메뉴 건너뛰기




Volumn 9, Issue 9, 2014, Pages 847-862

The role of macrophages in influenza A virus infection

Author keywords

alveolar macrophage; infection; influenza A virus; lung; macrophage

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RANTES; TUMOR NECROSIS FACTOR ALPHA;

EID: 84908248922     PISSN: 17460794     EISSN: 17460808     Source Type: Journal    
DOI: 10.2217/fvl.14.65     Document Type: Review
Times cited : (27)

References (146)
  • 2
    • 0037425564 scopus 로고    scopus 로고
    • Mortality associated with infuenza and respiratory syncytial virus in the United States
    • Thompson W W, Shay DK, Weintraub E et al. Mortality associated with infuenza and respiratory syncytial virus in the United States. JAMA 289(2), 179-186 (2003).
    • (2003) JAMA , vol.289 , Issue.2 , pp. 179-186
    • Thompson, W.W.1    Shay, D.K.2    Weintraub, E.3
  • 3
    • 4544332903 scopus 로고    scopus 로고
    • Infuenza-associated hospitalizations in the United States
    • Thompson W W, Shay DK, Weintraub E et al. Infuenza-associated hospitalizations in the United States. JAMA 292(11), 1333-1340 (2004).
    • (2004) JAMA , vol.292 , Issue.11 , pp. 1333-1340
    • Thompson, W.W.1    Shay, D.K.2    Weintraub, E.3
  • 4
    • 84860245317 scopus 로고    scopus 로고
    • Hospitalizations associated with infuenza and respiratory syncytial virus in the United States, 1993-2008
    • Zhou H, Thompson W W, Viboud CG et al. Hospitalizations associated with infuenza and respiratory syncytial virus in the United States, 1993-2008. Clin. Infect. Dis. 54(10), 1427-1436 (2012).
    • (2012) Clin. Infect. Dis. , vol.54 , Issue.10 , pp. 1427-1436
    • Zhou, H.1    Thompson, W.W.2    Viboud, C.G.3
  • 5
    • 70449854577 scopus 로고    scopus 로고
    • Innate immune responses to infuenza A H5N1: Friend or foe?
    • Peiris JS, Cheung CY, Leung CY, Nicholls JM. Innate immune responses to infuenza A H5N1: friend or foe? Trends Immunol. 30(12), 574-584 (2009).
    • (2009) Trends Immunol. , vol.30 , Issue.12 , pp. 574-584
    • Peiris, J.S.1    Cheung, C.Y.2    Leung, C.Y.3    Nicholls, J.M.4
  • 6
    • 27744598497 scopus 로고    scopus 로고
    • Pathogenicity of infuenza viruses with genes from the 1918 pandemic virus: Functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice
    • Tumpey TM, Garcia-Sastre A, Taubenberger JK et al. Pathogenicity of infuenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. J. Virol. 79(23), 14933-14944 (2005).
    • (2005) J. Virol. , vol.79 , Issue.23 , pp. 14933-14944
    • Tumpey, T.M.1    Garcia-Sastre, A.2    Taubenberger, J.K.3
  • 7
    • 33947417049 scopus 로고    scopus 로고
    • Role of host cytokine responses in the pathogenesis of avian H5N1 infuenza viruses in mice
    • Szretter KJ, Gangappa S, Lu X et al. Role of host cytokine responses in the pathogenesis of avian H5N1 infuenza viruses in mice. J. Virol. 81(6), 2736-2744 (2007).
    • (2007) J. Virol. , vol.81 , Issue.6 , pp. 2736-2744
    • Szretter, K.J.1    Gangappa, S.2    Lu, X.3
  • 8
    • 25444432780 scopus 로고    scopus 로고
    • Avian infuenza A (H5N1) infection in humans
    • Beigel JH, Farrar J, Han AM et al. Avian infuenza A (H5N1) infection in humans. N. Engl. J. Med. 353(13), 1374-1385 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , Issue.13 , pp. 1374-1385
    • Beigel, J.H.1    Farrar, J.2    Han, A.M.3
  • 9
    • 84884470169 scopus 로고    scopus 로고
    • Differential host response, rather than early viral replication effciency, correlates with pathogenicity caused by infuenza viruses
    • Askovich PS, Sanders CJ, Rosenberger CM et al. Differential host response, rather than early viral replication effciency, correlates with pathogenicity caused by infuenza viruses. PLoS ONE 8(9), e74863 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.9 , pp. e74863
    • Askovich, P.S.1    Sanders, C.J.2    Rosenberger, C.M.3
  • 10
    • 0026764722 scopus 로고
    • Infuenza: Pathogenesis and host defense
    • Bender BS, Small PA Jr. Infuenza: pathogenesis and host defense. Semin. Respir. Infect. 7(1), 38-45 (1992).
    • (1992) Semin. Respir. Infect. , vol.7 , Issue.1 , pp. 38-45
    • Bender, B.S.1    Small, P.A.2
  • 11
    • 0019962775 scopus 로고
    • Infuenza virus replication in human alveolar macrophages
    • Rodgers BC, Mims CA. Infuenza virus replication in human alveolar macrophages. J. Med. Virol. 9(3), 177-184 (1982).
    • (1982) J. Med. Virol. , vol.9 , Issue.3 , pp. 177-184
    • Rodgers, B.C.1    Mims, C.A.2
  • 12
    • 0036244434 scopus 로고    scopus 로고
    • Macrophage defences against respiratory tract infections
    • Gordon SB, Read RC. Macrophage defences against respiratory tract infections. Br. Med. Bull. 61, 45-61 (2002).
    • (2002) Br. Med. Bull. , vol.61 , pp. 45-61
    • Gordon, S.B.1    Read, R.C.2
  • 13
    • 80052472550 scopus 로고    scopus 로고
    • Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury
    • Janssen WJ, Barthel L, Muldrow A et al. Fas determines differential fates of resident and recruited macrophages during resolution of acute lung injury. Am. J. Respir. Crit. Care Med. 184(5), 547-560 (2011).
    • (2011) Am. J. Respir. Crit. Care Med. , vol.184 , Issue.5 , pp. 547-560
    • Janssen, W.J.1    Barthel, L.2    Muldrow, A.3
  • 14
    • 33746817535 scopus 로고    scopus 로고
    • Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung infammation
    • Maus UA, Janzen S, Wall G et al. Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung infammation. Am. J. Respir. Cell Mol. Biol. 35(2), 227-235 (2006).
    • (2006) Am. J. Respir. Cell Mol. Biol. , vol.35 , Issue.2 , pp. 227-235
    • Maus, U.A.1    Janzen, S.2    Wall, G.3
  • 16
    • 84872765982 scopus 로고    scopus 로고
    • Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
    • Yona S, Kim KW, Wolf Y et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 38(1), 79-91 (2013).
    • (2013) Immunity , vol.38 , Issue.1 , pp. 79-91
    • Yona, S.1    Kim, K.W.2    Wolf, Y.3
  • 17
    • 35748957798 scopus 로고    scopus 로고
    • Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages
    • Landsman L, Jung S. Lung macrophages serve as obligatory intermediate between blood monocytes and alveolar macrophages. J. Immunol. 179(6), 3488-3494 (2007).
    • (2007) J. Immunol. , vol.179 , Issue.6 , pp. 3488-3494
    • Landsman, L.1    Jung, S.2
  • 18
    • 84876775203 scopus 로고    scopus 로고
    • Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
    • Hashimoto D, Chow A, Noizat C et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38(4), 792-804 (2013).
    • (2013) Immunity , vol.38 , Issue.4 , pp. 792-804
    • Hashimoto, D.1    Chow, A.2    Noizat, C.3
  • 20
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3(1), 23-35 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 21
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: Time for reassessment
    • Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep. 6, 13 (2014).
    • (2014) F1000Prime Rep. , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 22
    • 84872794136 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization
    • Spence S, Fitzsimons A, Boyd CR et al. Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. Immunity 38(1), 66-78 (2013).
    • (2013) Immunity , vol.38 , Issue.1 , pp. 66-78
    • Spence, S.1    Fitzsimons, A.2    Boyd, C.R.3
  • 23
    • 57149092384 scopus 로고    scopus 로고
    • Infuenza A virus inhibits type i IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression
    • Pauli EK, Schmolke M, Wolff T et al Infuenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression. PLoS Pathog. 4(11), e1000196 (2008).
