Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza

Immunology Letters

Volumn 141, Issue 2, 2012, Pages 227-234

  Chen, Wilbur H ^a   Toapanta, Franklin R ^a   Shirey, Kari Ann ^b   Zhang, Lei ^a   Giannelou, Angeliki ^a   Page, Carly ^b   Frieman, Matthew B ^b   Vogel, Stefanie N ^b   Cross, Alan S ^a  

^a University of Maryland School of Medicine Center for Vaccine Development   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Alternative activation; Alveolar macrophage; Influenza; Secondary pneumonia

Indexed keywords

ARGINASE 1; INTERLEUKIN 13; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SODIUM CHLORIDE; TOLL LIKE RECEPTOR;

ALTERNATIVELY ACTIVATED MACROPHAGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARGINASE 1 GENE; ARTICLE; BACTERIAL GENE; BACTERIAL PNEUMONIA; CONTROLLED STUDY; CYTOKINE RESPONSE; FEMALE; FIZZ1 GENE; GENE EXPRESSION; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOREGULATION; INFECTION SENSITIVITY; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; YM1 GENE;

ANIMALS; ARGINASE; BETA-N-ACETYLHEXOSAMINIDASES; CELLS, CULTURED; COMPLEMENT PATHWAY, ALTERNATIVE; DISEASE SUSCEPTIBILITY; GENE EXPRESSION REGULATION; INFLUENZA A VIRUS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-13; INTERLEUKIN-4; LECTINS; MACROPHAGE ACTIVATION; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; ORTHOMYXOVIRIDAE INFECTIONS; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE;

EID: 84855968386     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2011.10.009     Document Type: Article

References (36)

1. Morens D.M., Taubenberger J.K., Fauci A.S. Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis 2008, 198:962-970.
2. Louria D.B., Blumenfeld H.L., Ellis J.T., Kilbourne E.D., Rogers D.E. Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza. J Clin Invest 1959, 38:213-265.
3. Hers J.F., Masurel N., Mulder J. Bacteriology and histopathology of the respiratory tract and lungs in fatal Asian influenza. Lancet 1958, 2:1141-1143.
4. Lindsay M.I., Herrmann E.C., Morrow G.W., Brown A.L.Jr Hong Kong influenza: clinical, microbiologic, and pathologic features in 127 cases. JAMA 1970, 214:1825-1832.
5. Kashiwagi S., Ikematsu H., Hayashi J., Nomura H., Kajiyama W., Kaji M. An outbreak of influenza A (H3 N2) in a hospital for the elderly with emphasis on pulmonary complications. Jpn J Med 1988, 27:177-182.
6. Oliveira E.C., Marik P.E., Colice G. Influenza pneumonia: a descriptive study. Chest 2001, 119:1717-1723.
7. Ballinger M.N., Standiford T.J. Postinfluenza bacterial pneumonia: host defenses gone awry. J Interferon Cytokine Res 2010, 30:643-652.
8. van der Sluijs K.F., van der P.T., Lutter R., Juffermans N.P., Schultz M.J. Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications. Crit Care 2010, 14:219.
9. Didierlaurent A., Goulding J., Patel S., Snelgrove R., Low L., Bebien M., et al. Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection. J Exp Med 2008, 205:323-329.
10. Nickerson C.L., Jakab G.J. Pulmonary antibacterial defenses during mild and severe influenza virus infection. Infect Immun 1990, 58:2809-2814.
11. Weeks J.N., Boyd K.L., Rajam G., Ades E.W., McCullers J.A. Immunotherapy with a combination of intravenous immune globulin and p4 Peptide rescues mice from postinfluenza pneumococcal pneumonia. Antimicrob Agents Chemother 2011, 55:2276-2281.
12. Sun K., Metzger D.W. Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection. Nat Med 2008, 14:558-564.
13. van der Sluijs K.F., van Elden L.J., Nijhuis M., Schuurman R., Pater J.M., Florquin S., et al. IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection. J Immunol 2004, 172:7603-7609.
14. Mosser D.M., Edwards J.P. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008, 8:958-969.
15. Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003, 3:23-35.
16. Chen W.H., Basu S., Bhattacharjee A.K., Cross A.S. Enhanced antibody responses to a detoxified lipopolysaccharide-group B meningococcal outer membrane protein vaccine are due to synergistic engagement of Toll-like receptors. Innate Immun 2010, 16:322-332.
17. Toapanta F.R., Ross T.M. Impaired immune responses in the lungs of aged mice following influenza infection. Respir Res 2009, 10:112.
18. Shirey K.A., Cole L.E., Keegan A.D., Vogel S.N. Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. J Immunol 2008, 181:4159-4167.
19. Karlstrom A., Boyd K.L., English B.K., McCullers J.A. Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza. J Infect Dis 2009, 199:311-319.
20. LeVine A.M., Koeningsknecht V., Stark J.M. Decreased pulmonary clearance of S pneumoniae following influenza A infection in mice. J Virol Methods 2001, 94:173-186.
21. McCullers J.A., Rehg J.E. Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor. J Infect Dis 2002, 186:341-350.
22. Lambrecht B.N. Alveolar macrophage in the driver's seat. Immunity 2006, 24:366-368.
23. Snelgrove R.J., Godlee A., Hussell T. Airwaymmune homeostasis and implications for influenza-induced inflammation. Trends Immunol 2011, 32:328-334.
24. Gordon S., Martinez F.O. Alternative activation of macrophages: mechanism and functions. Immunity 2010, 32:593-604.
25. Smith M.W., Schmidt J.E., Rehg J.E., Orihuela C.J., McCullers J.A. Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza. Comp Med 2007, 57:82-89.
26. Raes G., Brys L., Dahal B.K., Brandt J., Grooten J., Brombacher F., et al. Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol 2005, 77:321-327.
27. McAuley J.L., Hornung F., Boyd K.L., Smith A.M., McKeon R., Bennink J., et al. Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host Microbe 2007, 2:240-249.
28. McCullers J.A., Bartmess K.C. Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae. J Infect Dis 2003, 187:1000-1009.
29. Peltola V.T., Murti K.G., McCullers J.A. Influenza virus neuraminidase contributes to secondary bacterial pneumonia. J Infect Dis 2005, 192:249-257.
30. King Q.O., Lei B., Harmsen A.G. Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection. J Infect Dis 2009, 200:537-545.
31. McCullers J.A. Insights into the interaction between influenza virus and pneumococcus. Clin Microbiol Rev 2006, 19:571-582.
32. Stein M., Keshav S., Harris N., Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med 1992, 176:287-292.
33. Loke P., Nair M.G., Parkinson J., Guiliano D., Blaxter M., Allen J.E. IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunol 2002, 3:7.
34. Medeiros A.I., Serezani C.H., Lee S.P., Peters-Golden M. Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling. J Exp Med 2009, 206:61-68.
35. Varin A., Mukhopadhyay S., Herbein G., Gordon S. Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion. Blood 2010, 115:353-362.
36. Snelgrove R.J., Goulding J., Didierlaurent A.M., Lyonga D., Vekaria S., Edwards L., et al. A critical function for CD200 in lung immune homeostasis and the severity of influenza infection. Nat Immunol 2008, 9:1074-1083.