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Volumn 9, Issue 10, 2014, Pages

Loss of Optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OPTINEURIN; EYE PROTEIN; OPTN PROTEIN, HUMAN; OPTN PROTEIN, MOUSE; TRANSCRIPTION FACTOR IIIA;

EID: 84908045074     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109922     Document Type: Article
Times cited : (22)

References (117)
  • 1
    • 18244385269 scopus 로고    scopus 로고
    • Adult-onset primary open-angle glaucoma caused by mutations in optineurin
    • Rezaie T, Child A, Hitchings R, Brice G, Miller L, et al. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science 295: 1077-1079. doi:10.1126/science.1066901.
    • (2002) Science , vol.295 , pp. 1077-1079
    • Rezaie, T.1    Child, A.2    Hitchings, R.3    Brice, G.4    Miller, L.5
  • 3
    • 69249214220 scopus 로고    scopus 로고
    • A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family
    • Xiao Z, Meng Q, Tsai JC, Yuan H, Xu N, et al. (2009) A novel optineurin genetic mutation associated with open-angle glaucoma in a Chinese family. Mol Vis 15: 1649-1654.
    • (2009) Mol Vis , vol.15 , pp. 1649-1654
    • Xiao, Z.1    Meng, Q.2    Tsai, J.C.3    Yuan, H.4    Xu, N.5
  • 4
    • 33847105099 scopus 로고    scopus 로고
    • Variation in optineurin (OPTN) allele frequencies between and within populations
    • Ayala-Lugo RM, Pawar H, Reed DM, Lichter PR, Moroi SE, et al. (2007) Variation in optineurin (OPTN) allele frequencies between and within populations. Mol Vis 13: 151-163.
    • (2007) Mol Vis , vol.13 , pp. 151-163
    • Ayala-Lugo, R.M.1    Pawar, H.2    Reed, D.M.3    Lichter, P.R.4    Moroi, S.E.5
  • 5
    • 34248161997 scopus 로고    scopus 로고
    • SNPs and interaction analyses of noelin 2, myocilin, and optineurin genes in Japanese patients with open-angle glaucoma
    • Funayama T, Mashima Y, Ohtake Y, Ishikawa K, Fuse N, et al. (2006) SNPs and interaction analyses of noelin 2, myocilin, and optineurin genes in Japanese patients with open-angle glaucoma. Invest Ophthalmol Vis Sci 47: 5368-5375. doi:10.1167/iovs.06-0196.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 5368-5375
    • Funayama, T.1    Mashima, Y.2    Ohtake, Y.3    Ishikawa, K.4    Fuse, N.5
  • 6
    • 33748921413 scopus 로고    scopus 로고
    • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States
    • Hauser MA, Sena DF, Flor J, Walter J, Auguste J, et al. (2006) Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. J Glaucoma 15: 358-363. doi:10.1097/01.ijg.0000212255.17950.42.
    • (2006) J Glaucoma , vol.15 , pp. 358-363
    • Hauser, M.A.1    Sena, D.F.2    Flor, J.3    Walter, J.4    Auguste, J.5
  • 7
    • 33749368752 scopus 로고    scopus 로고
    • Low penetrance of His26Asp mutation in the optineurin gene in a Japanese family with normal-tension glaucoma
    • Yasuda N, Nakamoto K, Funayama T, Mashima Y (2006) [Low penetrance of His26Asp mutation in the optineurin gene in a Japanese family with normal-tension glaucoma]. Nippon Ganka Gakkai Zasshi 110: 594-600.
    • (2006) Nippon Ganka Gakkai Zasshi , vol.110 , pp. 594-600
    • Yasuda, N.1    Nakamoto, K.2    Funayama, T.3    Mashima, Y.4
  • 9
    • 33646125608 scopus 로고    scopus 로고
    • Polymorphisms of myocilin and optineurin in primary open angle glaucoma patients
    • Yao H, Cheng C, Fan B, Tam O, Tham C, et al. (2006) [Polymorphisms of myocilin and optineurin in primary open angle glaucoma patients]. Zhonghua Yi Xue Za Zhi 86: 554-559.
    • (2006) Zhonghua Yi Xue Za Zhi , vol.86 , pp. 554-559
    • Yao, H.1    Cheng, C.2    Fan, B.3    Tam, O.4    Tham, C.5
  • 10
    • 33644830016 scopus 로고    scopus 로고
    • Mutations and polymorphisms in the genes for myocilin and optineur in as the risk factors of primary open-angle glaucoma
    • Rakhmanov VV, Nikitina NI, Zakharova FM, Astakhov IS, Kvasova MD, et al. (2005) [Mutations and polymorphisms in the genes for myocilin and optineur in as the risk factors of primary open-angle glaucoma]. Genetika 41: 1567-1574.