    • (2008) PLoS Pathog. , vol.4 , Issue.11 , pp. e1000196
    • Pauli, E.K.1    Schmolke, M.2    Wolff, T.3
  • 24
    • 42149119018 scopus 로고    scopus 로고
    • Cutting edge: Innate immune response triggered by infuenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway
    • Pothlichet J, Chignard M, Si-Tahar M. Cutting edge: innate immune response triggered by infuenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-dependent pathway. J. Immunol. 180(4), 2034-2038 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.4 , pp. 2034-2038
    • Pothlichet, J.1    Chignard, M.2    Si-Tahar, M.3
  • 25
    • 84863290608 scopus 로고    scopus 로고
    • Innate immune response of human alveolar macrophages during infuenza A infection
    • Wang J, Nikrad MP, Travanty EA et al. Innate immune response of human alveolar macrophages during infuenza A infection. PLoS ONE 7(3), e29879 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. e29879
    • Wang, J.1    Nikrad, M.P.2    Travanty, E.A.3
  • 27
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat. Rev. Immunol. 5(12), 953-964 (2005).
    • (2005) Nat. Rev. Immunol. , vol.5 , Issue.12 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 28
    • 79951897946 scopus 로고    scopus 로고
    • Innate Immunity to intracellular pathogens: Macrophage receptors and responses to microbial entry
    • Pluddemann A, Mukhopadhyay S, Gordon S. Innate Immunity to intracellular pathogens: macrophage receptors and responses to microbial entry. Immunol. Rev. 240(1), 11-24 (2011).
    • (2011) Immunol. Rev. , vol.240 , Issue.1 , pp. 11-24
    • Pluddemann, A.1    Mukhopadhyay, S.2    Gordon, S.3
  • 29
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: Mechanism and functions
    • Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity 32(5), 593-604 (2010).
    • (2010) Immunity , vol.32 , Issue.5 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 30
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 27, 451-483 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 31
    • 33745067210 scopus 로고    scopus 로고
    • IL-10-producing macrophages preferentially clear early apoptotic cells
    • Xu W, Roos A, Schlagwein N, Woltman AM, Daha MR, Van Kooten C. IL-10-producing macrophages preferentially clear early apoptotic cells. Blood 107(12), 4930-4937 (2006).
    • (2006) Blood , vol.107 , Issue.12 , pp. 4930-4937
    • Xu, W.1    Roos, A.2    Schlagwein, N.3    Woltman, A.M.4    Daha, M.R.5    Van Kooten, C.6
  • 32
    • 33646455658 scopus 로고    scopus 로고
    • Phenotypic and functional profling of human proinfammatory type-1 and anti-infammatory type-2 macrophages in response to microbial antigens and IFN-gamma-and CD40L-mediated costimulation
    • Verreck FA, De Boer T, Langenberg DM, Van Der Zanden L, Ottenhoff TH. Phenotypic and functional profling of human proinfammatory type-1 and anti-infammatory type-2 macrophages in response to microbial antigens and IFN-gamma-and CD40L-mediated costimulation. J. Leukoc. Biol. 79(2), 285-293 (2006).
    • (2006) J. Leukoc. Biol. , vol.79 , Issue.2 , pp. 285-293
    • Verreck, F.A.1    De Boer, T.2    Langenberg, D.M.3    Van Der Zanden, L.4    Ottenhoff, T.H.5
  • 33
    • 0021338409 scopus 로고
    • The accessory cell function of human alveolar macrophages in specifc T cell proliferation
    • Toews GB, Vial WC, Dunn MM et al. The accessory cell function of human alveolar macrophages in specifc T cell proliferation. J. Immunol. 132(1), 181-186 (1984).
    • (1984) J. Immunol. , vol.132 , Issue.1 , pp. 181-186
    • Toews, G.B.1    Vial, W.C.2    Dunn, M.M.3
  • 34
    • 70149110900 scopus 로고    scopus 로고
    • Smoking-dependent reprogramming of alveolar macrophage polarization: Implication for pathogenesis of chronic obstructive pulmonary disease
    • Shaykhiev R, Krause A, Salit J et al. Smoking-dependent reprogramming of alveolar macrophage polarization: implication for pathogenesis of chronic obstructive pulmonary disease. J. Immunol. 183 (4), 2867-2883 (2009).
    • (2009) J. Immunol. , vol.183 , Issue.4 , pp. 2867-2883
    • Shaykhiev, R.1    Krause, A.2    Salit, J.3
  • 35
    • 77951634926 scopus 로고    scopus 로고
    • Macrophages: Regulators of sex differences in asthma?
    • Melgert BN, Oriss TB, Qi Z et al. Macrophages: regulators of sex differences in asthma? Am. J. Respir. Cell Mol. Biol. 42(5), 595-603 (2010).
    • (2010) Am. J. Respir. Cell Mol. Biol. , vol.42 , Issue.5 , pp. 595-603
    • Melgert, B.N.1    Oriss, T.B.2    Qi, Z.3
  • 36
    • 77956618333 scopus 로고    scopus 로고
    • Alternatively activated alveolar macrophages in pulmonary fbrosis-mediator production and intracellular signal transduction
    • Pechkovsky DV, Prasse A, Kollert F et al. Alternatively activated alveolar macrophages in pulmonary fbrosis-mediator production and intracellular signal transduction. Clin. Immunol. 137(1), 89-101 (2010).
    • (2010) Clin. Immunol. , vol.137 , Issue.1 , pp. 89-101
    • Pechkovsky, D.V.1    Prasse, A.2    Kollert, F.3
  • 38
    • 78651062856 scopus 로고    scopus 로고
    • Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice
    • Liu G, Ma H, Qiu L et al. Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol. Cell Biol. 89(1), 130-142 (2011).
    • (2011) Immunol. Cell Biol. , vol.89 , Issue.1 , pp. 130-142
    • Liu, G.1    Ma, H.2    Qiu, L.3
  • 39
    • 84863085638 scopus 로고    scopus 로고
    • Adherent human alveolar macrophages exhibit a transient pro-infammatory profle that confounds responses to innate immune stimulation
    • Tomlinson GS, Booth H, Petit SJ et al. Adherent human alveolar macrophages exhibit a transient pro-infammatory profle that confounds responses to innate immune stimulation. PLoS ONE 7(6), e40348 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.6 , pp. e40348
    • Tomlinson, G.S.1    Booth, H.2    Petit, S.J.3
  • 40
    • 84862104611 scopus 로고    scopus 로고
    • Defning GM-CSF-and macrophage-CSF-dependent macrophage responses by in vitro models
    • Lacey DC, Achuthan A, Fleetwood AJ et al. Defning GM-CSF-and macrophage-CSF-dependent macrophage responses by in vitro models. J. Immunol. 188(11), 5752-5765 (2012).
    • (2012) J. Immunol. , vol.188 , Issue.11 , pp. 5752-5765
    • Lacey, D.C.1    Achuthan, A.2    Fleetwood, A.J.3
  • 41
    • 0034748924 scopus 로고    scopus 로고
    • GM-CSF regulates alveolar macrophage differentiation and innate Immunity in the lung through PU.1
    • Shibata Y, Berclaz PY, Chroneos ZC, Yoshida M, Whitsett JA, Trapnell BC. GM-CSF regulates alveolar macrophage differentiation and innate Immunity in the lung through PU.1. Immunity 15(4), 557-567 (2001).
    • (2001) Immunity , vol.15 , Issue.4 , pp. 557-567
    • Shibata, Y.1    Berclaz, P.Y.2    Chroneos, Z.C.3    Yoshida, M.4    Whitsett, J.A.5    Trapnell, B.C.6
  • 42
    • 0036201268 scopus 로고    scopus 로고
    • GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense
    • Trapnell BC, Whitsett JA. GM-CSF regulates pulmonary surfactant homeostasis and alveolar macrophage-mediated innate host defense. Annu. Rev. Physiol. 64, 775-802 (2002).
    • (2002) Annu. Rev. Physiol. , vol.64 , pp. 775-802
    • Trapnell, B.C.1    Whitsett, J.A.2
  • 43
    • 77954073077 scopus 로고    scopus 로고
    • Protective effects of recombinant human granulocyte macrophage colony stimulating factor on H1N1 infuenza virus-induced pneumonia in mice
    • Huang H, Li H, Zhou P, Ju D. Protective effects of recombinant human granulocyte macrophage colony stimulating factor on H1N1 infuenza virus-induced pneumonia in mice. Cytokine 51(2), 151-157 (2010).
