H.Y.1    Rohatgi, R.2    Lebensohn, A.M.3    Le, M.4    Li, J.5    Gygi, S.P.6    Kirschner, M.W.7
  • 59
    • 84872056958 scopus 로고    scopus 로고
    • Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration
    • Worth, A. J., Metelo, J., Bouma, G., Moulding, D., Fritzsche, M., Vernay, B., Charras, G., Cory, G. O., Thrasher, A. J., Burns, S. O. (2012) Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration. Blood 121, 72–84.
    • (2012) Blood , vol.121 , pp. 72-84
    • Worth, A.J.1    Metelo, J.2    Bouma, G.3    Moulding, D.4    Fritzsche, M.5    Vernay, B.6    Charras, G.7    Cory, G.O.8    Thrasher, A.J.9    Burns, S.O.10
  • 60
    • 84867395262 scopus 로고    scopus 로고
    • WIP: WASP-interacting proteins at invadopodia and podosomes
    • García, E., Jones, G. E., Machesky, L. M., Antón, I. M. (2012) WIP: WASP-interacting proteins at invadopodia and podosomes. Eur. J. Cell Biol. 91, 869–877.
    • (2012) Eur. J. Cell Biol , vol.91 , pp. 869-877
    • García, E.1    Jones, G.E.2    Machesky, L.M.3    Antón, I.M.4
  • 61
    • 35648960360 scopus 로고    scopus 로고
    • Structurefunction analysis of the WIP role in T cell receptor-stimulated NFAT activation: Evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory
    • Dong, X., Patino-Lopez, G., Candotti, F., Shaw, S. (2007) Structurefunction analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory. J. Biol. Chem. 282, 30303-30310.
    • (2007) J. Biol. Chem , vol.282 , pp. 30303-30310
    • Dong, X.1    Patino-Lopez, G.2    Candotti, F.3    Shaw, S.4
  • 62
    • 84860246467 scopus 로고    scopus 로고
    • Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET
    • Pauker, M. H., Hassan, N., Noy, E., Reicher, B., Barda-Saad, M. (2012) Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET. Sci. Signal 5, rs3.
    • (2012) Sci. Signal , vol.5 , pp. 3
    • Pauker, M.H.1    Hassan, N.2    Noy, E.3    Reicher, B.4    Barda-Saad, M.5
  • 63
    • 79953654170 scopus 로고    scopus 로고
    • A peptide derived from the Wiskott- Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding
    • Massaad, M. J., Ramesh, N., Le Bras, S., Giliani, S., Notarangelo, L. D., Al-Herz, W., Geha, R. S. (2011) A peptide derived from the Wiskott- Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding. J. Allergy Clin. Immunol. 127, 998–1005.e2.
    • (2011) J. Allergy Clin. Immunol , vol.127 , pp. 998-1005
    • Massaad, M.J.1    Ramesh, N.2    Le Bras, S.3    Giliani, S.4    Notarangelo, L.D.5    Al-Herz, W.6    Geha, R.S.7
  • 64
    • 0036850180 scopus 로고    scopus 로고
    • Sustained activation of N-WASP through phosphorylation is essential for neurite extension
    • Suetsugu, S., Hattori, M., Miki, H., Tezuka, T., Yamamoto, T., Mikoshiba, K., Takenawa, T. (2002) Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev. Cell. 3, 645–658.
    • (2002) Dev. Cell , vol.3 , pp. 645-658
    • Suetsugu, S.1    Hattori, M.2    Miki, H.3    Tezuka, T.4    Yamamoto, T.5    Mikoshiba, K.6    Takenawa, T.7
  • 65
    • 33646863080 scopus 로고    scopus 로고
    • A complex of Wiskott-Aldrich syndrome protein with mammalian verprolins plays an important role in monocyte chemotaxis
    • Tsuboi, S. (2006) A complex of Wiskott-Aldrich syndrome protein with mammalian verprolins plays an important role in monocyte chemotaxis. J. Immunol. 176, 6576–6585.
    • (2006) J. Immunol , vol.176 , pp. 6576-6585
    • Tsuboi, S.1
  • 66
    • 79955892237 scopus 로고    scopus 로고
    • Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo
    • Jin, P., Duan, R., Luo, F., Zhang, G., Hong, S. N., Chen, E. H. (2011) Competition between Blown fuse and WASP for WIP binding regulates the dynamics of WASP-dependent actin polymerization in vivo. Dev. Cell 20, 623–638.