    • (2005) Genetika , vol.41 , pp. 1567-1574
    • Rakhmanov, V.V.1    Nikitina, N.I.2    Zakharova, F.M.3    Astakhov, I.S.4    Kvasova, M.D.5
  • 11
    • 26244440242 scopus 로고    scopus 로고
    • Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma
    • Mukhopadhyay A, Komatireddy S, Acharya M, Bhattacharjee A, Mandal AK, et al. (2005) Evaluation of Optineurin as a candidate gene in Indian patients with primary open angle glaucoma. Mol Vis 11: 792-797.
    • (2005) Mol Vis , vol.11 , pp. 792-797
    • Mukhopadhyay, A.1    Komatireddy, S.2    Acharya, M.3    Bhattacharjee, A.4    Mandal, A.K.5
  • 12
    • 26244460821 scopus 로고    scopus 로고
    • SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients
    • Fan BJ, Wang DY, Fan DSP, Tam POS, Lam DSC, et al. (2005) SNPs and interaction analyses of myocilin, optineurin, and apolipoprotein E in primary open angle glaucoma patients. Mol Vis 11: 625-631.
    • (2005) Mol Vis , vol.11 , pp. 625-631
    • Fan, B.J.1    Wang, D.Y.2    Fan, D.S.P.3    Tam, P.O.S.4    Lam, D.S.C.5
  • 13
    • 25444484751 scopus 로고    scopus 로고
    • Prevalence of myocilin and optineurin sequence variants in German normal tension glaucoma patients
    • Weisschuh N, Neumann D, Wolf C, Wissinger B, Gramer E (2005) Prevalence of myocilin and optineurin sequence variants in German normal tension glaucoma patients. Mol Vis 11: 284-287.
    • (2005) Mol Vis , vol.11 , pp. 284-287
    • Weisschuh, N.1    Neumann, D.2    Wolf, C.3    Wissinger, B.4    Gramer, E.5
  • 14
    • 9444288213 scopus 로고    scopus 로고
    • Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma
    • Funayama T, Ishikawa K, Ohtake Y, Tanino T, Kurosaka D, et al. (2004) Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci 45: 4359-4367. doi:10.1167/iovs.03-1403.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 4359-4367
    • Funayama, T.1    Ishikawa, K.2    Ohtake, Y.3    Tanino, T.4    Kurosaka, D.5
  • 15
    • 8644259362 scopus 로고    scopus 로고
    • Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: The Blue Mountains Eye Study
    • Baird PN, Richardson AJ, Craig JE, Mackey DA, Rochtchina E, et al. (2004) Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study. Clin Experiment Ophthalmol 32: 518-522. doi:10.1111/j.1442-9071.2004.00886.x.
    • (2004) Clin Experiment Ophthalmol , vol.32 , pp. 518-522
    • Baird, P.N.1    Richardson, A.J.2    Craig, J.E.3    Mackey, D.A.4    Rochtchina, E.5
  • 17
    • 24644500827 scopus 로고    scopus 로고
    • Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene
    • Aung T, Rezaie T, Okada K, Viswanathan AC, Child AH, et al. (2005) Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene. Invest Ophthalmol Vis Sci 46: 2816-2822. doi:10.1167/iovs.04-1133.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 2816-2822
    • Aung, T.1    Rezaie, T.2    Okada, K.3    Viswanathan, A.C.4    Child, A.H.5
  • 18
    • 3242732130 scopus 로고    scopus 로고
    • Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population
    • Fuse N, Takahashi K, Akiyama H, Nakazawa T, Seimiya M, et al. (2004) Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population. J Glaucoma 13: 299-303.
    • (2004) J Glaucoma , vol.13 , pp. 299-303
    • Fuse, N.1    Takahashi, K.2    Akiyama, H.3    Nakazawa, T.4    Seimiya, M.5
  • 19
    • 0142248853 scopus 로고    scopus 로고
    • Prevalence of optineurin sequence variants in adult primary open angle glaucoma: Implications for diagnostic testing
    • Aung T, Ebenezer ND, Brice G, Child AH, Prescott Q, et al. (2003) Prevalence of optineurin sequence variants in adult primary open angle glaucoma: implications for diagnostic testing. J Med Genet 40: e101.