    • (2010) Cytokine , vol.51 , Issue.2 , pp. 151-157
    • Huang, H.1    Li, H.2    Zhou, P.3    Ju, D.4
  • 44
    • 80051553380 scopus 로고    scopus 로고
    • GM-CSF in the lung protects against lethal infuenza infection
    • Huang FF, Barnes PF, Feng Y et al. GM-CSF in the lung protects against lethal infuenza infection. Am. J. Respir. Crit. Care Med. 184(2), 259-268 (2011).
    • (2011) Am. J. Respir. Crit. Care Med. , vol.184 , Issue.2 , pp. 259-268
    • Huang, F.F.1    Barnes, P.F.2    Feng, Y.3
  • 45
    • 84863616475 scopus 로고    scopus 로고
    • Distinct macrophage subpopulations characterize acute infection and chronic infammatory lung disease
    • Duan M, Li WC, Vlahos R, Maxwell MJ, Anderson GP, Hibbs ML. Distinct macrophage subpopulations characterize acute infection and chronic infammatory lung disease. J. Immunol. 189(2), 946-955 (2012).
    • (2012) J. Immunol. , vol.189 , Issue.2 , pp. 946-955
    • Duan, M.1    Li, W.C.2    Vlahos, R.3    Maxwell, M.J.4    Anderson, G.P.5    Hibbs, M.L.6
  • 46
    • 0037154274 scopus 로고    scopus 로고
    • Stereotyped and specifc gene expression programs in human innate immune responses to bacteria
    • Boldrick JC, Alizadeh AA, Diehn M et al. Stereotyped and specifc gene expression programs in human innate immune responses to bacteria. Proc. Natl Acad. Sci. USA 99(2), 972-977 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , Issue.2 , pp. 972-977
    • Boldrick, J.C.1    Alizadeh, A.A.2    Diehn, M.3
  • 47
    • 84881492566 scopus 로고    scopus 로고
    • Identifcation of myeloid cell subsets in murine lungs using fow cytometry
    • Zaynagetdinov R, Sherrill TP, Kendall PL et al. Identifcation of myeloid cell subsets in murine lungs using fow cytometry. Am. J. Respir. Cell Mol. Biol. 49(2), 180-189 (2013).
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.49 , Issue.2 , pp. 180-189
    • Zaynagetdinov, R.1    Sherrill, T.P.2    Kendall, P.L.3
  • 48
    • 33646819034 scopus 로고    scopus 로고
    • Specifc aspects of fow cytometric analysis of cells from the lung
    • Garn H. Specifc aspects of fow cytometric analysis of cells from the lung. Exp. Toxicol. Pathol. 57(Suppl. 2), 21-24 (2006).
    • (2006) Exp. Toxicol. Pathol. , vol.57 , pp. 21-24
    • Garn, H.1
  • 49
    • 0027191388 scopus 로고
    • Separation of alveolar macrophages and dendritic cells via autofuorescence: Phenotypical and functional characterization
    • Havenith CE, Breedijk AJ, Van Miert PP et al. Separation of alveolar macrophages and dendritic cells via autofuorescence: phenotypical and functional characterization. J. Leukoc. Biol. 53(5), 504-510 (1993).
    • (1993) J. Leukoc. Biol. , vol.53 , Issue.5 , pp. 504-510
    • Havenith, C.E.1    Breedijk, A.J.2    Van Miert, P.P.3
  • 50
    • 33846414364 scopus 로고    scopus 로고
    • Distinct differentiation potential of blood monocyte subsets in the lung
    • Landsman L, Varol C, Jung S. Distinct differentiation potential of blood monocyte subsets in the lung. J. Immunol. 178 (4), 2000-2007 (2007).
    • (2007) J. Immunol. , vol.178 , Issue.4 , pp. 2000-2007
    • Landsman, L.1    Varol, C.2    Jung, S.3
  • 51
    • 0034892257 scopus 로고    scopus 로고
    • Functional heterogeneity in liver and lung macrophages
    • Laskin DL, Weinberger B, Laskin JD. Functional heterogeneity in liver and lung macrophages. J. Leukoc. Biol. 70(2), 163-170 (2001).
    • (2001) J. Leukoc. Biol. , vol.70 , Issue.2 , pp. 163-170
    • Laskin, D.L.1    Weinberger, B.2    Laskin, J.D.3
  • 52
    • 0021840276 scopus 로고
    • Autofuorescence of alveolar macrophages: Problems and potential solutions
    • Edelson JD, MacFadden DK, Klein M, Rebuck AS. Autofuorescence of alveolar macrophages: problems and potential solutions. Med. Hypotheses 17(4), 403-407 (1985).
    • (1985) Med. Hypotheses , vol.17 , Issue.4 , pp. 403-407
    • Edelson, J.D.1    MacFadden, D.K.2    Klein, M.3    Rebuck, A.S.4
  • 53
    • 0343488841 scopus 로고    scopus 로고
    • Analysis of single and double-stained alveolar macrophages by fow cytometry
    • Weyde J, Wassermann K, Schell-Frederick E. Analysis of single and double-stained alveolar macrophages by fow cytometry. J. Immunol. Methods 207(2), 115-123 (1997).
    • (1997) J. Immunol. Methods , vol.207 , Issue.2 , pp. 115-123
    • Weyde, J.1    Wassermann, K.2    Schell-Frederick, E.3
  • 54
    • 84880666005 scopus 로고    scopus 로고
    • Depletion of alveolar macrophages during infuenza infection facilitates bacterial superinfections
    • Ghoneim HE, Thomas PG, Mccullers JA. Depletion of alveolar macrophages during infuenza infection facilitates bacterial superinfections. J. Immunol. 191(3), 1250-1259 (2013).
    • (2013) J. Immunol. , vol.191 , Issue.3 , pp. 1250-1259
    • Ghoneim, H.E.1    Thomas, P.G.2    McCullers, J.A.3
  • 55
    • 84863649352 scopus 로고    scopus 로고
    • Innate immune induction and infuenza protection elicited by a response-selective agonist of human C5a
    • Sanderson SD, Thoman ML, Kis K et al. Innate immune induction and infuenza protection elicited by a response-selective agonist of human C5a. PLoS ONE 7(7), e40303 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.7 , pp. e40303
    • Sanderson, S.D.1    Thoman, M.L.2    Kis, K.3
  • 56
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: Development, heterogeneity, and relationship with dendritic cells
    • Auffray C, Sieweke MH, Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu. Rev. Immunol. 27, 669-692 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 57
    • 84900404514 scopus 로고    scopus 로고
    • Overexpression of CD163, CD204 and CD206 on alveolar macrophages in the lungs of patients with severe chronic obstructive pulmonary disease
    • Kaku Y, Imaoka H, Morimatsu Y et al. Overexpression of CD163, CD204 and CD206 on alveolar macrophages in the lungs of patients with severe chronic obstructive pulmonary disease. PLoS ONE 9(1), e87400 (2014).
    • (2014) PLoS ONE , vol.9 , Issue.1 , pp. e87400
    • Kaku, Y.1    Imaoka, H.2    Morimatsu, Y.3
  • 58
    • 0032529409 scopus 로고    scopus 로고
    • Identifcation of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163)
    • Hogger P, Dreier J, Droste A, Buck F, Sorg C. Identifcation of the integral membrane protein RM3/1 on human monocytes as a glucocorticoid-inducible member of the scavenger receptor cysteine-rich family (CD163). J. Immunol. 161(4), 1883-1890 (1998).
    • (1998) J. Immunol. , vol.161 , Issue.4 , pp. 1883-1890
    • Hogger, P.1    Dreier, J.2    Droste, A.3    Buck, F.4    Sorg, C.5
  • 59
    • 0033082935 scopus 로고    scopus 로고
    • Other functions, other genes: Alternative activation of antigen-presenting cells
    • Goerdt S, Orfanos CE. Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 10(2), 137-142 (1999).
    • (1999) Immunity , vol.10 , Issue.2 , pp. 137-142
    • Goerdt, S.1    Orfanos, C.E.2
  • 60
    • 78650001430 scopus 로고    scopus 로고
    • Evolution of CD33-related siglecs: Regulating host immune functions and escaping pathogen exploitation?
    • Cao H, Crocker PR. Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation? Immunology 132(1), 18-26 (2010).
