-
1
-
-
28244432240
-
The blood-brain barrier transmigrating single domain antibody: Mechanisms of transport and antigenic epitopes in human brain endothelial cells
-
Abulrob, A., Sprong, H., Van Bergen en Henegouwen, P., and Stanimirovic, D. (2005). The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells. J. Neurochem. 95, 1201-1214. doi: 10.1111/j.1471-4159.2005.03463.x
-
(2005)
J. Neurochem.
, vol.95
, pp. 1201-1214
-
-
Abulrob, A.1
Sprong, H.2
Van Bergen en Henegouwen, P.3
Stanimirovic, D.4
-
2
-
-
57649186797
-
Post-ischemic brain damage: Pathophysiology and role of inflammatory mediators
-
Amantea, D., Nappi, G., Bernardi, G., Bagetta, G., and Corasaniti, M. T. (2009). Post-ischemic brain damage: pathophysiology and role of inflammatory mediators. FEBS J. 276, 13-26. doi: 10.1111/j.1742-4658.2008.06766.x
-
(2009)
FEBS J.
, vol.276
, pp. 13-26
-
-
Amantea, D.1
Nappi, G.2
Bernardi, G.3
Bagetta, G.4
Corasaniti, M.T.5
-
3
-
-
0030767656
-
Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
-
Arbabi Ghahroudi, M., Desmyter, A., Wyns, L., Hamers, R., and Muyldermans, S. (1997). Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett. 414, 521-526. doi: 10.1016/s0014-5793(97)01062-4
-
(1997)
FEBS Lett.
, vol.414
, pp. 521-526
-
-
Arbabi Ghahroudi, M.1
Desmyter, A.2
Wyns, L.3
Hamers, R.4
Muyldermans, S.5
-
4
-
-
84856585760
-
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia
-
Arbeloa, J., Pérez-Samartín, A., Gottlieb, M., and Matute, C. (2012). P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia. Neurobiol. Dis. 45, 954-961. doi: 10.1016/j.nbd.2011.12.014
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 954-961
-
-
Arbeloa, J.1
Pérez-Samartín, A.2
Gottlieb, M.3
Matute, C.4
-
5
-
-
84908232996
-
The P2X7 receptor channel: Recent developments and the use of P2X7 antagonists in models of disease
-
Bartlett, R., Stokes, L., and Sluyter, R. (2014). The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease. Pharmacol. Rev. 66, 638-675. doi: 10.1124/pr.113.008003
-
(2014)
Pharmacol. Rev.
, vol.66
, pp. 638-675
-
-
Bartlett, R.1
Stokes, L.2
Sluyter, R.3
-
6
-
-
67650685580
-
Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspecific cross-reacting antigen
-
Behar, G., Chames, P., Teulon, I., Cornillon, A., Alshoukr, F., Roquet, F., et al. (2009). Llama single-domain antibodies directed against nonconventional epitopes of tumor-associated carcinoembryonic antigen absent from nonspecific cross-reacting antigen. FEBS J. 276, 3881-3893. doi: 10.1111/j.1742-4658.2009.07101.x
-
(2009)
FEBS J.
, vol.276
, pp. 3881-3893
-
-
Behar, G.1
Chames, P.2
Teulon, I.3
Cornillon, A.4
Alshoukr, F.5
Roquet, F.6
-
7
-
-
38349164198
-
Isolation and characterization of anti-FcgammaRIII (CD16) llama single-domain antibodies that activate natural killer cells
-
Behar, G., Sibéril, S., Groulet, A., Chames, P., Pugnière, M., Boix, C., et al. (2008). Isolation and characterization of anti-FcgammaRIII (CD16) llama single-domain antibodies that activate natural killer cells. Protein Eng. Des. Sel. 21, 1-10. doi: 10.1093/protein/gzm064
-
(2008)
Protein Eng. Des. Sel.
, vol.21
, pp. 1-10
-
-
Behar, G.1
Sibéril, S.2
Groulet, A.3
Chames, P.4
Pugnière, M.5
Boix, C.6
-
8
-
-
70549113042
-
A one-step exclusion-binding procedure for the purification of functional heavy-chain and mammalian-type γ globulins from camelid sera
-
Blanc, M. R., Anouassi, A., Abed, M. A., Tsikis, G., Canepa, S., Labas, V., et al. (2009). A one-step exclusion-binding procedure for the purification of functional heavy-chain and mammalian-type γ globulins from camelid sera. Biotechnol. Appl. Biochem. 54, 207-212. doi: 10.1042/ba20090208
-
(2009)
Biotechnol. Appl. Biochem.