    • (2011) Dev. Cell , vol.20 , pp. 623-638
    • Jin, P.1    Duan, R.2    Luo, F.3    Zhang, G.4    Hong, S.N.5    Chen, E.H.6
  • 67
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C. R., Freiberg, B. A., Kupfer, H., Sciaky, N., Kupfer, A. (1998) Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82–86.
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 70
    • 0027418818 scopus 로고
    • Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells
    • Baier, G., Telford, D., Giampa, L., Coggeshall, K. M., Baier-Bitterlich, G., Isakov, N., Altman, A. (1993) Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells. J. Biol. Chem. 268, 4997–5004.
    • (1993) J. Biol. Chem , vol.268 , pp. 4997-5004
    • Baier, G.1    Telford, D.2    Giampa, L.3    Coggeshall, K.M.4    Baier-Bitterlich, G.5    Isakov, N.6    Altman, A.7
  • 72
    • 3242790172 scopus 로고    scopus 로고
    • Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses
    • Marsland, B. J., Soos, T. J., Spath, G., Littman, D. R., Kopf, M. (2004) Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses. J. Exp. Med. 200, 181-189.
    • (2004) J. Exp. Med , vol.200 , pp. 181-189
    • Marsland, B.J.1    Soos, T.J.2    Spath, G.3    Littman, D.R.4    Kopf, M.5
  • 73
    • 0036952044 scopus 로고    scopus 로고
    • Protein kinase C-theta (PKC theta): A key enzyme in T cell life and death
    • Altman, A., Villalba, M. (2002) Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death. J. Biochem. 132, 841–846.
    • (2002) J. Biochem , vol.132 , pp. 841-846
    • Altman, A.1    Villalba, M.2
  • 74
    • 0036285316 scopus 로고    scopus 로고
    • Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias
    • Villalba, M., Altman, A. (2002) Protein kinase C-theta (PKCtheta), a potential drug target for therapeutic intervention with human T cell leukemias. Curr. Cancer Drug Targets 2, 125–137.
    • (2002) Curr. Cancer Drug Targets , vol.2 , pp. 125-137
    • Villalba, M.1    Altman, A.2
  • 75
    • 0031012266 scopus 로고    scopus 로고
    • Selective modulation of protein kinase C-theta during T-cell activation
    • Monks, C. R., Kupfer, H., Tamir, I., Barlow, A., Kupfer, A. (1997) Selective modulation of protein kinase C-theta during T-cell activation. Nature 385, 83–86.
    • (1997) Nature , vol.385 , pp. 83-86
    • Monks, C.R.1    Kupfer, H.2    Tamir, I.3    Barlow, A.4    Kupfer, A.5
  • 76
    • 79960894775 scopus 로고    scopus 로고
    • PKC-_ function at the immunological synapse: Prospects for therapeutic targeting
    • Zanin-Zhorov, A., Dustin, M. L., Blazar, B. R. (2011) PKC-_ function at the immunological synapse: prospects for therapeutic targeting. Trends Immunol. 32, 358–363.
    • (2011) Trends Immunol , vol.32 , pp. 358-363
    • Zanin-Zhorov, A.1    Dustin, M.L.2    Blazar, B.R.3
  • 77
    • 79959376445 scopus 로고    scopus 로고
    • A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells
    • Quann, E. J., Liu, X., Altan-Bonnet, G., Huse, M. (2011) A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells. Nat. Immunol. 12, 647–654.
    • (2011) Nat. Immunol , vol.12 , pp. 647-654
    • Quann, E.J.1    Liu, X.2    Altan-Bonnet, G.3    Huse, M.4
  • 79
    • 0028961573 scopus 로고
    • Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
    • Valitutti, S., Dessing, M., Aktories, K., Gallati, H., Lanzavecchia, A. (1995) Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J. Exp. Med. 181, 577–584.
