Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folates

Journal of Biological Chemistry

Volumn 289, Issue 42, 2014, Pages 29386-29396

  Lawrence, Scott A ^a   Titus, Steven A ^b   Ferguson, Jennifer ^b   Heineman, Amy L ^b   Taylor, Shirley M ^a,b   Moran, Richard G ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; MAMMALS;

CYTOSOLIC; CYTOSOLS; FOLATES; ISOFORMS; MITOCHONDRIAL MEMBRANES; SUB-CELLULAR; SYNTHETASES;

MITOCHONDRIA;

COMPLEMENTARY DNA; CYTOSOLIC FOLYLPOLYGLUTAMATE SYNTHASE; DOXYCYCLINE; FOLIC ACID; FOLYLPOLYGLUTAMATE SYNTHASE; GLYCINE; LIPOFECTAMINE; MITOCHONDRIAL FOLYLPOLYGLUTAMATE SYNTHASE; PTEROPTIN; PURINE; THYMIDINE; UNCLASSIFIED DRUG; ISOPROTEIN; PEPTIDE SYNTHASE;

ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL GROWTH; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CELL SURVIVAL; CHO CELL LINE; CONTROLLED STUDY; CYTOSOL; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME LOCALIZATION; FPGS GENE; GENE EXPRESSION; GENETIC TRANSFECTION; HAMSTER; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROMOTER REGION; TRANSCRIPTION INITIATION SITE; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; CRICETULUS; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; SEQUENCE HOMOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSOL; DNA, COMPLEMENTARY; FOLIC ACID; HUMANS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE SYNTHASES; PROTEIN ISOFORMS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84908108336     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.593244     Document Type: Article

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