, vol.54
, pp. 207-212
-
-
Blanc, M.R.1
Anouassi, A.2
Abed, M.A.3
Tsikis, G.4
Canepa, S.5
Labas, V.6
-
9
-
-
84883355779
-
Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function
-
Blanchetot, C., Verzijl, D., Mujić-Delić, A., Bosch, L., Rem, L., Leurs, R., et al. (2013). Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function. J. Biol. Chem. 288, 25173-25182. doi: 10.1074/jbc.m113.467969
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 25173-25182
-
-
Blanchetot, C.1
Verzijl, D.2
Mujić-Delić, A.3
Bosch, L.4
Rem, L.5
Leurs, R.6
-
10
-
-
84866457004
-
Glycemic control and chronic dosing of rhesus monkeys with a fusion protein of iduronidase and a monoclonal antibody against the human insulin receptor
-
Boado, R. J., Hui, E. K.-W., Lu, J. Z., and Pardridge, W. M. (2012). Glycemic control and chronic dosing of rhesus monkeys with a fusion protein of iduronidase and a monoclonal antibody against the human insulin receptor. Drug Metab. Dispos. 40, 2021-2025. doi: 10.1124/dmd.112.046375
-
(2012)
Drug Metab. Dispos.
, vol.40
, pp. 2021-2025
-
-
Boado, R.J.1
Hui, E.K.-W.2
Lu, J.Z.3
Pardridge, W.M.4
-
11
-
-
79955935367
-
CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia
-
Choe, C.-U., Lardong, K., Gelderblom, M., Ludewig, P., Leypoldt, F., Koch-Nolte, F., et al. (2011). CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia. PLoS One 6:e19046. doi: 10.1371/journal.pone.0019046
-
(2011)
PLoS One
, vol.6
-
-
Choe, C.-U.1
Lardong, K.2
Gelderblom, M.3
Ludewig, P.4
Leypoldt, F.5
Koch-Nolte, F.6
-
12
-
-
84939874282
-
ATP signaling in brain: Release, excitotoxicity and potential therapeutic targets
-
[Epub ahead of print]
-
Cisneros-Mejorado, A., Pérez-Samartín, A., Gottlieb, M., and Matute, C. (2014). ATP signaling in brain: release, excitotoxicity and potential therapeutic targets. Cell. Mol. Neurobiol. doi: 10.1007/s10571-014-0092-3. [Epub ahead of print].
-
(2014)
Cell. Mol. Neurobiol.
-
-
Cisneros-Mejorado, A.1
Pérez-Samartín, A.2
Gottlieb, M.3
Matute, C.4
-
13
-
-
0025835310
-
Making antibody fragments using phage display libraries
-
Clackson, T., Hoogenboom, H. R., Griffiths, A. D., and Winter, G. (1991). Making antibody fragments using phage display libraries. Nature 352, 624-628. doi: 10.1038/352624a0
-
(1991)
Nature
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
14
-
-
84884672721
-
Efflux of monoclonal antibodies from rat brain by neonatal Fc receptor, FcRn
-
Cooper, P. R., Ciambrone, G. J., Kliwinski, C. M., Maze, E., Johnson, L., Li, Q., et al. (2013). Efflux of monoclonal antibodies from rat brain by neonatal Fc receptor, FcRn. Brain Res. 1534, 13-21. doi: 10.1016/j.brainres.2013.08.035
-
(2013)
Brain Res.
