Hypomethylation of proximal CpG motif of interleukin-10 promoter regulates its expression in human rheumatoid arthritis

Acta Pharmacologica Sinica

Volumn 32, Issue 11, 2011, Pages 1373-1380

  Fu, Li Hong ^a   Ma, Chun Ling ^a   Cong, Bin ^a   Li, Shu Jin ^a   Chen, Hai Ying ^a   Zhang, Jing Ge ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

bioinformatics; CpG motif; cyclicAMP response element binding protein; DNA methylation; interleukin 10; interspecies conserved sequence; promoter regions; rheumatoid arthritis

Indexed keywords

AZACITIDINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; INTERLEUKIN 10; MESSENGER RNA;

ADULT; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOREGULATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PYROSEQUENCING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS;

ADOLESCENT; ADULT; ANIMALS; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CPG ISLANDS; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-10; MALE; MICE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; YOUNG ADULT;

EID: 80755130457     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.98     Document Type: Article

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