    • (2010) Immunology , vol.132 , Issue.1 , pp. 18-26
    • Cao, H.1    Crocker, P.R.2
  • 61
    • 84863423145 scopus 로고    scopus 로고
    • Expression and preliminary functional analysis of Siglec-F on mouse macrophages
    • Feng YH, Mao H. Expression and preliminary functional analysis of Siglec-F on mouse macrophages. J. Zhejiang Univ. Sci. B. 13 (5), 386-394 (2012).
    • (2012) J. Zhejiang Univ. Sci. B. , vol.13 , Issue.5 , pp. 386-394
    • Feng, Y.H.1    Mao, H.2
  • 62
    • 84878548127 scopus 로고    scopus 로고
    • Macrophage-expressed IFN-beta contributes to apoptotic alveolar epithelial cell injury in severe infuenza virus pneumonia
    • Hogner K, Wolff T, Pleschka S et al. Macrophage-expressed IFN-beta contributes to apoptotic alveolar epithelial cell injury in severe infuenza virus pneumonia. PLoS Pathog. 9(2), e1003188 (2013).
    • (2013) PLoS Pathog. , vol.9 , Issue.2 , pp. e1003188
    • Hogner, K.1    Wolff, T.2    Pleschka, S.3
  • 63
    • 0027272534 scopus 로고
    • Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
    • Fleming TJ, Fleming ML, Malek TR. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151(5), 2399-2408 (1993).
    • (1993) J. Immunol. , vol.151 , Issue.5 , pp. 2399-2408
    • Fleming, T.J.1    Fleming, M.L.2    Malek, T.R.3
  • 64
    • 1942502280 scopus 로고    scopus 로고
    • Absence of cross-reactivity between murine Ly-6C and Ly-6G
    • Nagendra S, Schlueter AJ. Absence of cross-reactivity between murine Ly-6C and Ly-6G. Cytometry A 58(2), 195-200 (2004).
    • (2004) Cytometry A , vol.58 , Issue.2 , pp. 195-200
    • Nagendra, S.1    Schlueter, A.J.2
  • 65
    • 50049100345 scopus 로고    scopus 로고
    • A critical function for CD200 in lung immune homeostasis and the severity of infuenza infection
    • Snelgrove RJ, Goulding J, Didierlaurent AM et al. A critical function for CD200 in lung immune homeostasis and the severity of infuenza infection. Nat. Immunol. 9(9), 1074-1083 (2008).
    • (2008) Nat. Immunol. , vol.9 , Issue.9 , pp. 1074-1083
    • Snelgrove, R.J.1    Goulding, J.2    Didierlaurent, A.M.3
  • 66
    • 77949571347 scopus 로고    scopus 로고
    • Expression of the inhibitory CD200 receptor is associated with alternative macrophage activation
    • Koning N, Van Eijk M, Pouwels W et al. Expression of the inhibitory CD200 receptor is associated with alternative macrophage activation. J. Innate Immun. 2(2), 195-200 (2010).
    • (2010) J. Innate Immun. , vol.2 , Issue.2 , pp. 195-200
    • Koning, N.1    Van Eijk, M.2    Pouwels, W.3
  • 68
    • 67349129413 scopus 로고    scopus 로고
    • Analysis of sialoadhesin expression on mouse alveolar macrophages
    • Ducreux J, Crocker PR, Vanbever R. Analysis of sialoadhesin expression on mouse alveolar macrophages. Immunol. Lett. 124(2), 77-80 (2009).
    • (2009) Immunol. Lett. , vol.124 , Issue.2 , pp. 77-80
    • Ducreux, J.1    Crocker, P.R.2    Vanbever, R.3
  • 69
    • 84892550193 scopus 로고    scopus 로고
    • Increased expression of Siglec-1 on peripheral blood monocytes and its role in mononuclear cell reactivity to autoantigen in rheumatoid arthritis
    • Xiong YS, Cheng Y, Lin QS et al. Increased expression of Siglec-1 on peripheral blood monocytes and its role in mononuclear cell reactivity to autoantigen in rheumatoid arthritis. Rheumatology (Oxford) 53(2), 250-259 (2014).
    • (2014) Rheumatology (Oxford) , vol.53 , Issue.2 , pp. 250-259
    • Xiong, Y.S.1    Cheng, Y.2    Lin, Q.S.3
  • 70
    • 43249118968 scopus 로고    scopus 로고
    • Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from infuenza infection
    • Sun K, Metzger DW. Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from infuenza infection. Nat. Med. 14(5), 558-564 (2008).
    • (2008) Nat. Med. , vol.14 , Issue.5 , pp. 558-564
    • Sun, K.1    Metzger, D.W.2
  • 71
    • 0037307026 scopus 로고    scopus 로고
    • A macrophage colony-stimulating factor receptor-green fuorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
    • Sasmono RT, Oceandy D, Pollard JW et al. A macrophage colony-stimulating factor receptor-green fuorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 101(3), 1155-1163 (2003).
    • (2003) Blood , vol.101 , Issue.3 , pp. 1155-1163
    • Sasmono, R.T.1    Oceandy, D.2    Pollard, J.W.3
  • 72
    • 84856299316 scopus 로고    scopus 로고
    • Generation and characterization of MacGreen mice, the Cfs1r-EGFP transgenic mice
    • Sasmono RT, Williams E. Generation and characterization of MacGreen mice, the Cfs1r-EGFP transgenic mice. Methods Mol. Biol. 844, 157-176 (2012).
    • (2012) Methods Mol. Biol. , vol.844 , pp. 157-176
    • Sasmono, R.T.1    Williams, E.2
  • 73
    • 34347405754 scopus 로고    scopus 로고
    • Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specifc transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1
    • Sasmono RT, Ehrnsperger A, Cronau SL et al. Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specifc transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1. J. Leukoc. Biol. 82(1), 111-123 (2007).
    • (2007) J. Leukoc. Biol. , vol.82 , Issue.1 , pp. 111-123
    • Sasmono, R.T.1    Ehrnsperger, A.2    Cronau, S.L.3
  • 74
    • 84901379724 scopus 로고    scopus 로고
    • Alveolar macrophages are rssential for protection from respiratory failure and associated morbidity following infuenza virus infection
    • Schneider C, Nobs SP, Heer AK et al. Alveolar macrophages are rssential for protection from respiratory failure and associated morbidity following infuenza virus infection. PLoS Pathog. 10(4), e1004053 (2014).
    • (2014) PLoS Pathog. , vol.10 , Issue.4 , pp. e1004053
    • Schneider, C.1    Nobs, S.P.2    Heer, A.K.3
  • 75
    • 84904392481 scopus 로고    scopus 로고
    • Transient ablation of alveolar macrophages leads to massive pathology of infuenza infection without affecting cellular adaptive immunity Eur
    • Purnama C, Ng SL, Tetlak P et al. Transient ablation of alveolar macrophages leads to massive pathology of infuenza infection without affecting cellular adaptive immunity Eur. J. Immunol. 44(7), 2003-2012 (2014).
    • (2014) J. Immunol. , vol.44 , Issue.7 , pp. 2003-2012
    • Purnama, C.1    Ng, S.L.2    Tetlak, P.3
  • 76
  • 77
    • 84893652705 scopus 로고    scopus 로고
    • Alveolar macrophages: Plasticity in a tissue-specifc context
    • Hussell T, Bell TJ. Alveolar macrophages: plasticity in a tissue-specifc context. Nat. Rev. Immunol. 14(2), 81-93 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , Issue.2 , pp. 81-93
    • Hussell, T.1    Bell, T.J.2
  • 78
    • 33645278326 scopus 로고    scopus 로고
    • Avian fu: Infuenza virus receptors in the human airway
    • Shinya K, Ebina M, Yamada S, Ono M, Kasai N, Kawaoka Y Avian fu: infuenza virus receptors in the human airway. Nature 440(7083), 435-436 (2006).
    • (2006) Nature , vol.440 , Issue.7083 , pp. 435-436
    • Shinya, K.1    Ebina, M.2    Yamada, S.3    Ono, M.4    Kasai, N.5    Kawaoka, Y.6
  • 79
    • 0027302926 scopus 로고
    • Infuenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; The role of the host cell in selection of hemagglutinin receptor specifcity
    • Couceiro JN, Paulson JC, Baum LG. Infuenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specifcity. Virus Res. 29(2), 155-165 (1993).