, vol.1534
, pp. 13-21
-
-
Cooper, P.R.1
Ciambrone, G.J.2
Kliwinski, C.M.3
Maze, E.4
Johnson, L.5
Li, Q.6
-
15
-
-
33745032737
-
Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis
-
Coppieters, K., Dreier, T., Silence, K., de Haard, H., Lauwereys, M., Casteels, P., et al. (2006). Formatted anti-tumor necrosis factor alpha VHH proteins derived from camelids show superior potency and targeting to inflamed joints in a murine model of collagen-induced arthritis. Arthritis Rheum. 54, 1856-1866. doi: 10.1002/art.21827
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 1856-1866
-
-
Coppieters, K.1
Dreier, T.2
Silence, K.3
de Haard, H.4
Lauwereys, M.5
Casteels, P.6
-
16
-
-
33645241975
-
Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies
-
De Genst, E., Silence, K., Decanniere, K., Conrath, K., Loris, R., Kinne, J., et al. (2006). Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc. Natl. Acad. Sci. U S A 103, 4586-4591. doi: 10.1073/pnas.0505379103
-
(2006)
Proc. Natl. Acad. Sci. u S A
, vol.103
, pp. 4586-4591
-
-
De Genst, E.1
Silence, K.2
Decanniere, K.3
Conrath, K.4
Loris, R.5
Kinne, J.6
-
17
-
-
0036182644
-
Single-domain antibody fragments with high conformational stability
-
Dumoulin, M., Conrath, K., Van Meirhaeghe, A., Meersman, F., Heremans, K., Frenken, L. G. J., et al. (2002). Single-domain antibody fragments with high conformational stability. Protein Sci. 11, 500-515. doi: 10.1110/ps.34602
-
(2002)
Protein Sci.
, vol.11
, pp. 500-515
-
-
Dumoulin, M.1
Conrath, K.2
Van Meirhaeghe, A.3
Meersman, F.4
Heremans, K.5
Frenken, L.G.J.6
-
18
-
-
84908002106
-
A novel platform for engineering blood-brain barrier-crossing bispecific biologics
-
[Epub ahead of print]
-
Farrington, G. K., Caram-Salas, N., Haqqani, A. S., Brunette, E., Eldredge, J., Pepinsky, B., et al. (2014). A novel platform for engineering blood-brain barrier-crossing bispecific biologics. FASEB J. doi: 10.1096/fj.14-253369. [Epub ahead of print].
-
(2014)
FASEB J.
-
-
Farrington, G.K.1
Caram-Salas, N.2
Haqqani, A.S.3
Brunette, E.4
Eldredge, J.5
Pepinsky, B.6
-
20
-
-
84908231344
-
High efficiency cell-specific targeting of cytokine activity
-
Garcin, G., Paul, F., Staufenbiel, M., Bordat, Y., Van der Heyden, J., Wilmes, S., et al. (2014). High efficiency cell-specific targeting of cytokine activity. Nat. Commun. 5:3016. doi: 10.1038/ncomms4016
-
(2014)
Nat. Commun.
, vol.5
, pp. 3016
-
-
Garcin, G.1
Paul, F.2
Staufenbiel, M.3
Bordat, Y.4
Van der Heyden, J.5
Wilmes, S.6
-
21
-
-
0027310612
-
Naturally occurring antibodies devoid of light chains
-
Hamers-Casterman, C., Atarhouch, T., Muyldermans, S., Robinson, G., Hamers, C., Songa, E. B., et al. (1993). Naturally occurring antibodies devoid of light chains. Nature 363, 446-448. doi: 10.1038/363446a0
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamers-Casterman, C.1
Atarhouch, T.2
Muyldermans, S.3
Robinson, G.4
Hamers, C.5
Songa, E.B.6
-
22
-
-
84878714164
-
Nanobodies and their potential applications
-
Hassanzadeh-Ghassabeh, G., Devoogdt, N., De Pauw, P., Vincke, C., and Muyldermans, S. (2013). Nanobodies and their potential applications. Nanomedicine (Lond) 8, 1013-1026. doi: 10.2217/nnm.13.86
-
(2013)
Nanomedicine (Lond)
, vol.8
, pp. 1013-1026
-
-
Hassanzadeh-Ghassabeh, G.1
Devoogdt, N.2
De Pauw, P.3
Vincke, C.4
Muyldermans, S.5
-
23
-
-
84872074957
-
CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice
-
Huang, J., Li, Y., Tang, Y., Tang, G., Yang, G.-Y., and Wang, Y. (2013). CXCR4 antagonist AMD3100 protects blood-brain barrier integrity and reduces inflammatory response after focal ischemia in mice. Stroke 44, 190-197. doi: 10.1161/strokeaha.112.670299
-
(2013)
Stroke
, vol.44
, pp. 190-197
-
-
Huang, J.1
Li, Y.2
Tang, Y.3
Tang, G.4
Yang, G.-Y.5
Wang, Y.6
-
24
-
-
78649420520
-
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway
-
Hubert, S., Rissiek, B., Klages, K., Huehn, J., Sparwasser, T., Haag, F., et al. (2010). Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. J. Exp. Med. 207, 2561-2568. doi: 10.1084/jem.20091154
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2561-2568
-
-
Hubert, S.1
Rissiek, B.2
Klages, K.3
Huehn, J.4
Sparwasser, T.5
Haag, F.6
-
25
-
-
79960141471
-
The immunology of stroke: From mechanisms to translation
-
Iadecola, C., and Anrather, J. (2011). The immunology of stroke: from mechanisms to translation. Nat. Med. 17, 796-808. doi: 10.1038/nm.2399
-
(2011)
Nat. Med.