    • (2003) J Med Genet , vol.40 , pp. e101
    • Aung, T.1    Ebenezer, N.D.2    Brice, G.3    Child, A.H.4    Prescott, Q.5
  • 20
    • 84862523328 scopus 로고    scopus 로고
    • Screening glaucoma genes in adult glaucoma suggests a multiallelic contribution of CYP1B1 to open-angle glaucoma phenotypes
    • Patel HY, Richards AJ, De Karolyi B, Best SJ, Danesh-Meyer HV, et al. (2012) Screening glaucoma genes in adult glaucoma suggests a multiallelic contribution of CYP1B1 to open-angle glaucoma phenotypes. Clin Experiment Ophthalmol 40: e208-217. doi:10.1111/j.1442-9071.2011.02714.x.
    • (2012) Clin Experiment Ophthalmol , vol.40 , pp. e208-e217
    • Patel, H.Y.1    Richards, A.J.2    De Karolyi, B.3    Best, S.J.4    Danesh-Meyer, H.V.5
  • 21
    • 79952900157 scopus 로고    scopus 로고
    • Analysis of OPTN as a causative gene for amyotrophic lateral sclerosis
    • Belzil VV, Daoud H, Desjarlais A, Bouchard JP, Dupré N, et al. (2011) Analysis of OPTN as a causative gene for amyotrophic lateral sclerosis. Neurobiol Aging 32: 555.e13-14. doi:10.1016/j.neurobiolaging.2010.10.001.
    • (2011) Neurobiol Aging , vol.32 , pp. 555.e13-555.e14
    • Belzil, V.V.1    Daoud, H.2    Desjarlais, A.3    Bouchard, J.P.4    Dupré, N.5
  • 22
    • 79952898709 scopus 로고    scopus 로고
    • Screening of OPTN in French familial amyotrophic lateral sclerosis
    • Millecamps S, Boillée S, Chabrol E, Camu W, Cazeneuve C, et al. (2011) Screening of OPTN in French familial amyotrophic lateral sclerosis. Neurobiol Aging 32: 557.e11-13. doi:10.1016/j.neurobiolaging.2010.11.005.
    • (2011) Neurobiol Aging , vol.32 , pp. 557.e11-557.e13
    • Millecamps, S.1    Boillée, S.2    Chabrol, E.3    Camu, W.4    Cazeneuve, C.5
  • 23
    • 79960837950 scopus 로고    scopus 로고
    • Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation
    • Ito H, Nakamura M, Komure O, Ayaki T, Wate R, et al. (2011) Clinicopathologic study on an ALS family with a heterozygous E478G optineurin mutation. Acta Neuropathol (Berl) 122: 223-229. doi:10.1007/s00401-011-0842-y.
    • (2011) Acta Neuropathol (Berl) , vol.122 , pp. 223-229
    • Ito, H.1    Nakamura, M.2    Komure, O.3    Ayaki, T.4    Wate, R.5
  • 24
    • 80051570216 scopus 로고    scopus 로고
    • Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population
    • Sugihara K, Maruyama H, Kamada M, Morino H, Kawakami H (2011) Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population. Neurobiol Aging 32: 1923.e9-10. doi:10.1016/j.neurobiolaging.2011.03.024.
    • (2011) Neurobiol Aging , vol.32 , pp. 1923.e9-1923.e10
    • Sugihara, K.1    Maruyama, H.2    Kamada, M.3    Morino, H.4    Kawakami, H.5
  • 25
    • 80053629733 scopus 로고    scopus 로고
    • Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis
    • Del Bo R, Tiloca C, Pensato V, Corrado L, Ratti A, et al. (2011) Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 82: 1239-1243. doi:10.1136/jnnp.2011.242313.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 1239-1243
    • Del Bo, R.1    Tiloca, C.2    Pensato, V.3    Corrado, L.4    Ratti, A.5
  • 26
    • 81355147499 scopus 로고    scopus 로고
    • Novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS
    • Tümer Z, Bertelsen B, Gredal O, Magyari M, Nielsen KC, et al. (2012) Novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS. Neurobiol Aging 33: 208.e1-5. doi:10.1016/j.neurobiolaging.2011.07.001.
    • (2012) Neurobiol Aging , vol.33 , pp. 208.e1-208.e5
    • Tümer, Z.1    Bertelsen, B.2    Gredal, O.3    Magyari, M.4    Nielsen, K.C.5
  • 27
    • 84855582418 scopus 로고    scopus 로고
    • Optineurin mutations in Japanese amyotrophic lateral sclerosis
    • Iida A, Hosono N, Sano M, Kamei T, Oshima S, et al. (2012) Optineurin mutations in Japanese amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 83: 233-235. doi:10.1136/jnnp.2010.234963.