    • (1995) J. Exp. Med , vol.181 , pp. 577-584
    • Valitutti, S.1    Dessing, M.2    Aktories, K.3    Gallati, H.4    Lanzavecchia, A.5
  • 80
    • 34748878938 scopus 로고    scopus 로고
    • Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility
    • Yam, P. T., Wilson, C. A., Ji, L., Hebert, B., Barnhart, E. L., Dye, N. A., Wiseman, P. W., Danuser, G., Theriot, J. A. (2007) Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility. J. Cell Biol. 178, 1207–1221.
    • (2007) J. Cell Biol , vol.178 , pp. 1207-1221
    • Yam, P.T.1    Wilson, C.A.2    Ji, L.3    Hebert, B.4    Barnhart, E.L.5    Dye, N.A.6    Wiseman, P.W.7    Danuser, G.8    Theriot, J.A.9
  • 81
    • 84874207192 scopus 로고    scopus 로고
    • T lymphocyte myosin IIA is required for maturation of the immunological synapse. Front
    • Kumari, S., Vardhana, S., Cammer, M., Curado, S., Santos, L., Sheetz, M. P., Dustin, M. L. (2012) T lymphocyte myosin IIA is required for maturation of the immunological synapse. Front. Immunol. 3, 230.
    • (2012) Immunol , vol.3 , pp. 230
    • Kumari, S.1    Vardhana, S.2    Cammer, M.3    Curado, S.4    Santos, L.5    Sheetz, M.P.6    Dustin, M.L.7
  • 82
    • 0037008772 scopus 로고    scopus 로고
    • Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO 1
    • Scott, M. P., Zappacosta, F., Kim, E. Y., Annan, R. S., Miller, W. T. (2002) Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO 1. J. Biol. Chem. 277, 28238–28246.
    • (2002) J. Biol. Chem , vol.277 , pp. 28238-28246
    • Scott, M.P.1    Zappacosta, F.2    Kim, E.Y.3    Annan, R.S.4    Miller, W.T.5
  • 83
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys
    • Yamaguchi, H., Condeelis, J. (2007) Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys. Acta 1773, 642–652.
    • (2007) Acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 84
    • 33745626457 scopus 로고    scopus 로고
    • Cortactin has an essential and specific role in osteoclast actin assembly. Mol. Biol
    • Tehrani, S., Faccio, R., Chandrasekar, I., Ross, F. P., Cooper, J. A. (2006) Cortactin has an essential and specific role in osteoclast actin assembly. Mol. Biol. Cell 17, 2882–2895.
    • (2006) Cell , vol.17 , pp. 2882-2895
    • Tehrani, S.1    Faccio, R.2    Chandrasekar, I.3    Ross, F.P.4    Cooper, J.A.5
  • 85
    • 44149106941 scopus 로고    scopus 로고
    • A new role for cortactin in invadopodia: Regulation of protease secretion
    • Clark, E. S., Weaver, A. M. (2008) A new role for cortactin in invadopodia: regulation of protease secretion. Eur. J. Cell Biol. 87, 581–590.
    • (2008) Eur. J. Cell Biol , vol.87 , pp. 581-590
    • Clark, E.S.1    Weaver, A.M.2
  • 86
    • 0034654348 scopus 로고    scopus 로고
    • Cutting edge: WIP, a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation
    • Savoy, D. N., Billadeau, D. D., Leibson, P. J. (2000) Cutting edge: WIP, a binding partner for Wiskott-Aldrich syndrome protein, cooperates with Vav in the regulation of T cell activation. J. Immunol. 164, 2866-2870.
    • (2000) J. Immunol , vol.164 , pp. 2866-2870
    • Savoy, D.N.1    Billadeau, D.D.2    Leibson, P.J.3
  • 87
    • 0033578374 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages
    • Linder, S., Nelson, D., Weiss, M., Aepfelbacher, M. (1999) Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages. Proc. Natl. Acad. Sci. USA 96, 9648–9653.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9648-9653
    • Linder, S.1    Nelson, D.2    Weiss, M.3    Aepfelbacher, M.4
  • 88
    • 3142585003 scopus 로고    scopus 로고
    • Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: Ability of IL-2 to correct NK cell functional defect
    • Gismondi, A., Cifaldi, L., Mazza, C., Giliani, S., Parolini, S., Morrone, S., Jacobelli, J., Bandiera, E., Notarangelo, L., Santoni, A. (2004) Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect. Blood 104, 436–443.