, vol.17
, pp. 796-808
-
-
Iadecola, C.1
Anrather, J.2
-
26
-
-
78650573881
-
CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
-
Jähnichen, S., Blanchetot, C., Maussang, D., Gonzalez-Pajuelo, M., Chow, K. Y., Bosch, L., et al. (2010). CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells. Proc. Natl. Acad. Sci. U S A 107, 20565-20570. doi: 10.1073/pnas.1012865107
-
(2010)
Proc. Natl. Acad. Sci. u S A
, vol.107
, pp. 20565-20570
-
-
Jähnichen, S.1
Blanchetot, C.2
Maussang, D.3
Gonzalez-Pajuelo, M.4
Chow, K.Y.5
Bosch, L.6
-
27
-
-
35948991091
-
Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo
-
Koch-Nolte, F., Reyelt, J., Schössow, B., Schwarz, N., Scheuplein, F., Rothenburg, S., et al. (2007). Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo. FASEB J. 21, 3490-3498. doi: 10.1096/fj.07-8661com
-
(2007)
FASEB J.
, vol.21
, pp. 3490-3498
-
-
Koch-Nolte, F.1
Reyelt, J.2
Schössow, B.3
Schwarz, N.4
Scheuplein, F.5
Rothenburg, S.6
-
28
-
-
1842589283
-
Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice
-
Komine-Kobayashi, M., Chou, N., Mochizuki, H., Nakao, A., Mizuno, Y., and Urabe, T. (2004). Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice. Stroke 35, 958-963. doi: 10.1161/01.str.0000120321.30916.8e
-
(2004)
Stroke
, vol.35
, pp. 958-963
-
-
Komine-Kobayashi, M.1
Chou, N.2
Mochizuki, H.3
Nakao, A.4
Mizuno, Y.5
Urabe, T.6
-
29
-
-
77956326466
-
Averting inflammation by targeting the cytokine environment
-
Kopf, M., Bachmann, M. F., and Marsland, B. J. (2010). Averting inflammation by targeting the cytokine environment. Nat. Rev. Drug Discov. 9, 703-718. doi: 10.1038/nrd2805
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 703-718
-
-
Kopf, M.1
Bachmann, M.F.2
Marsland, B.J.3
-
30
-
-
84895426492
-
-
Patent
-
Laeremans, T., Stortelers, C., Koch-Nolte, F., Gonzalez, M., Assuncao, J., and van Rompaey, P. (2010). Genetic immunization for producing immunoglobulins against cell-associated antigens such as p2x7, cxcr7 or cxcr4. Patent
-
(2010)
Genetic Immunization for Producing Immunoglobulins Against Cell-associated Antigens Such as P2x7, Cxcr7 or Cxcr4.
-
-
Laeremans, T.1
Stortelers, C.2
Koch-Nolte, F.3
Gonzalez, M.4
Assuncao, J.5
van Rompaey, P.6
-
31
-
-
84868107927
-
Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: Application to brain imaging
-
Li, T., Bourgeois, J. P., Celli, S., Glacial, F., Le Sourd, A. M., Mecheri, S., et al. (2012). Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging. FASEB J. 26, 3969-3979. doi: 10.1096/fj.11-201384
-
(2012)
FASEB J.
, vol.26
, pp. 3969-3979
-
-
Li, T.1
Bourgeois, J.P.2
Celli, S.3
Glacial, F.4
Le Sourd, A.M.5
Mecheri, S.6
-
32
-
-
84860756103
-
Immune mechanisms of stroke
-
Magnus, T., Wiendl, H., and Kleinschnitz, C. (2012). Immune mechanisms of stroke. Curr. Opin. Neurol. 25, 334-340. doi: 10.1097/WCO.0b013e328352ede6
-
(2012)
Curr. Opin. Neurol.
