The mammalian verprolin homologue WIRE participates in receptor-mediated endocytosis and regulation of the actin filament system by distinct mechanisms

Experimental Cell Research

Volumn 298, Issue 2, 2004, Pages 485-498

  Aspenström, Pontus ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

Author keywords

Actin; Endocytosis; Filopodia; PDGF; WASP; WIP

Indexed keywords

FUNGAL PROTEIN; GENE PRODUCT; PLATELET DERIVED GROWTH FACTOR B; PROTEIN CR 16; PROTEIN WIP; PROTEIN WIRE; UNCLASSIFIED DRUG; VERPROLIN; WISKOTT ALDRICH SYNDROME PROTEIN;

ACTIN FILAMENT; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY;

MAMMALIA;

EID: 3242660752     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.04.050     Document Type: Article

References (40)

1. Thrasher A.J. WASp in immune-system organization and function. Nat. Rev. Immunol. 2:2002;635-646
2. Ochs H.D. The Wiskott-Aldrich syndrome. Springer Semin. Immunopathol. 19:1998;435-458
3. Derry J.M.J., Ochs H.D., Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell. 78:1994;635-644. [published Erratum Cell 79, following 922]
4. Molina I.J., Kenney D.M., Rosen F.S., Remold-O'Donnell E. T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome. J. Exp. Med. 176:1992;867-874
5. Badour K., Zhang J., Siminovitch K.A. The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation. Immunol. Rev. 192:2003;98-112
6. Pollard T.D., Blanchoin L., Mullins R.D. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu. Rev. Biophys. Biomol. Struct. 29:2000;545-576
7. Miki H., Miura K., Takenawa T. N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15:1996;5326-5335
8. Sossey-Alaoui K., Head K., Nowak N., Cowell J.K. Genomic organization and expression profile of the human and mouse WAVE gene family. Mamm. Genome. 14:2003;314-322
9. Miki H., Suetsugu S., Takenawa T. WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 17:1998;6932-6941
10. Suetsugu S., Miki H., Takenawa T. Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex. Biochem. Biophys. Res. Commun. 260:1999;296-302
11. Rohatgi R., Ma L., Miki H., Lopez M., Kirchhausen T., Takenawa T., Kirschner M.W. The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell. 97:1999;221-231
12. Machesky L., Insall R.H. Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex. Curr. Biol. 8:1998;1347-1356
13. Burbelo P., Drechsel D., Hall A. A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J. Biol. Chem. 270:1995;29071-29074
14. Symons M., Derry J.M.J., Karlak B., Jiang S., Lemahieu V., McCormick F., Francke U., Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell. 84:1996;723-734
15. Aspenström P., Fransson Å., Saras J. The Rho GTPases have diverse effects on the organisation of the actin filament system. Biochem. J. 377:2004;327-337
16. Ramesh N., Antón I.M., Hartwig J.H., Geha R.S. WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells. Proc. Natl. Acad. Sci. U. S. A. 94:1997;14676-15671
17. Stewart D.M., Tian L., Nelson D.L. Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein. J. Immunol. 162:1999;5019-5024
18. Kim A.S., Kakalis L.T., Abdul-Manan N., Liu G.A., Rosen M.K. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature. 404:2000;151-158
19. Torres E., Rosen M.K. Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. Mol. Cell. 11:2003;1215-1227
20. Cory G.O.C., Cramer R., Blanchoin L., Ridley A.J. Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP. Mol. Cell. 11:2003;1229-1239
21. Vaduva E., Martin N.C., Hopper A.K. Actin-binding verprolin is a polarity development protein required for the morphogenesis and function of the yeast actin cytoskeleton. J. Cell Biol. 139:1997;1821-1833
22. Aspenström P. The WASP-binding protein WIRE has a role in the regulation of the actin filament system downstream of the platelet-derived growth factor receptor. Exp. Cell Res. 279:2002;21-33
23. Kato M., Miki H., Kurita S., Endo T., Nakagawa H., Miyamoto S., Takenawa T. WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation. Biochem. Biophys. Res. Commun. 291:2002;41-47
24. Ho H.-Y.H., Rohatgi R., Ma L., Kirschner M.W. CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family. Proc. Natl. Acad. Sci. U. S. A. 98:2001;11306-11311
25. Naqvi S.N., Zahn R., Mitchell D.A., Stevenson B.J., Munn A.L. The WASp homologue Las17p functions with the WIP homologue End5p/verprolin and is essential for endocytosis in yeast. Curr. Biol. 8:1998;959-962
26. Martinez-Quiles N., Rohatgi R., Antón I.M., Medina M., Saville S.P., Miki H., Yamaguchi H., Takenawa T., Hartwig J.H., Geha R.S., Ramesh N. WIP regulates N-WASP-mediated actin polymerization and filopodium formation. Nat. Cell Biol. 3:2001;484-491
27. Moreau V., Frischknecht F., Reckmann I., Vincentelli R., Rabut G., Stewart D. M A Way, complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization. Nat. Cell Biol. 2:2000;441-448
28. Vetterkind S., Miki H., Takenawa T., Klawitz I., Scheidtmann K.-H., Preuss U. The rat homologue of Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) associates with actin filaments, recruits N-WASP from the nucleus, and mediates mobilization of actin from stress fibers in favor of filopodia formation. J. Biol. Chem. 277:2001;87-95
29. Antón I.M., Saville S.P., Byrne M.J., Curcio C., Ramesh N., Hartwig J.H., Geha R.S. WIP participates in actin reorganization and ruffle formation induced by PDGF. J. Cell Sci. 116:2003;2443-2451
30. Eriksson A., Siegbahn A., Westermark B., Heldin C.-H., Claesson-Welsh L. PDGF alpha- and beta-receptors activate unique and common signal transduction pathways. EMBO J. 11:1992;543-550
31. Renfranz P.J., Beckerle M.C. Doing (F/L)PPPPs: EVH1 domains and their proline-rich partners in cell polarity and migration. Curr. Opin. Cell Biol. 14:2002;88-103
32. Volkman B.F., Prehoda K.E., Scott J.A., Peterson F.C., Lim W.A. Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich syndrome. Cell. 111:2002;565-576
33. Rong S.-B., Vihinen M. Structural basis of Wiskott-Aldrich syndrome causing mutations in the WH1 domain. J. Mol. Med. 78:2000;530-537
34. Prehoda K.E., Lee D.J., Lim W.A. Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly. Cell. 97:1999;471-480
35. Zettl M., Way M. The WH1 and EVH1 domains of WASP and Ena/VASP family members bind distinct sequence motifs. Curr. Biol. 12:2002;1617-1622
36. Kinley A.W., Weed S.A., Weaver A.M., Kargianov A.V., Bissonette E., Cooper J.A., Parsons J.T. Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion. Curr. Biol. 13:2003;384-393
37. Chang F.S., Stefan C.J., Blumer K.J.A. WASp homolog powers actin polymerization-dependent motility of endosomes in vivo. Curr. Biol. 13:2003;455-463
38. Taunton J., Rowning B.A., Coughlin M.L., Wu M., Moon R.T., Mitchison T.J., Larabell C.A. Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. J. Cell Biol. 148:2000;519-530
39. Kessels M.M., Qualmann B. Syndapins integrate N-WASP in receptor-mediated endocytosis. EMBO J. 21:2002;6083-6094
40. Otsuki M., Itoh T., Takenawa T. Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin a in response to epidermal growth factor. J. Biol. Chem. 278:2003;6461-6469