    • (1993) Virus Res. , vol.29 , Issue.2 , pp. 155-165
    • Couceiro, J.N.1    Paulson, J.C.2    Baum, L.G.3
  • 80
    • 33645972581 scopus 로고    scopus 로고
    • H5N1 virus attachment to lower respiratory tract
    • Van Riel D, Munster VJ, De Wit E et al. H5N1 virus attachment to lower respiratory tract. Science 312(5772), 399 (2006).
    • (2006) Science , vol.312 , Issue.5772 , pp. 399
    • Van Riel, D.1    Munster, V.J.2    De Wit, E.3
  • 81
    • 68849120459 scopus 로고    scopus 로고
    • Sialic acid and receptor expression on the respiratory tract in normal subjects and H5N1 and non-avian infuenza patients
    • Nicholls JM, Peiris JS, Guan Y. Sialic acid and receptor expression on the respiratory tract in normal subjects and H5N1 and non-avian infuenza patients. Hong Kong Med. J. 15(3 Suppl. 4), 16-20 (2009).
    • (2009) Hong Kong Med. J. , vol.15 , Issue.3 , pp. 16-20
    • Nicholls, J.M.1    Peiris, J.S.2    Guan, Y.3
  • 82
    • 38049093537 scopus 로고    scopus 로고
    • Sialic acid receptor detection in the human respiratory tract: Evidence for widespread distribution of potential binding sites for human and avian infuenza viruses
    • Nicholls JM, Bourne AJ, Chen H, Guan Y, Peiris JS. Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian infuenza viruses. Respir. Res. 8, 73 (2007).
    • (2007) Respir. Res. , vol.8 , pp. 73
    • Nicholls, J.M.1    Bourne, A.J.2    Chen, H.3    Guan, Y.4    Peiris, J.S.5
  • 83
    • 33746215109 scopus 로고    scopus 로고
    • Infuenza virus receptor specifcity and cell tropism in mouse and human airway epithelial cells
    • Ibricevic A, Pekosz A, Walter MJ et al. Infuenza virus receptor specifcity and cell tropism in mouse and human airway epithelial cells. J. Virol. 80(15), 7469-7480 (2006).
    • (2006) J. Virol. , vol.80 , Issue.15 , pp. 7469-7480
    • Ibricevic, A.1    Pekosz, A.2    Walter, M.J.3
  • 84
    • 78951488037 scopus 로고    scopus 로고
    • Receptor binding profles of avian infuenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential
    • Shelton H, Ayora-Talavera G, Ren J et al. Receptor binding profles of avian infuenza virus hemagglutinin subtypes on human cells as a predictor of pandemic potential. J. Virol. 85(4), 1875-1880 (2011).
    • (2011) J. Virol. , vol.85 , Issue.4 , pp. 1875-1880
    • Shelton, H.1    Ayora-Talavera, G.2    Ren, J.3
  • 86
    • 84884550593 scopus 로고    scopus 로고
    • Receptor specifcity does not affect replication or virulence of the 2009 pandemic H1N1 infuenza virus in mice and ferrets
    • Lakdawala SS, Shih AR, Jayaraman A et al. Receptor specifcity does not affect replication or virulence of the 2009 pandemic H1N1 infuenza virus in mice and ferrets. Virology 446(1-2), 349-356 (2013).
    • (2013) Virology , vol.446 , Issue.1-2 , pp. 349-356
    • Lakdawala, S.S.1    Shih, A.R.2    Jayaraman, A.3
  • 87
    • 84863464103 scopus 로고    scopus 로고
    • Cell-surface receptors on macrophages and dendritic cells for attachment and entry of infuenza virus
    • Londrigan SL, Tate MD, Brooks AG, Reading PC. Cell-surface receptors on macrophages and dendritic cells for attachment and entry of infuenza virus. J. Leukoc. Biol. 92(1), 97-106 (2012).
    • (2012) J. Leukoc. Biol. , vol.92 , Issue.1 , pp. 97-106
    • Londrigan, S.L.1    Tate, M.D.2    Brooks, A.G.3    Reading, P.C.4
  • 88
    • 0034063448 scopus 로고    scopus 로고
    • Involvement of the mannose receptor in infection of macrophages by infuenza virus
    • Reading PC, Miller JL, Anders EM. Involvement of the mannose receptor in infection of macrophages by infuenza virus. J. Virol. 74 (11), 5190-5197 (2000).
    • (2000) J. Virol. , vol.74 , Issue.11 , pp. 5190-5197
    • Reading, P.C.1    Miller, J.L.2    Anders, E.M.3
  • 89
    • 77950479967 scopus 로고    scopus 로고
    • Macrophage receptors for infuenza A virus: Role of the macrophage galactose-type lectin and mannose receptor in viral entry
    • Upham JP, Pickett D, Irimura T, Anders EM, Reading PC. Macrophage receptors for infuenza A virus: role of the macrophage galactose-type lectin and mannose receptor in viral entry. J. Virol. 84(8), 3730-3737 (2010).
    • (2010) J. Virol. , vol.84 , Issue.8 , pp. 3730-3737
    • Upham, J.P.1    Pickett, D.2    Irimura, T.3    Anders, E.M.4    Reading, P.C.5
  • 90
    • 84892468991 scopus 로고    scopus 로고
    • The macrophage galactose-type lectin can function as an attachment and entry receptor for infuenza virus
    • Ng WC, Liong S, Tate MD et al. The macrophage galactose-type lectin can function as an attachment and entry receptor for infuenza virus. J. Virol. 88 (3), 1659-1672 (2014).
    • (2014) J. Virol. , vol.88 , Issue.3 , pp. 1659-1672
    • Ng, W.C.1    Liong, S.2    Tate, M.D.3
  • 91
    • 79960418204 scopus 로고    scopus 로고
    • Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with infuenza H5N1 and H1N1 viruses
    • Yu WC, Chan RW, Wang J et al. Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with infuenza H5N1 and H1N1 viruses. J. Virol. 85(14), 6844-6855 (2011).
    • (2011) J. Virol. , vol.85 , Issue.14 , pp. 6844-6855
    • Yu, W.C.1    Chan, R.W.2    Wang, J.3
  • 92
    • 78651505939 scopus 로고    scopus 로고
    • Correlation between sialic acid expression and infection of murine macrophages by different strains of infuenza virus
    • Tate MD, Brooks AG, Reading PC. Correlation between sialic acid expression and infection of murine macrophages by different strains of infuenza virus. Microbes Infect. 13(2), 202-207 (2011).
    • (2011) Microbes Infect. , vol.13 , Issue.2 , pp. 202-207
    • Tate, M.D.1    Brooks, A.G.2    Reading, P.C.3
  • 93
    • 79953248363 scopus 로고    scopus 로고
    • Responses of mouse airway epithelial cells and alveolar macrophages to virulent and avirulent strains of infuenza A virus
    • Tate MD, Schilter HC, Brooks AG, Reading PC. Responses of mouse airway epithelial cells and alveolar macrophages to virulent and avirulent strains of infuenza A virus. Viral Immunol. 24(2), 77-88 (2011).
    • (2011) Viral Immunol. , vol.24 , Issue.2 , pp. 77-88
    • Tate, M.D.1    Schilter, H.C.2    Brooks, A.G.3    Reading, P.C.4
  • 94
    • 77954492854 scopus 로고    scopus 로고
    • Critical role of airway macrophages in modulating disease severity during infuenza virus infection of mice
    • Tate MD, Pickett DL, Van Rooijen N, Brooks AG, Reading PC. Critical role of airway macrophages in modulating disease severity during infuenza virus infection of mice. J. Virol. 84(15), 7569-7580 (2010).
    • (2010) J. Virol. , vol.84 , Issue.15 , pp. 7569-7580
    • Tate, M.D.1    Pickett, D.L.2    Van Rooijen, N.3    Brooks, A.G.4    Reading, P.C.5
  • 95
    • 0030879806 scopus 로고    scopus 로고
    • Collectin-mediated antiviral host defense of the lung: Evidence from infuenza virus infection of mice
    • Reading PC, Morey LS, Crouch EC, Anders EM. Collectin-mediated antiviral host defense of the lung: evidence from infuenza virus infection of mice. J. Virol. 71(11), 8204-8212 (1997).
