Differential Host Response, Rather Than Early Viral Replication Efficiency, Correlates with Pathogenicity Caused by Influenza Viruses

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Askovich, Peter S ^a   Sanders, Catherine J ^b   Rosenberger, Carrie M ^a,c   Diercks, Alan H ^a   Dash, Pradyot ^b   Navarro, Garnet ^a   Vogel, Peter ^b   Doherty, Peter C ^a,b   Thomas, Paul G ^b   Aderem, Alan ^a  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 17; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE EXPRESSION PROFILING; GENETIC IDENTIFICATION; GROWTH INHIBITION; GROWTH RATE; HOST RESISTANCE; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; LD 50; LIFE CYCLE STAGE; LUNG INFECTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; TRACHEA DISEASE; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSCRIPTION; VIRUS VIRULENCE;

ANIMALS; BIOLOGICAL MARKERS; CELLS, CULTURED; FEMALE; GENE EXPRESSION PROFILING; HOST-PATHOGEN INTERACTIONS; LUNG; MICE; MICE, INBRED C57BL; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRACHEA; VIRUS REPLICATION;

EID: 84884470169     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074863     Document Type: Article

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