, vol.25
, pp. 334-340
-
-
Magnus, T.1
Wiendl, H.2
Kleinschnitz, C.3
-
33
-
-
84885594077
-
Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo
-
Maussang, D., Mujić-Delić, A., Descamps, F. J., Stortelers, C., Vanlandschoot, P., Stigter-van Walsum, M., et al. (2013). Llama-derived single variable domains (nanobodies) directed against chemokine receptor CXCR7 reduce head and neck cancer cell growth in vivo. J. Biol. Chem. 288, 29562-29572. doi: 10.1074/jbc.m113.498436
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 29562-29572
-
-
Maussang, D.1
Mujić-Delić, A.2
Descamps, F.J.3
Stortelers, C.4
Vanlandschoot, P.5
Stigter-Van Walsum, M.6
-
34
-
-
84880324634
-
The art of blocking ADP-ribosyltransferases (ARTs): Nanobodies as experimental and therapeutic tools to block mammalian and toxin ARTs
-
Menzel, S., Rissiek, B., Haag, F., Goldbaum, F. A., and Koch-Nolte, F. (2013). The art of blocking ADP-ribosyltransferases (ARTs): nanobodies as experimental and therapeutic tools to block mammalian and toxin ARTs.FEBS J. 280, 3543-3550. doi: 10.1111/febs.12313
-
(2013)
FEBS J.
, vol.280
, pp. 3543-3550
-
-
Menzel, S.1
Rissiek, B.2
Haag, F.3
Goldbaum, F.A.4
Koch-Nolte, F.5
-
35
-
-
58149352350
-
The HMGB1 receptor RAGE mediates ischemic brain damage
-
Muhammad, S., Barakat, W., Stoyanov, S., Murikinati, S., Yang, H., Tracey, K. J., et al. (2008). The HMGB1 receptor RAGE mediates ischemic brain damage. J. Neurosci. 28, 12023-12031. doi: 10.1523/JNEUROSCI.2435-08.2008
-
(2008)
J. Neurosci.
, vol.28
, pp. 12023-12031
-
-
Muhammad, S.1
Barakat, W.2
Stoyanov, S.3
Murikinati, S.4
Yang, H.5
Tracey, K.J.6
-
36
-
-
0036480118
-
Selection of phage-displayed llama single-domain antibodies that transmigrate across human blood-brain barrier endothelium
-
Muruganandam, A., Tanha, J., Narang, S., and Stanimirovic, D. (2002). Selection of phage-displayed llama single-domain antibodies that transmigrate across human blood-brain barrier endothelium. FASEB J. 16, 240-242. doi: 10.1096/fj.01-0343fje
-
(2002)
FASEB J.
, vol.16
, pp. 240-242
-
-
Muruganandam, A.1
Tanha, J.2
Narang, S.3
Stanimirovic, D.4
-
37
-
-
84878935042
-
Nanobodies: Natural single-domain antibodies
-
Muyldermans, S. (2013). Nanobodies: natural single-domain antibodies. Annu. Rev. Biochem. 82, 775-797. doi: 10.1146/annurev-biochem-063011-092449
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 775-797
-
-
Muyldermans, S.1
-
38
-
-
35548955496
-
Fc-receptors as regulators of immunity
-
Nimmerjahn, F., and Ravetch, J. V. (2007). Fc-receptors as regulators of immunity. Adv. Immunol. 96, 179-204. doi: 10.1016/s0065-2776(07)96005-8
-
(2007)
Adv. Immunol.
, vol.96
, pp. 179-204
-
-
Nimmerjahn, F.1
Ravetch, J.V.2
-
39
-
-
84868573143
-
Drug transport across the blood-brain barrier
-
Pardridge, W. M. (2012). Drug transport across the blood-brain barrier. J. Cereb. Blood Flow Metab. 32, 1959-1972. doi: 10.1038/jcbfm.2012.126
-
(2012)
J. Cereb. Blood Flow Metab.
, vol.32
, pp. 1959-1972
-
-
Pardridge, W.M.1
-
40
-
-
84899474157
-
Technical Advance: A new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells
-
Rissiek, B., Danquah, W., Haag, F., and Koch-Nolte, F. (2014a). Technical Advance: a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells. J. Leukoc. Biol. 95, 543-549. doi: 10.1189/jlb.0713407
-
(2014)