    • (1997) J. Virol. , vol.71 , Issue.11 , pp. 8204-8212
    • Reading, P.C.1    Morey, L.S.2    Crouch, E.C.3    Anders, E.M.4
  • 96
    • 77955656446 scopus 로고    scopus 로고
    • Infuenza viruses differ in ability to infect macrophages and to induce a local infammatory response following intraperitoneal injection of mice
    • Reading PC, Whitney PG, Pickett DL, Tate MD, Brooks AG. Infuenza viruses differ in ability to infect macrophages and to induce a local infammatory response following intraperitoneal injection of mice. Immunol. Cell Biol. 88(6), 641-650 (2010).
    • (2010) Immunol. Cell Biol. , vol.88 , Issue.6 , pp. 641-650
    • Reading, P.C.1    Whitney, P.G.2    Pickett, D.L.3    Tate, M.D.4    Brooks, A.G.5
  • 97
    • 79959824589 scopus 로고    scopus 로고
    • Highly pathogenic avian infuenza virus H5N1 infects alveolar macrophages without virus production or excessive TNF-alpha induction
    • Van Riel D, Leijten LM, Van Der Eerden M et al. Highly pathogenic avian infuenza virus H5N1 infects alveolar macrophages without virus production or excessive TNF-alpha induction. PLoS Pathog. 7(6), e1002099 (2011).
    • (2011) PLoS Pathog. , vol.7 , Issue.6 , pp. e1002099
    • Van Riel, D.1    Leijten, L.M.2    Van Der Eerden, M.3
  • 98
    • 0020039590 scopus 로고
    • Role of macrophage activation and interferon in the resistance of alveolar macrophages from infected mice to infuenza virus
    • Rodgers BC, Mims CA. Role of macrophage activation and interferon in the resistance of alveolar macrophages from infected mice to infuenza virus. Infect. Immun. 36(3), 1154-1159 (1982).
    • (1982) Infect. Immun. , vol.36 , Issue.3 , pp. 1154-1159
    • Rodgers, B.C.1    Mims, C.A.2
  • 99
    • 84873036417 scopus 로고    scopus 로고
    • The hemagglutinin protein of highly pathogenic H5N1 infuenza viruses overcomes an early block in the replication cycle to promote productive replication in macrophages
    • Cline TD, Karlsson EA, Seufzer BJ, Schultz-Cherry S. The hemagglutinin protein of highly pathogenic H5N1 infuenza viruses overcomes an early block in the replication cycle to promote productive replication in macrophages. J. Virol. 87(3), 1411-1419 (2013).
    • (2013) J. Virol. , vol.87 , Issue.3 , pp. 1411-1419
    • Cline, T.D.1    Karlsson, E.A.2    Seufzer, B.J.3    Schultz-Cherry, S.4
  • 100
    • 50849097044 scopus 로고    scopus 로고
    • H5N1 and 1918 pandemic infuenza virus infection results in early and excessive infltration of macrophages and neutrophils in the lungs of mice
    • Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM. H5N1 and 1918 pandemic infuenza virus infection results in early and excessive infltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog. 4(8), e1000115 (2008).
    • (2008) PLoS Pathog. , vol.4 , Issue.8 , pp. e1000115
    • Perrone, L.A.1    Plowden, J.K.2    Garcia-Sastre, A.3    Katz, J.M.4    Tumpey, T.M.5
  • 101
    • 84869025948 scopus 로고    scopus 로고
    • Infuenza A viruses target type II pneumocytes in the human lung
    • Weinheime r VK, Becher A, Tonnies M et al. Infuenza A viruses target type II pneumocytes in the human lung. J. Infect. Dis. 206(11), 1685-1694 (2012).
    • (2012) J. Infect. Dis. , vol.206 , Issue.11 , pp. 1685-1694
    • Weinheimer, V.K.1    Becher, A.2    Tonnies, M.3
  • 102
    • 84882928835 scopus 로고    scopus 로고
    • The severe pathogenicity of alveolar macrophage-depleted ferrets infected with 2009 pandemic H1N1 infuenza virus
    • Kim HM, Kang YM, Ku KB et al. The severe pathogenicity of alveolar macrophage-depleted ferrets infected with 2009 pandemic H1N1 infuenza virus. Virology 444(1-2), 394-403 (2013).
    • (2013) Virology , vol.444 , Issue.1-2 , pp. 394-403
    • Kim, H.M.1    Kang, Y.M.2    Ku, K.B.3
  • 103
    • 42449095509 scopus 로고    scopus 로고
    • Alveolar macrophages are indispensable for controlling infuenza viruses in lungs of pigs
    • Kim HM, Lee YW, Lee KJ et al. Alveolar macrophages are indispensable for controlling infuenza viruses in lungs of pigs. J. Virol. 82(9), 4265-4274 (2008).
    • (2008) J. Virol. , vol.82 , Issue.9 , pp. 4265-4274
    • Kim, H.M.1    Lee, Y.W.2    Lee, K.J.3
  • 104
    • 24644503497 scopus 로고    scopus 로고
    • Avian infuenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals
    • Maines TR, Lu XH, Erb SM et al. Avian infuenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals. J. Virol. 79(18), 11788-11800 (2005).
    • (2005) J. Virol. , vol.79 , Issue.18 , pp. 11788-11800
    • Maines, T.R.1    Lu, X.H.2    Erb, S.M.3
  • 105
    • 84890378712 scopus 로고    scopus 로고
    • Histopathological evaluation of the diversity of cells susceptible to H5N1 virulent avian infuenza virus
    • Ogiwara H, Yasui F, Munekata K et al. Histopathological evaluation of the diversity of cells susceptible to H5N1 virulent avian infuenza virus. Am. J. Pathol. 184(1), 171-183 (2014).
    • (2014) Am. J. Pathol. , vol.184 , Issue.1 , pp. 171-183
    • Ogiwara, H.1    Yasui, F.2    Munekata, K.3
  • 107
    • 84855388904 scopus 로고    scopus 로고
    • Infuenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation
    • Hoeve MA, Nash AA, Jackson D, Randall RE, Dransfeld I. Infuenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation. PLoS ONE 7(1), e29443 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.1 , pp. e29443
    • Hoeve, M.A.1    Nash, A.A.2    Jackson, D.3    Randall, R.E.4    Dransfeld, I.5
  • 108
    • 84867538000 scopus 로고    scopus 로고
    • The fate of infuenza A virus after infection of human macrophages and dendritic cells
    • Short KR, Brooks AG, Reading PC, Londrigan SL. The fate of infuenza A virus after infection of human macrophages and dendritic cells. J. Gen. Virol. 93(Pt 11), 2315-2325 (2012).
    • (2012) J. Gen. Virol. , vol.93 , pp. 2315-2325
    • Short, K.R.1    Brooks, A.G.2    Reading, P.C.3    Londrigan, S.L.4
  • 109
    • 0037038866 scopus 로고    scopus 로고
    • Induction of proinfammatory cytokines in human macrophages by infuenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
    • Cheung CY, Poon LLM, Lau AS et al. Induction of proinfammatory cytokines in human macrophages by infuenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 360(9348), 1831-1837 (2002).
    • (2002) Lancet , vol.360 , Issue.9348 , pp. 1831-1837
    • Cheung, C.Y.1    Poon, L.L.M.2    Lau, A.S.3
  • 110
    • 33745216720 scopus 로고    scopus 로고
    • Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian infuenza viruses
    • Zhou J, Law HK, Cheung CY, Ng IH, Peiris JS, Lau YL. Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian infuenza viruses. J. Infect. Dis. 194(1), 61-70 (2006).
    • (2006) J. Infect. Dis. , vol.194 , Issue.1 , pp. 61-70
    • Zhou, J.1    Law, H.K.2    Cheung, C.Y.3    Ng, I.H.4    Peiris, J.S.5    Lau, Y.L.6
  • 111
    • 59649110031 scopus 로고    scopus 로고
    • Lung epithelial apoptosis in infuenza virus pneumonia: The role of macrophage-expressed TNF-related apoptosis-inducing ligand
    • Herold S, Steinmueller M, Von Wulffen W et al. Lung epithelial apoptosis in infuenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand. J. Exp. Med. 205(13), 3065-3077 (2008).
    • (2008) J. Exp. Med. , vol.205 , Issue.13 , pp. 3065-3077
    • Herold, S.1    Steinmueller, M.2    Von Wulffen, W.3
  • 112
    • 84884540110 scopus 로고    scopus 로고
    • Cytokine and chemokine profles in lung tissues from fatal cases of 2009 pandemic infuenza A (H1N1): Role of the host immune response in pathogenesis
    • Gao R, Bhatnagar J, Blau DM et al. Cytokine and chemokine profles in lung tissues from fatal cases of 2009 pandemic infuenza A (H1N1): role of the host immune response in pathogenesis. Am. J. Pathol. 183 (4), 1258-1268 (2013).