    • (2004) Blood , vol.104 , pp. 436-443
    • Gismondi, A.1    Cifaldi, L.2    Mazza, C.3    Giliani, S.4    Parolini, S.5    Morrone, S.6    Jacobelli, J.7    Bandiera, E.8    Notarangelo, L.9    Santoni, A.10
  • 89
    • 12344272845 scopus 로고    scopus 로고
    • Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton
    • Barda-Saad, M., Braiman, A., Titerence, R., Bunnell, S. C., Barr, V. A., Samelson, L. E. (2005) Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. Nat. Immunol. 6, 80–89.
    • (2005) Nat. Immunol , vol.6 , pp. 80-89
    • Barda-Saad, M.1    Braiman, A.2    Titerence, R.3    Bunnell, S.C.4    Barr, V.A.5    Samelson, L.E.6
  • 91
    • 79959396065 scopus 로고    scopus 로고
    • Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization
    • Pauker, M. H., Reicher, B., Fried, S., Perl, O., Barda-Saad, M. (2011) Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization. Mol. Cell. Biol. 31, 2653–2666.
    • (2011) Mol. Cell. Biol , vol.31 , pp. 2653-2666
    • Pauker, M.H.1    Reicher, B.2    Fried, S.3    Perl, O.4    Barda-Saad, M.5
  • 92
    • 0029126878 scopus 로고
    • Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains
    • Rivero-Lezcano, O. M., Marcilla, A., Sameshima, J. H., Robbins, K. C. (1995) Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains. Mol. Cell. Biol. 15, 5725–5731.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 5725-5731
    • Rivero-Lezcano, O.M.1    Marcilla, A.2    Sameshima, J.H.3    Robbins, K.C.4
  • 96
    • 22744434624 scopus 로고    scopus 로고
    • Cortactin promotes cell motility by enhancing lamellipodial persistence
    • Bryce, N. S., Clark, E. S., Leysath, J. L., Currie, J. D., Webb, D. J., Weaver, A. M. (2005) Cortactin promotes cell motility by enhancing lamellipodial persistence. Curr. Biol. 15, 1276–1285.
    • (2005) Curr. Biol , vol.15 , pp. 1276-1285
    • Bryce, N.S.1    Clark, E.S.2    Leysath, J.L.3    Currie, J.D.4    Webb, D.J.5    Weaver, A.M.6
  • 97
    • 33644882476 scopus 로고    scopus 로고
    • Cortactin regulates podosome formation: Roles of the protein interaction domains
    • Webb, B. A., Eves, R., Mak, A. S. (2006) Cortactin regulates podosome formation: roles of the protein interaction domains. Exp. Cell. Res. 312, 760–769.
    • (2006) Exp. Cell. Res , vol.312 , pp. 760-769
    • Webb, B.A.1    Eves, R.2    Mak, A.S.3
  • 99
    • 80054710649 scopus 로고    scopus 로고
    • Hck is a key regulator of gene expression in alternatively activated human monocytes
    • Bhattacharjee, A., Pal, S., Feldman, G. M., Cathcart, M. K. (2011) Hck is a key regulator of gene expression in alternatively activated human monocytes. J. Biol. Chem. 286, 36709–36723.
    • (2011) J. Biol. Chem , vol.286 , pp. 36709-36723
    • Bhattacharjee, A.1    Pal, S.2    Feldman, G.M.3    Cathcart, M.K.4
  • 100
    • 79960734724 scopus 로고    scopus 로고
    • Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells
    • Sato, M., Sawahata, R., Takenouchi, T., Kitani, H. (2011) Identification of Fyn as the binding partner for the WASP N-terminal domain in T cells. Int. Immunol. 23, 493–502.
    • (2011) Int. Immunol , vol.23 , pp. 493-502
    • Sato, M.1    Sawahata, R.2    Takenouchi, T.3    Kitani, H.4
  • 102
    • 80155136196 scopus 로고    scopus 로고
    • Studies of novel interactions between Nck and VAV SH3 domains
    • Pauker, M. H., Barda-Saad, M. (2011) Studies of novel interactions between Nck and VAV SH3 domains. Commun. Integr. Biol. 4, 175–177.