    • (2012) J Neurol Neurosurg Psychiatry , vol.83 , pp. 233-235
    • Iida, A.1    Hosono, N.2    Sano, M.3    Kamei, T.4    Oshima, S.5
  • 29
    • 84863602161 scopus 로고    scopus 로고
    • Contribution of major amyotrophic lateral sclerosis genes to the etiology of sporadic disease
    • Lattante S, Conte A, Zollino M, Luigetti M, Del Grande A, et al. (2012) Contribution of major amyotrophic lateral sclerosis genes to the etiology of sporadic disease. Neurology 79: 66-72. doi:10.1212/WNL.0b013e31825dceca.
    • (2012) Neurology , vol.79 , pp. 66-72
    • Lattante, S.1    Conte, A.2    Zollino, M.3    Luigetti, M.4    Del Grande, A.5
  • 30
    • 77952419246 scopus 로고    scopus 로고
    • Mutations of optineurin in amyotrophic lateral sclerosis
    • Maruyama H, Morino H, Ito H, Izumi Y, Kato H, et al. (2010) Mutations of optineurin in amyotrophic lateral sclerosis. Nature 465: 223-226. doi:10.1038/nature08971.
    • (2010) Nature , vol.465 , pp. 223-226
    • Maruyama, H.1    Morino, H.2    Ito, H.3    Izumi, Y.4    Kato, H.5
  • 32
    • 84873426054 scopus 로고    scopus 로고
    • A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany
    • Weishaupt JH, Waibel S, Birve A, Volk AE, Mayer B, et al. (2013) A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany. Neurobiol Aging 34: 1516.e9-15. doi:10.1016/j.neurobiolaging.2012.09.007.
    • (2013) Neurobiol Aging , vol.34 , pp. 1516.e9-1516.e15
    • Weishaupt, J.H.1    Waibel, S.2    Birve, A.3    Volk, A.E.4    Mayer, B.5
  • 33
    • 84871192467 scopus 로고    scopus 로고
    • Extensive genetics of ALS: A population-based study in Italy
    • Chiò A, Calvo A, Mazzini L, Cantello R, Mora G, et al. (2012) Extensive genetics of ALS: a population-based study in Italy. Neurology 79: 1983-1989. doi:10.1212/WNL.0b013e3182735d36.
    • (2012) Neurology , vol.79 , pp. 1983-1989
    • Chiò, A.1    Calvo, A.2    Mazzini, L.3    Cantello, R.4    Mora, G.5
  • 34
    • 84875470602 scopus 로고    scopus 로고
    • Progressive aphasia as the presenting symptom in a patient with amyotrophic lateral sclerosis with a novel mutation in the OPTN gene
    • Czell D, Andersen PM, Neuwirth C, Morita M, Weber M (2013) Progressive aphasia as the presenting symptom in a patient with amyotrophic lateral sclerosis with a novel mutation in the OPTN gene. Amyotroph Lateral Scler Front Degener 14: 138-140. doi:10.3109/21678421.2012.756525.
    • (2013) Amyotroph Lateral Scler Front Degener , vol.14 , pp. 138-140
    • Czell, D.1    Andersen, P.M.2    Neuwirth, C.3    Morita, M.4    Weber, M.5
  • 35
    • 83155185448 scopus 로고    scopus 로고
    • Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: A case series
    • Ueno H, Kobatake K, Matsumoto M, Morino H, Maruyama H, et al. (2011) Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: a case series. J Med Case Reports 5: 573. doi:10.1186/1752-1947-5-573.
    • (2011) J Med Case Reports , vol.5 , pp. 573
    • Ueno, H.1    Kobatake, K.2    Matsumoto, M.3    Morino, H.4    Maruyama, H.5
  • 36
    • 79959745220 scopus 로고    scopus 로고
    • Genome-wide association identifies three new susceptibility loci for Paget's disease of bone
    • Albagha OME, Wani SE, Visconti MR, Alonso N, Goodman K, et al. (2011) Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet 43: 685-689. doi:10.1038/ng.845.
    • (2011) Nat Genet , vol.43 , pp. 685-689
    • Albagha, O.M.E.1    Wani, S.E.2    Visconti, M.R.3    Alonso, N.4    Goodman, K.5
  • 37
    • 84865636771 scopus 로고    scopus 로고
    • Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone
    • Michou L, Conceic¸ão N, Morissette J, Gagnon E, Miltenberger-Miltenyi G, et al. (2012) Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone. Bone 51: 720-728. doi:10.1016/j.bone.2012.06.028.
    • (2012) Bone , vol.51 , pp. 720-728
    • Michou, L.1    Conceic¸ão, N.2    Morissette, J.3    Gagnon, E.4    Miltenberger-Miltenyi, G.5
  • 38
    • 78649320390 scopus 로고    scopus 로고
    • The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes
    • Chung PYJ, Beyens G, Boonen S, Papapoulos S, Geusens P, et al. (2010) The majority of the genetic risk for Paget's disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes. Hum Genet 128: 615-626. doi:10.1007/s00439-010-0888-2.
