Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations

Epigenetics

Volumn 9, Issue 9, 2014, Pages 1228-1237

  Glossop, John R ^a,b   Emes, Richard D ^c,d   Nixon, Nicola B ^b   Haworth, Kim E ^a   Packham, Jon C ^b   Dawes, Peter T ^b   Fryer, Anthony A ^a   Mattey, Derek L ^a,b   Farrell, William E ^a  

^a KEELE UNIVERSITY   (United Kingdom)

^b HAYWOOD HOSPITAL   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

B lymphocyte; CpG; DNA methylation; Genome wide; Illumina 450K array; Rheumatoid arthritis; T lymphocyte

Indexed keywords

CYTOSINE;

ADULT; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE ASSOCIATION; DNA METHYLATION; FEMALE; FLOW CYTOMETRY; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PYROSEQUENCING; RHEUMATOID ARTHRITIS; SEQUENCE ANALYSIS; T LYMPHOCYTE; AGED; BLOOD; GENETICS; HUMAN GENOME; LONG INTERSPERSED REPEAT; METABOLISM; MIDDLE AGED;

AGED; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; CPG ISLANDS; DNA METHYLATION; FEMALE; GENOME, HUMAN; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MIDDLE AGED; T-LYMPHOCYTES;

EID: 84908155154     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.29718     Document Type: Article

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