    • (2011) Commun. Integr. Biol , vol.4 , pp. 175-177
    • Pauker, M.H.1    Barda-Saad, M.2
  • 104
    • 0028999988 scopus 로고
    • A functional T-cell receptor signaling pathway is required for p95vav activity
    • Wu, J., Katzav, S., Weiss, A. (1995) A functional T-cell receptor signaling pathway is required for p95vav activity. Mol. Cell. Biol. 15, 4337-4346.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 4337-4346
    • Wu, J.1    Katzav, S.2    Weiss, A.3
  • 108
    • 0030816363 scopus 로고    scopus 로고
    • Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation
    • Gallego, M. D., Santamaria, M., Pena, J., Molina, I. J. (1997) Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulation. Blood 90, 3089–3097.
    • (1997) Blood , vol.90 , pp. 3089-3097
    • Gallego, M.D.1    Santamaria, M.2    Pena, J.3    Molina, I.J.4
  • 109
    • 33846260575 scopus 로고    scopus 로고
    • WIP null mice display a progressive immunological disorder that resembles Wiskott-Aldrich syndrome
    • Curcio, C., Pannellini, T., Lanzardo, S., Forni, G., Musiani, P., Anton, I. M. (2007) WIP null mice display a progressive immunological disorder that resembles Wiskott-Aldrich syndrome. J. Pathol. 211, 67–75.
    • (2007) J. Pathol , vol.211 , pp. 67-75
    • Curcio, C.1    Pannellini, T.2    Lanzardo, S.3    Forni, G.4    Musiani, P.5    Anton, I.M.6
  • 111
    • 0027444915 scopus 로고
    • T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses
    • Molina, I. J., Sancho, J., Terhorst, C., Rosen, F. S., Remold-O’Donnell, E. (1993) T cells of patients with the Wiskott-Aldrich syndrome have a restricted defect in proliferative responses. J. Immunol. 151, 4383–4390.
    • (1993) J. Immunol , vol.151 , pp. 4383-4390
    • Molina, I.J.1    Sancho, J.2    Terhorst, C.3    Rosen, F.S.4    Remold-O’donnell, E.5
  • 113
    • 77951020111 scopus 로고    scopus 로고
    • Impaired NK-cell migration in WAS/XLT patients: Role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state
    • Stabile, H., Carlino, C., Mazza, C., Giliani, S., Morrone, S., Notarangelo, L. D., Notarangelo, L. D., Santoni, A., Gismondi, A. (2010) Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state. Blood 115, 2818–2826.
    • (2010) Blood , vol.115 , pp. 2818-2826
    • Stabile, H.1    Carlino, C.2    Mazza, C.3    Giliani, S.4    Morrone, S.5    Notarangelo, L.D.6    Notarangelo, L.D.7    Santoni, A.8    Gismondi, A.9
  • 115
    • 73949146436 scopus 로고    scopus 로고
    • Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP
    • Falet, H., Marchetti, M. P., Hoffmeister, K. M., Massaad, M. J., Geha, R. S., Hartwig, J. H. (2009) Platelet-associated IgAs and impaired GPVI responses in platelets lacking WIP. Blood 114, 4729–4737.
    • (2009) Blood , vol.114 , pp. 4729-4737
    • Falet, H.1    Marchetti, M.P.2    Hoffmeister, K.M.3    Massaad, M.J.4    Geha, R.S.5    Hartwig, J.H.6
  • 116
    • 0028116532 scopus 로고
    • A multiinstitutional survey of the Wiskott-Aldrich syndrome
    • Sullivan, K. E., Mullen, C. A., Blaese, R. M., Winkelstein, J. A. (1994) A multiinstitutional survey of the Wiskott-Aldrich syndrome. J. Pediatr. 125, 876–885.
    • (1994) J. Pediatr , vol.125 , pp. 876-885
    • Sullivan, K.E.1    Mullen, C.A.2    Blaese, R.M.3    Winkelstein, J.A.4
  • 118
    • 0018834588 scopus 로고
    • The Wiskott-Aldrich syndrome: Studies of lymphocytes, granulocytes, and platelets
    • Ochs, H. D., Slichter, S. J., Harker, L. A., Von Behrens, W. E., Clark, R. A., Wedgwood, R. J. (1980) The Wiskott-Aldrich syndrome: studies of lymphocytes, granulocytes, and platelets. Blood 55, 243–252.