    • (2010) Hum Genet , vol.128 , pp. 615-626
    • Chung, P.Y.J.1    Beyens, G.2    Boonen, S.3    Papapoulos, S.4    Geusens, P.5
  • 40
    • 79954581188 scopus 로고    scopus 로고
    • Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease
    • Ito H, Fujita K, Nakamura M, Wate R, Kaneko S, et al. (2011) Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease. Acta Neuropathol (Berl) 121: 555-557. doi:10.1007/s00401-011-0809-z.
    • (2011) Acta Neuropathol (Berl) , vol.121 , pp. 555-557
    • Ito, H.1    Fujita, K.2    Nakamura, M.3    Wate, R.4    Kaneko, S.5
  • 41
    • 80855123814 scopus 로고    scopus 로고
    • Brainstem and spinal cord motor neuron involvement with optineurin inclusions in proximal-dominant hereditary motor and sensory neuropathy
    • Fujita K, Yoshida M, Sako W, Maeda K, Hashizume Y, et al. (2011) Brainstem and spinal cord motor neuron involvement with optineurin inclusions in proximal-dominant hereditary motor and sensory neuropathy. J Neurol Neurosurg Psychiatry 82: 1402-1403. doi:10.1136/jnnp-2011-300783.
    • (2011) J Neurol Neurosurg Psychiatry , vol.82 , pp. 1402-1403
    • Fujita, K.1    Yoshida, M.2    Sako, W.3    Maeda, K.4    Hashizume, Y.5
  • 42
    • 84855204007 scopus 로고    scopus 로고
    • Optineurin in Huntington's disease intranuclear inclusions
    • Schwab C, Yu S, McGeer EG, McGeer PL (2012) Optineurin in Huntington's disease intranuclear inclusions. Neurosci Lett 506: 149-154. doi:10.1016/j.neulet.2011.10.070.
    • (2012) Neurosci Lett , vol.506 , pp. 149-154
    • Schwab, C.1    Yu, S.2    McGeer, E.G.3    McGeer, P.L.4
  • 43
    • 84870994113 scopus 로고    scopus 로고
    • Co-aggregation of RNA binding proteins in ALS spinal motor neurons: Evidence of a common pathogenic mechanism
    • Keller BA, Volkening K, Droppelmann CA, Ang LC, Rademakers R, et al. (2012) Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism. Acta Neuropathol (Berl) 124: 733-747. doi:10.1007/s00401-012-1035-z.
    • (2012) Acta Neuropathol (Berl) , vol.124 , pp. 733-747
    • Keller, B.A.1    Volkening, K.2    Droppelmann, C.A.3    Ang, L.C.4    Rademakers, R.5
  • 44
    • 84862679022 scopus 로고    scopus 로고
    • Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease
    • Mori F, Tanji K, Toyoshima Y, Yoshida M, Kakita A, et al. (2012) Optineurin immunoreactivity in neuronal nuclear inclusions of polyglutamine diseases (Huntington's, DRPLA, SCA2, SCA3) and intranuclear inclusion body disease. Acta Neuropathol (Berl) 123: 747-749. doi:10.1007/s00401-012-0956-x.
    • (2012) Acta Neuropathol (Berl) , vol.123 , pp. 747-749
    • Mori, F.1    Tanji, K.2    Toyoshima, Y.3    Yoshida, M.4    Kakita, A.5
  • 45
    • 84857035522 scopus 로고    scopus 로고
    • Optineurin is colocalized with ubiquitin in Marinesco bodies
    • Schwab C, Yu S, McGeer PL (2012) Optineurin is colocalized with ubiquitin in Marinesco bodies. Acta Neuropathol (Berl) 123: 289-292. doi:10.1007/s00401-011-0915-y.
    • (2012) Acta Neuropathol (Berl) , vol.123 , pp. 289-292
    • Schwab, C.1    Yu, S.2    McGeer, P.L.3
  • 46
    • 64549150163 scopus 로고    scopus 로고
    • NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB
    • Sudhakar C, Nagabhushana A, Jain N, Swarup G (2009) NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB. PloS One 4: e5114. doi:10.1371/journal.pone.0005114.
    • (2009) PloS One , vol.4 , pp. e5114
    • Sudhakar, C.1    Nagabhushana, A.2    Jain, N.3    Swarup, G.4
  • 47
    • 84883739501 scopus 로고    scopus 로고
    • Optineurin suppression causes neuronal cell death via NF-κB pathway
    • Akizuki M, Yamashita H, Uemura K, Maruyama H, Kawakami H, et al. (2013) Optineurin suppression causes neuronal cell death via NF-κB pathway. J Neurochem 126: 699-704. doi:10.1111/jnc.12326.
