Functional cooperation between the proteins Nck and ADAP is fundamental for actin reorganization

Molecular and Cellular Biology

Volumn 31, Issue 13, 2011, Pages 2653-2666

  Pauker, Maor H ^a   Reicher, Barak ^a   Fried, Sophie ^a   Perl, Orly ^a   Barda Saad, Mira ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CELL PROTEIN; CELL PROTEIN ADAP; CELL PROTEIN SLP76; NCK PROTEIN; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE PHOSPHATASE SHP; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; WISKOTT ALDRICH SYNDROME PROTEIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; HUMANS; ONCOGENE PROTEINS; PHOSPHOPROTEINS; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 79959396065     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01358-10     Document Type: Article

References (52)

1. Badour, K., et al. 2004. Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation. J. Exp. Med. 199:99-112.
2. Badour, K., et al. 2003. The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse. Immunity 18:141-154.
3. Badour, K., J. Zhang, and K. A. Siminovitch. 2004. Involvement of the Wiskott-Aldrich syndrome protein and other actin regulatory adaptors in T cell ctivation. Semin. Immunol. 16:395-407.
4. Barda-Saad, M., et al. 2005. Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton. Nat. Immunol. 6:80-89.
5. Barda-Saad, M., et al. 2010. Cooperative interactions at the SLP-76 complex are critical for actin polymerization. EMBO J. 29:2315-2328.
6. Barr, V. A., et al. 2006. T-cell antigen receptor-induced signaling complexes: internalization via a cholesterol-dependent endocytic pathway. Traffic :1143-1162.
7. Braiman, A., M. Barda-Saad, C. L. Sommers, and L. E. Samelson. 2006. Recruitment and activation of PLCgamma1 in T cells: a new insight into old omains. EMBO J. 25:774-784.
8. Bubeck Wardenburg, J., et al. 1998. Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. Immunity 9:607-616.
9. Bunnell, S. C., et al. 2002. T cell receptor ligation induces the formation of dynamically regulated signaling assemblies. J. Cell Biol. 158:1263-1275.
10. Burbach, B. J., R. B. Medeiros, K. L. Mueller, and Y. Shimizu. 2007. T-cell receptor signaling to integrins. Immunol. Rev. 218:65-81.
11. Cannon, J. L., et al. 2001. Wasp recruitment to the T cell:APC contact site occurs independently of Cdc42 activation. Immunity 15:249-259.
12. Charrin, S., and A. Alcover. 2006. Role of ERM (ezrin-radixin-moesin) proteins in T lymphocyte polarization, immune synapse formation and in T cell receptor-mediated signaling. Front. Biosci. 11:1987-1997.
13. Cory, G. O., R. Garg, R. Cramer, and A. J. Ridley. 2002. Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich syndrome protein. J. Biol. Chem. 277:45115-45121.
14. Custodio, N., M. Vivo, M. Antoniou, and M. Carmo-Fonseca. 2007. Splicingand cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site. J. Cell Biol. 179:199-207.
15. da Silva, A. J., et al. 1997. Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc. Natl. Acad. Sci. U. S. A. 94:7493-7498.
16. Dombroski, D., et al. 2005. Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton. J. Immunol. 174:1385-392.
17. Donnadieu, E., M. H. Jouvin, and J. P. Kinet. 2000. A second amplifier function for the allergy-associated Fc(epsilon)RI-beta subunit. Immunity 2:515-523.
18. Geng, L., S. Pfister, S. K. Kraeft, and C. E. Rudd. 2001. Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain. Proc. Natl. Acad. Sci. U. S. A. 98:11527-11532.
19. Geng, L., M. Raab, and C. E. Rudd. 1999. Cutting edge: SLP-76 cooperativity with FYB/FYN-T in the up-regulation of TCR-driven IL-2 transcription requires SLP-76 binding to FYB at Tyr595 and Tyr651. J. Immunol. 163: 5753-5757.
20. Gomez, T. S., et al. 2007. Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological ynapse. Immunity 26:177-190.
21. Gomez, T. S., et al. 2006. HS1 functions as an essential actin-regulatory adaptor protein at the immune synapse. Immunity 24:741-752.
22. Griffiths, E. K., et al. 2001. Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science 293:2260-2263.
