CDC4/FBXW7 and the 'just enough' model of tumourigenesis

Journal of Pathology

Volumn 227, Issue 2, 2012, Pages 131-135

  Davis, Hayley ^a   Tomlinson, Ian ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

continuum model; FBXW7 CDC4; just enough model; just right model; two hits

Indexed keywords

PEPTIDES AND PROTEINS; PROTEIN FBXW7; UNCLASSIFIED DRUG;

ALLELE; CARCINOGENESIS; CDC4 GENE; FBXW7 GENE; GENE; GENE MUTATION; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW;

CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; F-BOX PROTEINS; GENETIC PREDISPOSITION TO DISEASE; HAPLOINSUFFICIENCY; HETEROZYGOTE; HUMANS; MODELS, GENETIC; MUTATION; NEOPLASMS; UBIQUITIN-PROTEIN LIGASES;

EID: 84860667547     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4004     Document Type: Review

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