    • (2013) J Neurochem , vol.126 , pp. 699-704
    • Akizuki, M.1    Yamashita, H.2    Uemura, K.3    Maruyama, H.4    Kawakami, H.5
  • 48
    • 34547924464 scopus 로고    scopus 로고
    • Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP
    • Zhu G, Wu CJ, Zhao Y, Ashwell JD (2007) Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP. Curr Biol CB 17: 1438-1443. doi:10.1016/j.cub.2007.07.041.
    • (2007) Curr Biol CB , vol.17 , pp. 1438-1443
    • Zhu, G.1    Wu, C.J.2    Zhao, Y.3    Ashwell, J.D.4
  • 49
    • 44649166613 scopus 로고    scopus 로고
    • Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins
    • Wagner S, Carpentier I, Rogov V, Kreike M, Ikeda F, et al. (2008) Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene 27: 3739-3745. doi:10.1038/sj.onc.1211042.
    • (2008) Oncogene , vol.27 , pp. 3739-3745
    • Wagner, S.1    Carpentier, I.2    Rogov, V.3    Kreike, M.4    Ikeda, F.5
  • 50
    • 79952325263 scopus 로고    scopus 로고
    • Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation
    • Nagabhushana A, Bansal M, Swarup G (2011) Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation. PloS One 6: e17477. doi:10.1371/journal.pone.0017477.
    • (2011) PloS One , vol.6 , pp. e17477
    • Nagabhushana, A.1    Bansal, M.2    Swarup, G.3
  • 51
    • 18544367185 scopus 로고    scopus 로고
    • Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis
    • Sahlender DA, Roberts RC, Arden SD, Spudich G, Taylor MJ, et al. (2005) Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. J Cell Biol 169: 285-295. doi:10.1083/jcb.200501162.
    • (2005) J Cell Biol , vol.169 , pp. 285-295
    • Sahlender, D.A.1    Roberts, R.C.2    Arden, S.D.3    Spudich, G.4    Taylor, M.J.5
  • 52
    • 34247148026 scopus 로고    scopus 로고
    • Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells
    • Au JSY, Puri C, Ihrke G, Kendrick-Jones J, Buss F (2007) Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells. J Cell Biol 177: 103-114. doi:10.1083/jcb.200608126.
    • (2007) J Cell Biol , vol.177 , pp. 103-114
    • Au, J.S.Y.1    Puri, C.2    Ihrke, G.3    Kendrick-Jones, J.4    Buss, F.5
  • 53
    • 65249141171 scopus 로고    scopus 로고
    • Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus
    • Del Toro D, Alberch J, Lázaro-Diéguez F, Martín-Ibáñez R, Xifró X, et al. (2009) Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus. Mol Biol Cell 20: 1478-1492. doi:10.1091/mbc.E08-07-0726.
    • (2009) Mol Biol Cell , vol.20 , pp. 1478-1492
    • Del Toro, D.1    Alberch, J.2    Lázaro-Diéguez, F.3    Martín-Ibáñez, R.4    Xifró, X.5
  • 54
    • 77249158951 scopus 로고    scopus 로고
    • Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant
    • Nagabhushana A, Chalasani ML, Jain N, Radha V, Rangaraj N, et al. (2010) Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant. BMC Cell Biol 11: 4. doi:10.1186/1471-2121-11-4.
    • (2010) BMC Cell Biol , vol.11 , pp. 4
    • Nagabhushana, A.1    Chalasani, M.L.2    Jain, N.3    Radha, V.4    Rangaraj, N.5
  • 55
    • 77954167933 scopus 로고    scopus 로고
    • Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice
    • Chi ZL, Akahori M, Obazawa M, Minami M, Noda T, et al. (2010) Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice. Hum Mol Genet 19: 2606-2615. doi:10.1093/hmg/ddq146.
    • (2010) Hum Mol Genet , vol.19 , pp. 2606-2615
    • Chi, Z.L.1    Akahori, M.2    Obazawa, M.3    Minami, M.4    Noda, T.5
  • 56
    • 77949455790 scopus 로고    scopus 로고
    • Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene
    • Ying H, Shen X, Park B, Yue BYJT (2010) Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene. PloS One 5: e9168. doi:10.1371/journal.pone.0009168.
