Modular construction of a functional artificial epothilone polyketide pathway

ACS Synthetic Biology

Volumn 3, Issue 10, 2014, Pages 759-772

  Oßwald, Corina ^a   Zipf, Gregor ^b   Schmidt, Gisela ^b   Maier, Josef ^c   Bernauer, Hubert S ^b   Müller, Rolf ^a   Wenzel, Silke C ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b ATG Biosynthetics GmbH   (Germany)

^c Information Services to Life Science   (Germany)

Author keywords

Artificial gene cluster; Epothilone; Heterologous expression; Pathway engineering; Polyketide biosynthesis; Synthetic biology

Indexed keywords

POLYKETIDE; CODON; EPOTHILONE DERIVATIVE; POLYKETIDE SYNTHASE; SYNTHETIC DNA;

ARTICLE; BIOSYNTHESIS; GENE CLUSTER; HETEROLOGOUS EXPRESSION; MYXOCOCCUS XANTHUS; NONHUMAN; NUCLEOTIDE SEQUENCE; RESTRICTION SITE; SORANGIUM CELLULOSUM; ALGORITHM; BIOTECHNOLOGY; CHEMISTRY; CODON; GENETIC ENGINEERING; GENETICS; METABOLISM; MULTIGENE FAMILY; MYXOCOCCALES; SYNTHETIC BIOLOGY;

ALGORITHMS; BIOSYNTHETIC PATHWAYS; BIOTECHNOLOGY; CODON; EPOTHILONES; GENES, SYNTHETIC; GENETIC ENGINEERING; MULTIGENE FAMILY; MYXOCOCCALES; MYXOCOCCUS XANTHUS; POLYKETIDE SYNTHASES; POLYKETIDES; SYNTHETIC BIOLOGY;

EID: 84908067985     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb300080t     Document Type: Article

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