Patterns of somatic alterations between matched primary and metastatic colorectal tumors characterized by whole-genome sequencing

Genomics

Volumn 104, Issue 4, 2014, Pages 234-241

  Xie, Tao ^a   Cho, Yong Beom ^b   Wang, Kai ^a   Huang, Donghui ^a   Hong, Hye Kyung ^b   Choi, Yoon La ^b   Ko, Young Hyeh ^b   Nam, Do Hyun ^b   Jin, Juyoun ^b   Yang, Heekyoung ^b   Fernandez, Julio ^a   Deng, Shibing ^a   Rejto, Paul A ^a   Lee, Woo Yong ^b   Mao, Mao ^a  

^a PFIZER INC   (United States)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Colorectal cancer; Metastasis; Somatic alteration; Whole genome sequencing

Indexed keywords

NUCLEOTIDE; CADHERIN; CELL CYCLE PROTEIN; DCLK1 PROTEIN, HUMAN; F BOX PROTEIN; FAT2 PROTEIN, HUMAN; FBXW7 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE;

ADULT; AGED; ARTICLE; CANCER CELL; CANCER GROWTH; CLONAL EVOLUTION; COLON CARCINOGENESIS; CONTROLLED STUDY; COPY NUMBER VARIATION; DCLK1 GENE; DISTANT METASTASIS; FAT2 GENE; FBXW7 GENE; FEMALE; GENE; GENE DELETION; GENE DOSAGE; GENE INSERTION; GENE MUTATION; GENE SEQUENCE; GENETIC DISORDER; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN GENOME; HUMAN TISSUE; MALE; METASTATIC COLORECTAL CANCER; MOLECULAR PATHOLOGY; MUTATIONAL ANALYSIS; PREDICTION; PRIMARY TUMOR; COLORECTAL TUMOR; GENETICS; GERMLINE MUTATION; INDEL MUTATION; LIVER TUMOR; MIDDLE AGED; PATHOLOGY; SECONDARY;

AGED; CADHERINS; CELL CYCLE PROTEINS; COLORECTAL NEOPLASMS; DNA COPY NUMBER VARIATIONS; F-BOX PROTEINS; FEMALE; GENOME, HUMAN; GERM-LINE MUTATION; HUMANS; INDEL MUTATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROTEIN-SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES;

EID: 84908231465     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2014.07.012     Document Type: Article

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