    • (2010) PloS One , vol.5 , pp. e9168
    • Ying, H.1    Shen, X.2    Park, B.3    Yue, B.Y.J.T.4
  • 57
    • 34547914382 scopus 로고    scopus 로고
    • Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types
    • Park BC, Shen X, Samaraweera M, Yue BYJT (2006) Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types. Am J Pathol 169: 1976-1989. doi:10.2353/ajpath.2006.060400.
    • (2006) Am J Pathol , vol.169 , pp. 1976-1989
    • Park, B.C.1    Shen, X.2    Samaraweera, M.3    Yue, B.Y.J.T.4
  • 58
    • 78651087378 scopus 로고    scopus 로고
    • Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane
    • Bond LM, Peden AA, Kendrick-Jones J, Sellers JR, Buss F (2011) Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane. Mol Biol Cell 22: 54-65. doi:10.1091/mbc.E10-06-0553.
    • (2011) Mol Biol Cell , vol.22 , pp. 54-65
    • Bond, L.M.1    Peden, A.A.2    Kendrick-Jones, J.3    Sellers, J.R.4    Buss, F.5
  • 59
    • 0034649661 scopus 로고    scopus 로고
    • FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis
    • Hattula K, Peränen J (2000) FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis. Curr Biol CB 10: 1603-1606.
    • (2000) Curr Biol CB , vol.10 , pp. 1603-1606
    • Hattula, K.1    Peränen, J.2
  • 60
    • 84872228715 scopus 로고    scopus 로고
    • Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17
    • Vaibhava V, Nagabhushana A, Chalasani MLS, Sudhakar C, Kumari A, et al. (2012) Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17. J Cell Sci 125: 5026-5039. doi:10.1242/jcs.102327.
    • (2012) J Cell Sci , vol.125 , pp. 5026-5039
    • Vaibhava, V.1    Nagabhushana, A.2    Chalasani, M.L.S.3    Sudhakar, C.4    Kumari, A.5
  • 61
    • 84899680397 scopus 로고    scopus 로고
    • E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy
    • Chalasani MLS, Kumari A, Radha V, Swarup G (2014) E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy. PloS One 9: e95758. doi:10.1371/journal.pone.0095758.
    • (2014) PloS One , vol.9 , pp. e95758
    • Chalasani, M.L.S.1    Kumari, A.2    Radha, V.3    Swarup, G.4
  • 62
    • 79960804104 scopus 로고    scopus 로고
    • Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
    • Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, et al. (2011) Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science 333: 228-233. doi:10.1126/science.1205405.
    • (2011) Science , vol.333 , pp. 228-233
    • Wild, P.1    Farhan, H.2    McEwan, D.G.3    Wagner, S.4    Rogov, V.V.5
  • 63
    • 84876085831 scopus 로고    scopus 로고
    • Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
    • Korac J, Schaeffer V, Kovacevic I, Clement AM, Jungblut B, et al. (2013) Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J Cell Sci 126: 580-592. doi:10.1242/jcs.114926.
    • (2013) J Cell Sci , vol.126 , pp. 580-592
    • Korac, J.1    Schaeffer, V.2    Kovacevic, I.3    Clement, A.M.4    Jungblut, B.5
  • 64
    • 84867103427 scopus 로고    scopus 로고
    • Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome
    • Tumbarello DA, Waxse BJ, Arden SD, Bright NA, Kendrick-Jones J, et al. (2012) Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. Nat Cell Biol 14: 1024-1035. doi:10.1038/ncb2589.
    • (2012) Nat Cell Biol , vol.14 , pp. 1024-1035
    • Tumbarello, D.A.1    Waxse, B.J.2    Arden, S.D.3    Bright, N.A.4    Kendrick-Jones, J.5
  • 65
    • 84857437068 scopus 로고    scopus 로고
    • Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression
    • Kachaner D, Filipe J, Laplantine E, Bauch A, Bennett KL, et al. (2012) Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression. Mol Cell 45: 553-566. doi:10.1016/j.molcel.2011.12.030.
    • (2012) Mol Cell , vol.45 , pp. 553-566
    • Kachaner, D.1    Filipe, J.2    Laplantine, E.3    Bauch, A.4    Bennett, K.L.5
  • 66
    • 27144523294 scopus 로고    scopus 로고
    • Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin
    • Anborgh PH, Godin C, Pampillo M, Dhami GK, Dale LB, et al. (2005) Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin. J Biol Chem 280: 34840-34848. doi:10.1074/jbc.M504508200.
    • (2005) J Biol Chem , vol.280 , pp. 34840-34848
    • Anborgh, P.H.1    Godin, C.2    Pampillo, M.3    Dhami, G.K.4    Dale, L.B.5
  • 67
    • 55349084412 scopus 로고    scopus 로고
    • A function of huntingtin in guanine nucleotide exchange on Rab11
    • Li X, Sapp E, Valencia A, Kegel KB, Qin ZH, et al. (2008) A function of huntingtin in guanine nucleotide exchange on Rab11. Neuroreport 19: 1643-1647. doi:10.1097/WNR.0b013e328315cd4c.