23. Griffiths, E. K., and J. M. Penninger. 2002. Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap. Curr. Opin. mmunol. 14:317-322.
24. Huang, Y., et al. 2005. Deficiency of ADAP/Fyb/SLAP-130 destabilizes SKAP55 in Jurkat T cells. J. Biol. Chem. 280:23576-23583.
25. Jordan, M. S., A. L. Singer, and G. A. Koretzky. 2003. Adaptors as central mediators of signal transduction in immune cells. Nat. Immunol. 4:110-116.
26. Krause, M., et al. 2000. Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J. Cell Biol. 149:181-194.
27. Laurence, A., E. Astoul, S. Hanrahan, N. Totty, and D. Cantrell. 2004. Identification of pro-interleukin 16 as a novel target of MAP kinases in ctivated T lymphocytes. Eur. J. Immunol. 34:587-597.
28. Lettau, M., et al. 2010. The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes. Protein ci. 19:658-669.
29. Lettau, M., J. Pieper, and O. Janssen. 2009. Nck adapter proteins: functional versatility in T cells. Cell Commun. Signal. 7:1.
30. Mabon, S. A., and T. Misteli. 2005. Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo. PLoS Biol. 3:e374.
31. Miyoshi-Akiyama, T., L. M. Aleman, J. M. Smith, C. E. Adler, and B. J. Mayer. 2001. Regulation of Cbl phosphorylation by the Abl tyrosine kinase nd the Nck SH2/SH3 adaptor. Oncogene 20:4058-4069.
32. Musci, M. A., et al. 1997. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine inases. J. Biol. Chem. 272:11674-11677.
33. Nolz, J. C., et al. 2006. The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation. urr. Biol. 16:24-34.
34. Nolz, J. C., et al. 2007. WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse. Mol. Cell. Biol. 7:5986-6000.
35. Peterson, E. J. 2003. The TCR ADAPts to integrin-mediated cell adhesion. Immunol. Rev. 192:113-121.
36. Peterson, E. J., et al. 2001. Coupling of the TCR to integrin activation by Slap-130/Fyb. Science 293:2263-2265.
37. Samelson, L. E. 2002. Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins. Annu. Rev. Immunol. 20:371-394.
38. Sauer, K., et al. 2001. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-6 in lymphocytes. J. Biol. Chem. 276:45207-45216.
39. Schwartzberg, P. L. 2007. Formin the way. Immunity 26:139-141.
40. Sechi, A. S., J. Buer, J. Wehland, and M. Probst-Kepper. 2002. Changes in actin dynamics at the T-cell/APC interface: implications for T-cell anergy? mmunol. Rev. 189:98-110.
41. Shen, S., et al. 2009. The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in hymic selection and T-cell activation. Blood 114:74-84.
42. Singh, S., M. Plassmeyer, D. Gaur, and L. H. Miller. 2007. Mononeme: a new secretory organelle in Plasmodium falciparum merozoites identified by localization of rhomboid-1 protease. Proc. Natl. Acad. Sci. U. S. A. 104: 20043-20048.
43. Suzuki, J., S. Yamasaki, J. Wu, G. A. Koretzky, and T. Saito. 2007. The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation. Blood 109:168-175.
44. Torres, E., and M. K. Rosen. 2006. Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP. J. Biol. Chem. 281:3513-3520.
45. Wang, H., et al. 2004. ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC onjugation. J. Exp. Med. 200:1063-1074.
46. Wang, H., B. Wei, G. Bismuth, and C. E. Rudd. 2009. SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility. roc. Natl. Acad. Sci. U. S. A. 106:12436-12441.
47. Weiss, A. 2010. The right team at the right time to go for a home run: tyrosine kinase activation by the TCR. Nat. Immunol. 11:101-104.
48. Wu, J. N., and G. A. Koretzky. 2004. The SLP-76 family of adapter proteins. Semin. Immunol. 16:379-393.
49. Wunderlich, L., A. Farago, J. Downward, and L. Buday. 1999. Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes. ur. J. Immunol. 29:1068-1075.
50. Zacharias, D. A., J. D. Violin, A. C. Newton, and R. Y. Tsien. 2002. Partitioning of lipid-modified monomeric GFPs into membrane microdomains of ive cells. Science 296:913-916.
51. Zeng, R., et al. 2003. SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site J. Immunol. 171:1360-1368.
52. Zipfel, P. A., et al. 2006. Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr. Biol. 6:35-46.