    • (2013) Am. J. Pathol. , vol.183 , Issue.4 , pp. 1258-1268
    • Gao, R.1    Bhatnagar, J.2    Blau, D.M.3
  • 113
    • 84861809475 scopus 로고    scopus 로고
    • Apoptosis induced by avian H5N1 virus in human monocyte-derived macrophages involves TRAIL-inducing caspase-10 activation
    • Ekchariyawat P, Thitithanyanont A, Sirisinha S, Utaisincharoen P. Apoptosis induced by avian H5N1 virus in human monocyte-derived macrophages involves TRAIL-inducing caspase-10 activation. Innate Immun. 18(3), 390-397 (2012).
    • (2012) Innate Immun. , vol.18 , Issue.3 , pp. 390-397
    • Ekchariyawat, P.1    Thitithanyanont, A.2    Sirisinha, S.3    Utaisincharoen, P.4
  • 114
    • 84883401322 scopus 로고    scopus 로고
    • Immune dysfunction and bacterial coinfections following infuenza
    • Metzger DW, Sun K. Immune dysfunction and bacterial coinfections following infuenza. J. Immunol. 191(5), 2047-2052 (2013).
    • (2013) J. Immunol. , vol.191 , Issue.5 , pp. 2047-2052
    • Metzger, D.W.1    Sun, K.2
  • 115
    • 0028111256 scopus 로고
    • Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
    • Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 174(1-2), 83-93 (1994).
    • (1994) J. Immunol. Methods , vol.174 , Issue.1-2 , pp. 83-93
    • Van Rooijen, N.1    Sanders, A.2
  • 116
    • 84871484827 scopus 로고    scopus 로고
    • The broad-spectrum antiviral functions of IFIT and IFITM proteins
    • Diamond MS, Farzan M. The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat. Rev. Immunol. 13(1), 46-57 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , Issue.1 , pp. 46-57
    • Diamond, M.S.1    Farzan, M.2
  • 117
    • 84901337841 scopus 로고    scopus 로고
    • IFITM3 restricts infuenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion
    • Desai TM, Marin M, Chin CR, Savidis G, Brass AL, Melikyan GB. IFITM3 restricts infuenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion. PLoS Pathog. 10 (4), e1004048 (2014).
    • (2014) PLoS Pathog. , vol.10 , Issue.4 , pp. e1004048
    • Desai, T.M.1    Marin, M.2    Chin, C.R.3    Savidis, G.4    Brass, A.L.5    Melikyan, G.B.6
  • 118
    • 84862777209 scopus 로고    scopus 로고
    • IFITM3 restricts the morbidity and mortality associated with infuenza
    • Everitt AR, Clare S, Pertel T et al. IFITM3 restricts the morbidity and mortality associated with infuenza. Nature 484(7395), 519-523 (2012).
    • (2012) Nature , vol.484 , Issue.7395 , pp. 519-523
    • Everitt, A.R.1    Clare, S.2    Pertel, T.3
  • 119
    • 51849103407 scopus 로고    scopus 로고
    • Predominant role of bacterial pneumonia as a cause of death in pandemic infuenza: Implications for pandemic infuenza preparedness
    • Morens DM, Taubenberger JK, Fauci AS. Predominant role of bacterial pneumonia as a cause of death in pandemic infuenza: implications for pandemic infuenza preparedness. J. Infect. Dis. 198(7), 962-970 (2008).
    • (2008) J. Infect. Dis. , vol.198 , Issue.7 , pp. 962-970
    • Morens, D.M.1    Taubenberger, J.K.2    Fauci, A.S.3
  • 120
    • 84876004877 scopus 로고    scopus 로고
    • Kinetics of coinfection with infuenza A virus and Streptococcus pneumoniae
    • Smith AM, Adler FR, Ribeiro RM et al. Kinetics of coinfection with infuenza A virus and Streptococcus pneumoniae. PLoS Pathog. 9(3), e1003238 (2013).
    • (2013) PLoS Pathog. , vol.9 , Issue.3 , pp. e1003238
    • Smith, A.M.1    Adler, F.R.2    Ribeiro, R.M.3
  • 121
    • 79959800238 scopus 로고    scopus 로고
    • Airway immune homeostasis and implications for infuenza-induced infammation
    • Snelgrove RJ, Godlee A, Hussell T. Airway immune homeostasis and implications for infuenza-induced infammation. Trends Immunol. 32(7), 328-334 (2011).
    • (2011) Trends Immunol. , vol.32 , Issue.7 , pp. 328-334
    • Snelgrove, R.J.1    Godlee, A.2    Hussell, T.3
  • 123
    • 80455158415 scopus 로고    scopus 로고
    • Lethal synergism of 2009 pandemic H1N1 infuenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses
    • Kash JC, Walters KA, Davis AS et al. Lethal synergism of 2009 pandemic H1N1 infuenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses. MBio 2(5), e00172-11 (2011).
    • (2011) MBio , vol.2 , Issue.5 , pp. e00172-e00211
    • Kash, J.C.1    Walters, K.A.2    Davis, A.S.3
  • 124
    • 11244335975 scopus 로고    scopus 로고
    • The novel parainfuenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae
    • Alymova I V, Portner A, Takimoto T, Boyd KL, Babu YS, McCullers JA. The novel parainfuenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae. Antimicrob. Agents. Chemother. 49(1), 398-405 (2005).
    • (2005) Antimicrob. Agents. Chemother. , vol.49 , Issue.1 , pp. 398-405
    • Alymova, I.V.1    Portner, A.2    Takimoto, T.3    Boyd, K.L.4    Babu, Y.S.5    McCullers, J.A.6
  • 125
    • 84896399845 scopus 로고    scopus 로고
    • The co-pathogenesis of infuenza viruses with bacteria in the lung
    • McCullers JA. The co-pathogenesis of infuenza viruses with bacteria in the lung. Nat. Rev. Microbiol. 12(4), 252-262 (2014).
    • (2014) Nat. Rev. Microbiol. , vol.12 , Issue.4 , pp. 252-262
    • McCullers, J.A.1
  • 126
    • 80555156691 scopus 로고    scopus 로고
    • MARCO regulates early infammatory responses against infuenza: A useful macrophage function with adverse outcome
    • Ghosh S, Gregory D, Smith A, Kobzik L. MARCO regulates early infammatory responses against infuenza: a useful macrophage function with adverse outcome. Am. J. Respir. Cell Mol. Biol. 45 (5), 1036-1044 (2011).
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.45 , Issue.5 , pp. 1036-1044
    • Ghosh, S.1    Gregory, D.2    Smith, A.3    Kobzik, L.4
  • 127
    • 39549121053 scopus 로고    scopus 로고
    • Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory infuenza infection
    • Didierlaurent A, Goulding J, Patel S et al. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory infuenza infection. J. Exp. Med. 205(2), 323-329 (2008).
    • (2008) J. Exp. Med. , vol.205 , Issue.2 , pp. 323-329
    • Didierlaurent, A.1    Goulding, J.2    Patel, S.3
  • 128
    • 80052413795 scopus 로고    scopus 로고
    • Lowering the threshold of lung innate immune cell activation alters susceptibility to secondary bacterial superinfection
    • Goulding J, Godlee A, Vekaria S, Hilty M, Snelgrove R, Hussell T. Lowering the threshold of lung innate immune cell activation alters susceptibility to secondary bacterial superinfection. J. Infect. Dis. 204(7), 1086-1094 (2011).
    • (2011) J. Infect. Dis. , vol.204 , Issue.7 , pp. 1086-1094
    • Goulding, J.1    Godlee, A.2    Vekaria, S.3    Hilty, M.4    Snelgrove, R.5    Hussell, T.6
  • 129
    • 68849124811 scopus 로고    scopus 로고
    • Type i IFNs mediate development of postinfuenza bacterial pneumonia in mice
    • Shahangian A, Chow EK, Tian X et al. Type I IFNs mediate development of postinfuenza bacterial pneumonia in mice. J. Clin. Invest. 119 (7), 1910-1920 (2009).
