Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

EMBO Molecular Medicine

Volumn 6, Issue 10, 2014, Pages 1246-1262

  Pascual Lucas, Maria ^a   Viana da Silva, Silvia ^b   Di Scala, Marianna ^a   Garcia Barroso, Carolina ^a   González Aseguinolaza, Gloria ^a   Mulle, Christophe ^b   Alberini, Cristina M ^c   Cuadrado Tejedor, Mar ^a,d   Garcia Osta, Ana ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c NEW YORK UNIVERSITY   (United States)

^d UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Alzheimer's disease; IGF1; IGF2; IGF2R; Synaptic plasticity

Indexed keywords

AMYLOID; PARVOVIRUS VECTOR; SOMATOMEDIN B; SOMATOMEDIN C; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN LEVEL; CONTROLLED STUDY; DENDRITIC SPINE; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE THERAPY; GENE TRANSFER; HIPPOCAMPUS; MALE; MEMORY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPSE; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; VIRAL GENE DELIVERY SYSTEM; AGED; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CONFOCAL MICROSCOPY; DEPENDOPARVOVIRUS; DISEASE MODEL; GENE VECTOR; GENETICS; HEK293 CELL LINE; HUMAN; MEMORY DISORDER; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; TUMOR CELL LINE; WESTERN BLOTTING;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; DENDRITIC SPINES; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC VECTORS; HEK293 CELLS; HIPPOCAMPUS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; MALE; MEMORY DISORDERS; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYNAPTIC TRANSMISSION;

EID: 84908135739     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201404228     Document Type: Article

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