J. Leukoc. Biol.
, vol.95
, pp. 543-549
-
-
Rissiek, B.1
Danquah, W.2
Haag, F.3
Koch-Nolte, F.4
-
41
-
-
84908223770
-
ADP-Ribosylation of P2X7: A matter of life and death for regulatory T cells and natural killer T cells
-
[Epub ahead of print]
-
Rissiek, B., Haag, F., Boyer, O., Koch-Nolte, F., and Adriouch, S. (2014b). ADP-Ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells. Curr. Top. Microbiol. Immunol. doi: 10.1007/82_2014_420. [Epub ahead of print].
-
(2014)
Curr. Top. Microbiol. Immunol.
-
-
Rissiek, B.1
Haag, F.2
Boyer, O.3
Koch-Nolte, F.4
Adriouch, S.5
-
42
-
-
84882241230
-
Single-domain antibody-based and linker-free bispecific antibodies targeting Fc γ RIII induce potent antitumor activity without recruiting regulatory T cells
-
Rozan, C., Cornillon, A., Pétiard, C., Chartier, M., Behar, G., Boix, C., et al. (2013). Single-domain antibody-based and linker-free bispecific antibodies targeting Fc γ RIII induce potent antitumor activity without recruiting regulatory T cells. Mol. Cancer Ther. 12, 1481-1491. doi: 10.1158/1535-7163.mct-12-1012
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 1481-1491
-
-
Rozan, C.1
Cornillon, A.2
Pétiard, C.3
Chartier, M.4
Behar, G.5
Boix, C.6
-
43
-
-
84881121382
-
Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke
-
Ruscher, K., Kuric, E., Liu, Y., Walter, H. L., Issazadeh-Navikas, S., Englund, E., et al. (2013). Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke. J. Cereb. Blood Flow Metab. 33, 1225-1234. doi: 10.1038/jcbfm.2013.71
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 1225-1234
-
-
Ruscher, K.1
Kuric, E.2
Liu, Y.3
Walter, H.L.4
Issazadeh-Navikas, S.5
Englund, E.6
-
44
-
-
75349113325
-
A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes
-
Scheuplein, F., Rissiek, B., Driver, J. P., Chen, Y.-G., Koch-Nolte, F., and Serreze, D. V. (2010). A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes. J. Autoimmun. 34, 145-154. doi: 10.1016/j.jaut.2009.08.012
-
(2010)
J. Autoimmun.
, vol.34
, pp. 145-154
-
-
Scheuplein, F.1
Rissiek, B.2
Driver, J.P.3
Chen, Y.-G.4
Koch-Nolte, F.5
Serreze, D.V.6
-
45
-
-
0142188258
-
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
-
Seman, M., Adriouch, S., Scheuplein, F., Krebs, C., Freese, D., Glowacki, G., et al. (2003). NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor. Immunity 19, 571-582. doi: 10.1016/S1074-7613(03)00266-8
-
(2003)
Immunity
, vol.19
, pp. 571-582
-
-
Seman, M.1
Adriouch, S.2
Scheuplein, F.3
Krebs, C.4
Freese, D.5
Glowacki, G.6
-
46
-
-
84878129969
-
Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice
-
Sousa, L. F. D. C., Coelho, F. M., Rodrigues, D. H., Campos, A. C., Barcelos, L. D. S., Teixeira, M. M., et al. (2013). Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice. Clinics (Sao Paulo) 68, 391-394. doi: 10.6061/clinics/2013(03)oa17
-
(2013)
Clinics (Sao Paulo)
, vol.68
, pp. 391-394
-
-
Sousa, L.F.D.C.1
Coelho, F.M.2
Rodrigues, D.H.3
Campos, A.C.4
Barcelos, L.D.S.5
Teixeira, M.M.6
-
47
-
-
0036420965
-
Molecular recognition in antibody-antigen complexes
-
Sundberg, E. J., and Mariuzza, R. A. (2002). Molecular recognition in antibody-antigen complexes. Adv. Protein Chem. 61, 119-160. doi: 10.1016/s0065-3233(02)61004-6
-
(2002)
Adv. Protein Chem.
