A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding

Journal of Allergy and Clinical Immunology

Volumn 127, Issue 4, 2011, Pages

  Massaad, Michel J ^a,b   Ramesh, Narayanaswamy ^a,b   Le Bras, Severine ^a,b   Giliani, Silvia ^c   Notarangelo, Lucia D ^d   Al Herz, Waleed ^e   Notarangelo, Luigi D ^a,b   Geha, Raif S ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF BRESCIA   (Italy)

^d SPEDALI CIVILI   (Italy)

^e AL SABAH HOSPITAL   (Kuwait)

Author keywords

actin cytoskeleton; T cells; WASP; WIP; Wiskott Aldrich syndrome

Indexed keywords

ACTIN; AMINO ACID; CD3 ANTIBODY; GREEN FLUORESCENT PROTEIN; UNCLASSIFIED DRUG; WISKOTT ALDRICH SYNDROME PROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN INTERACTING PROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL FUNCTION; CELL SELECTION; CONTROLLED STUDY; ELECTROPORATION; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LYMPHOCYTE; MISSENSE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PSEUDOPODIUM; T LYMPHOCYTE; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; WISKOTT ALDRICH SYNDROME;

EID: 79953654170     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.01.015     Document Type: Article

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