    • (1980) Blood , vol.55 , pp. 243-252
    • Ochs, H.D.1    Slichter, S.J.2    Harker, L.A.3    Von Behrens, W.E.4    Clark, R.A.5    Wedgwood, R.J.6
  • 119
    • 0030824870 scopus 로고    scopus 로고
    • Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure
    • Semple, J. W., Siminovitch, K. A., Mody, M., Milev, Y., Lazarus, A. H., Wright, J. F., Freedman, J. (1997) Flow cytometric analysis of platelets from children with the Wiskott-Aldrich syndrome reveals defects in platelet development, activation and structure. Br. J. Haematol. 97, 747–754.
    • (1997) Br. J. Haematol , vol.97 , pp. 747-754
    • Semple, J.W.1    Siminovitch, K.A.2    Mody, M.3    Milev, Y.4    Lazarus, A.H.5    Wright, J.F.6    Freedman, J.7
  • 120
    • 61449190767 scopus 로고    scopus 로고
    • WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function
    • Westerberg, L. S., de la Fuente, M. A., Wermeling, F., Ochs, H. D., Karlsson, M. C., Snapper, S. B., Notarangelo, L. D. (2008) WASP confers selective advantage for specific hematopoietic cell populations and serves a unique role in marginal zone B-cell homeostasis and function. Blood 112, 4139–4147.
    • (2008) Blood , vol.112 , pp. 4139-4147
    • Westerberg, L.S.1    De La Fuente, M.A.2    Wermeling, F.3    Ochs, H.D.4    Karlsson, M.C.5    Snapper, S.B.6    Notarangelo, L.D.7
  • 121
    • 80053626114 scopus 로고    scopus 로고
    • The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling
    • Calvez, R., Lafouresse, F., De Meester, J., Galy, A., Valitutti, S., Dupre, L. (2011) The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling. Haematologica 96, 1415–1423.
    • (2011) Haematologica , vol.96 , pp. 1415-1423
    • Calvez, R.1    Lafouresse, F.2    De Meester, J.3    Galy, A.4    Valitutti, S.5    Dupre, L.6
  • 122
    • 3242762840 scopus 로고    scopus 로고
    • Differential roles for Wiskott- Aldrich syndrome protein in immune synapse formation and IL-2 production
    • Cannon, J. L., Burkhardt, J. K. (2004) Differential roles for Wiskott- Aldrich syndrome protein in immune synapse formation and IL-2 production. J. Immunol. 173, 1658–1662.
    • (2004) J. Immunol , vol.173 , pp. 1658-1662
    • Cannon, J.L.1    Burkhardt, J.K.2
  • 123
    • 68449092963 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome: Immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation
    • Bouma, G., Burns, S. O., Thrasher, A. J. (2009) Wiskott-Aldrich syndrome: immunodeficiency resulting from defective cell migration and impaired immunostimulatory activation. Immunobiology 214, 778–790.
    • (2009) Immunobiology , vol.214 , pp. 778-790
    • Bouma, G.1    Burns, S.O.2    Thrasher, A.J.3
  • 124
    • 0026469733 scopus 로고
    • Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome
    • Simon, H. U., Mills, G. B., Hashimoto, S., Siminovitch, K. A. (1992) Evidence for defective transmembrane signaling in B cells from patients with Wiskott-Aldrich syndrome. J. Clin. Invest. 90, 1396–1405.
    • (1992) J. Clin. Invest , vol.90 , pp. 1396-1405
    • Simon, H.U.1    Mills, G.B.2    Hashimoto, S.3    Siminovitch, K.A.4
  • 128
    • 33745482350 scopus 로고    scopus 로고
    • Inhibition of calpain stabilises podosomes and impairs dendritic cell motility
    • Calle, Y., Carragher, N. O., Thrasher, A. J., Jones, G. E. (2006) Inhibition of calpain stabilises podosomes and impairs dendritic cell motility. J. Cell Sci. 119, 2375–2385.
    • (2006) J. Cell Sci , vol.119 , pp. 2375-2385
    • Calle, Y.1    Carragher, N.O.2    Thrasher, A.J.3    Jones, G.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.