, vol.61
, pp. 119-160
-
-
Sundberg, E.J.1
Mariuzza, R.A.2
-
48
-
-
53349171633
-
Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: Taking advantage of modular Nanobody technology
-
Tijink, B. M., Laeremans, T., Budde, M., Stigter-van Walsum, M., Dreier, T., de Haard, H. J., et al. (2008). Improved tumor targeting of anti-epidermal growth factor receptor Nanobodies through albumin binding: taking advantage of modular Nanobody technology. Mol. Cancer Ther. 7, 2288-2297. doi: 10.1158/1535-7163.mct-07-2384
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2288-2297
-
-
Tijink, B.M.1
Laeremans, T.2
Budde, M.3
Stigter-Van Walsum, M.4
Dreier, T.5
de Haard, H.J.6
-
49
-
-
80053309997
-
Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model
-
Tsai, L.-K., Wang, Z., Munasinghe, J., Leng, Y., Leeds, P., and Chuang, D.-M. (2011). Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model. Stroke 42, 2932-2939. doi: 10.1161/strokeaha.110.612788
-
(2011)
Stroke
, vol.42
, pp. 2932-2939
-
-
Tsai, L.-K.1
Wang, Z.2
Munasinghe, J.3
Leng, Y.4
Leeds, P.5
Chuang, D.-M.6
-
50
-
-
70449429345
-
The development of nanobodies for therapeutic applications
-
Van Bockstaele, F., Holz, J. B., and Revets, H. (2009). The development of nanobodies for therapeutic applications. Curr. Opin. Investig. Drugs 10, 1212-1224.
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, pp. 1212-1224
-
-
Van Bockstaele, F.1
Holz, J.B.2
Revets, H.3
-
51
-
-
77249133143
-
Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis
-
Vandenbroucke, K., de Haard, H., Beirnaert, E., Dreier, T., Lauwereys, M., Huyck, L., et al. (2010). Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis. Mucosal Immunol. 3, 49-56. doi: 10.1038/mi.2009.116
-
(2010)
Mucosal Immunol.
, vol.3
, pp. 49-56
-
-
Vandenbroucke, K.1
de Haard, H.2
Beirnaert, E.3
Dreier, T.4
Lauwereys, M.5
Huyck, L.6
-
52
-
-
84874271571
-
Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier
-
Wang, D., El-Amouri, S. S., Dai, M., Kuan, C.-Y., Hui, D. Y., Brady, R. O., et al. (2013). Engineering a lysosomal enzyme with a derivative of receptor-binding domain of apoE enables delivery across the blood-brain barrier. Proc. Natl. Acad. Sci. U S A 110, 2999-3004. doi: 10.1073/pnas.1222742110
-
(2013)
Proc. Natl. Acad. Sci. u S A
, vol.110
, pp. 2999-3004
-
-
Wang, D.1
El-Amouri, S.S.2
Dai, M.3
Kuan, C.-Y.4
Hui, D.Y.5
Brady, R.O.6
-
53
-
-
68349117269
-
Single domain antibodies: Promising experimental and therapeutic tools in infection and immunity
-
Wesolowski, J., Alzogaray, V., Reyelt, J., Unger, M., Juarez, K., Urrutia, M., et al. (2009). Single domain antibodies: promising experimental and therapeutic tools in infection and immunity. Med. Microbiol. Immunol. 198, 157-174. doi: 10.1007/s00430-009-0116-7
-
(2009)
Med. Microbiol. Immunol.
, vol.198
, pp. 157-174
-
-
Wesolowski, J.1
Alzogaray, V.2
Reyelt, J.3
Unger, M.4
Juarez, K.5
Urrutia, M.6
-
54
-
-
84892716254
-
Small nanobody drugs win big backing from pharma
-
Williams, S. C. P. (2013). Small nanobody drugs win big backing from pharma. Nat. Med. 19, 1355-1356. doi: 10.1038/nm1113-1355
-
(2013)
Nat. Med.
, vol.19
, pp. 1355-1356
-
-
Williams, S.C.P.1
-
55
-
-
84880161805
-
Receptor-mediated endocytosis and brain delivery of therapeutic biologics
-
Xiao, G., and Gan, L.-S. (2013). Receptor-mediated endocytosis and brain delivery of therapeutic biologics. Int. J. Cell Biol. 2013:703545. doi: 10.1155/2013/703545
-
(2013)
Int. J. Cell Biol.
, vol.2013
, pp. 703545
-
-
Xiao, G.1
Gan, L.-S.2
|