    • (2009) J. Clin. Invest. , vol.119 , Issue.7 , pp. 1910-1920
    • Shahangian, A.1    Chow, E.K.2    Tian, X.3
  • 130
    • 33845505972 scopus 로고    scopus 로고
    • Both infuenza-induced neutrophil dysfunction and neutrophil-independent mechanisms contribute to increased susceptibility to a secondary Streptococcus pneumoniae infection
    • Mcnamee LA, Harmsen AG. Both infuenza-induced neutrophil dysfunction and neutrophil-independent mechanisms contribute to increased susceptibility to a secondary Streptococcus pneumoniae infection. Infect. Immun. 74(12), 6707-6721 (2006).
    • (2006) Infect. Immun. , vol.74 , Issue.12 , pp. 6707-6721
    • McNamee, L.A.1    Harmsen, A.G.2
  • 131
    • 84862651939 scopus 로고    scopus 로고
    • Innate imprinting of murine resident alveolar macrophages by allergic bronchial infammation causes a switch from hypo-infammatory to hyperinfammatory reactivity
    • Naessens T, Vander Beken S, Bogaert P et al. Innate imprinting of murine resident alveolar macrophages by allergic bronchial infammation causes a switch from hypo-infammatory to hyperinfammatory reactivity. Am. J. Pathol. 181(1), 174-184 (2012).
    • (2012) Am. J. Pathol. , vol.181 , Issue.1 , pp. 174-184
    • Naessens, T.1    Vander Beken, S.2    Bogaert, P.3
  • 132
    • 0034003375 scopus 로고    scopus 로고
    • The role of alpha/beta and gamma interferons in development of immunity to infuenza A virus in mice
    • Price GE, Gaszewska-Mastarlarz A, Moskophidis D. The role of alpha/beta and gamma interferons in development of immunity to infuenza A virus in mice. J. Virol. 74(9), 3996-4003 (2000).
    • (2000) J. Virol. , vol.74 , Issue.9 , pp. 3996-4003
    • Price, G.E.1    Gaszewska-Mastarlarz, A.2    Moskophidis, D.3
  • 133
    • 84881392472 scopus 로고    scopus 로고
    • Linezolid decreases susceptibility to secondary bacterial pneumonia postinfuenza infection in mice through its effects on IFN-gamma
    • Breslow-Deckman JM, Mattingly CM, Birket SE et al. Linezolid decreases susceptibility to secondary bacterial pneumonia postinfuenza infection in mice through its effects on IFN-gamma. J. Immunol. 191(4), 1792-1799 (2013).
    • (2013) J. Immunol. , vol.191 , Issue.4 , pp. 1792-1799
    • Breslow-Deckman, J.M.1    Mattingly, C.M.2    Birket, S.E.3
  • 134
    • 2942625718 scopus 로고    scopus 로고
    • IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after infuenza infection
    • Van Der Sluijs KF, Van Elden LJ, Nijhuis M et al. IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after infuenza infection. J. Immunol. 172(12), 7603-7609 (2004).
    • (2004) J. Immunol. , vol.172 , Issue.12 , pp. 7603-7609
    • Van Der Sluijs, K.F.1    Van Elden, L.J.2    Nijhuis, M.3
  • 135
    • 30944440041 scopus 로고    scopus 로고
    • Infuenza-induced expression of indoleamine 2, 3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia
    • Van Der Sluijs KF, Nijhuis M, Levels JH et al. Infuenza-induced expression of indoleamine 2, 3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia. J. Infect. Dis. 193(2), 214-222 (2006).
    • (2006) J. Infect. Dis. , vol.193 , Issue.2 , pp. 214-222
    • Van Der Sluijs, K.F.1    Nijhuis, M.2    Levels, J.H.3
  • 136
    • 77951490811 scopus 로고    scopus 로고
    • A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary infuenza A virus infection
    • Sun K, Torres L, Metzger DW. A detrimental effect of interleukin-10 on protective pulmonary humoral immunity during primary infuenza A virus infection. J. Virol. 84(10), 5007-5014 (2010).
    • (2010) J. Virol. , vol.84 , Issue.10 , pp. 5007-5014
    • Sun, K.1    Torres, L.2    Metzger, D.W.3
  • 137
    • 67649226607 scopus 로고    scopus 로고
    • IL-10 defciency unleashes an infuenza-specifc Th17 response and enhances survival against high-dose challenge
    • McKinstry KK, Strutt TM, Buck A et al. IL-10 defciency unleashes an infuenza-specifc Th17 response and enhances survival against high-dose challenge. J. Immunol. 182(12), 7353-7363 (2009).
    • (2009) J. Immunol. , vol.182 , Issue.12 , pp. 7353-7363
    • McKinstry, K.K.1    Strutt, T.M.2    Buck, A.3
  • 138
    • 84855968386 scopus 로고    scopus 로고
    • Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from infuenza
    • Chen WH, Toapanta FR, Shirey KA et al. Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from infuenza. Immunol. Lett. 141(2), 227-234 (2012).
    • (2012) Immunol. Lett. , vol.141 , Issue.2 , pp. 227-234
    • Chen, W.H.1    Toapanta, F.R.2    Shirey, K.A.3
  • 140
    • 84873368104 scopus 로고    scopus 로고
    • Bacterial superinfection following lung infammatory disorders
    • Habibzay M, Weiss G, Hussell T. Bacterial superinfection following lung infammatory disorders. Future Microbiol. 8(2), 247-256 (2013).
    • (2013) Future Microbiol. , vol.8 , Issue.2 , pp. 247-256
    • Habibzay, M.1    Weiss, G.2    Hussell, T.3
  • 141
    • 84859424158 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease
    • Decramer M, Janssens W, Miravitlles M. Chronic obstructive pulmonary disease. Lancet 379(9823), 1341-1351 (2012).
    • (2012) Lancet , vol.379 , Issue.9823 , pp. 1341-1351
    • Decramer, M.1    Janssens, W.2    Miravitlles, M.3
  • 142
    • 0034613727 scopus 로고    scopus 로고
    • Infuenza virus lung infection protects from respiratory syncytial virus-induced immunopathology
    • Walzl G, Tafuro S, Moss P, Openshaw PJ, Hussell T. Infuenza virus lung infection protects from respiratory syncytial virus-induced immunopathology. J. Exp. Med. 192(9), 1317-1326 (2000).
    • (2000) J. Exp. Med. , vol.192 , Issue.9 , pp. 1317-1326
    • Walzl, G.1    Tafuro, S.2    Moss, P.3    Openshaw, P.J.4    Hussell, T.5
  • 143
    • 34249005003 scopus 로고    scopus 로고
    • Herpesvirus latency confers symbiotic protection from bacterial infection
    • Barton ES, White DW, Cathelyn JS et al. Herpesvirus latency confers symbiotic protection from bacterial infection. Nature 447(7142), 326-329 (2007).
    • (2007) Nature , vol.447 , Issue.7142 , pp. 326-329
    • Barton, E.S.1    White, D.W.2    Cathelyn, J.S.3
  • 144
    • 84888205044 scopus 로고    scopus 로고
    • MHV68 latency modulates the host immune response to infuenza A virus
    • Saito F, Ito T, Connett JM et al. MHV68 latency modulates the host immune response to infuenza A virus. Infammation 36(6), 1295-1303 (2013).
    • (2013) Infammation , vol.36 , Issue.6 , pp. 1295-1303
    • Saito, F.1    Ito, T.2    Connett, J.M.3
  • 145
    • 49149089641 scopus 로고    scopus 로고
    • Human immunodefciency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells
    • Nicol MQ, Mathys JM, Pereira A, Ollington K, Ieong MH, Skolnik PR. Human immunodefciency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells. J. Virol. 82(16), 7790-7798 (2008).
    • (2008) J. Virol. , vol.82 , Issue.16 , pp. 7790-7798
    • Nicol, M.Q.1    Mathys, J.M.2    Pereira, A.3    Ollington, K.4    Ieong, M.H.5    Skolnik, P.R.6
  • 146
    • 77951746580 scopus 로고    scopus 로고
    • MyD88-dependent TLR4 signaling is selectively impaired in alveolar macrophages from asymptomatic HIV+ persons
    • Tachado SD, Li X, Bole M et al. MyD88-dependent TLR4 signaling is selectively impaired in alveolar macrophages from asymptomatic HIV+ persons. Blood 115 (17), 3606-3615 (2010).
    • (2010) Blood , vol.115 , Issue.17 , pp. 3606-3615
    • Tachado, S.D.1    Li, X.2    Bole, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.