    • (2008) Neuroreport , vol.19 , pp. 1643-1647
    • Li, X.1    Sapp, E.2    Valencia, A.3    Kegel, K.B.4    Qin, Z.H.5
  • 68
    • 81355148875 scopus 로고    scopus 로고
    • Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins
    • Sippl C, Bosserhoff AK, Fischer D, Tamm ER (2011) Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins. Exp Eye Res 93: 669-680. doi:10.1016/j.exer.2011.08.011.
    • (2011) Exp Eye Res , vol.93 , pp. 669-680
    • Sippl, C.1    Bosserhoff, A.K.2    Fischer, D.3    Tamm, E.R.4
  • 69
    • 84862908221 scopus 로고    scopus 로고
    • Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells
    • Li H, Ao X, Jia J, Wang Q, Zhang Z (2011) Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells. Mol Vis 17: 3314-3325.
    • (2011) Mol Vis , vol.17 , pp. 3314-3325
    • Li, H.1    Ao, X.2    Jia, J.3    Wang, Q.4    Zhang, Z.5
  • 70
    • 77956480550 scopus 로고    scopus 로고
    • Myosin VI and optineurin are required for polarized EGFR delivery and directed migration
    • Chibalina MV, Poliakov A, Kendrick-Jones J, Buss F (2010) Myosin VI and optineurin are required for polarized EGFR delivery and directed migration. Traffic Cph Den 11: 1290-1303. doi:10.1111/j.1600-0854.2010.01101.x.
    • (2010) Traffic Cph Den , vol.11 , pp. 1290-1303
    • Chibalina, M.V.1    Poliakov, A.2    Kendrick-Jones, J.3    Buss, F.4
  • 71
    • 80053917869 scopus 로고    scopus 로고
    • Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β
    • Gleason CE, Ordureau A, Gourlay R, Arthur JSC, Cohen P (2011) Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β. J Biol Chem 286: 35663-35674. doi:10.1074/jbc.M111.267567.
    • (2011) J Biol Chem , vol.286 , pp. 35663-35674
    • Gleason, C.E.1    Ordureau, A.2    Gourlay, R.3    Arthur, J.S.C.4    Cohen, P.5
  • 72
    • 84890424048 scopus 로고    scopus 로고
    • Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells
    • Munitic I, Giardino Torchia ML, Meena NP, Zhu G, Li CC, et al. (2013) Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells. J Immunol Baltim Md 1950 191: 6231-6240. doi:10.4049/jimmunol.1301696.
    • (2013) J Immunol Baltim Md , vol.1950 , Issue.191 , pp. 6231-6240
    • Munitic, I.1    Giardino Torchia, M.L.2    Meena, N.P.3    Zhu, G.4    Li, C.C.5
  • 73
    • 84860329157 scopus 로고    scopus 로고
    • Transgenic mice with overexpression of mutated human optineurin (E50K) in the retina
    • Meng Q, Xiao Z, Yuan H, Xue F, Zhu Y, et al. (2012) Transgenic mice with overexpression of mutated human optineurin (E50K) in the retina. Mol Biol Rep 39: 1119-1124. doi:10.1007/s11033-011-0840-0.
    • (2012) Mol Biol Rep , vol.39 , pp. 1119-1124
    • Meng, Q.1    Xiao, Z.2    Yuan, H.3    Xue, F.4    Zhu, Y.5
  • 76
    • 36448963734 scopus 로고    scopus 로고
    • The Tol2kit: A multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
    • Kwan KM, Fujimoto E, Grabher C, Mangum BD, Hardy ME, et al. (2007) The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs. Dev Dyn Off Publ Am Assoc Anat 236: 3088-3099. doi:10.1002/dvdy.21343.
    • (2007) Dev Dyn off Publ Am Assoc Anat , vol.236 , pp. 3088-3099
    • Kwan, K.M.1    Fujimoto, E.2    Grabher, C.3    Mangum, B.D.4    Hardy, M.E.5
  • 77
    • 77951076167 scopus 로고    scopus 로고
    • Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development
    • Insinna C, Baye LM, Amsterdam A, Besharse JC, Link BA (2010) Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development. Neural Develop 5: 12. doi:10.1186/1749-8104-5-12.
    • (2010) Neural Develop , vol.5 , pp. 12
    • Insinna, C.1    Baye, L.M.2    Amsterdam, A.3    Besharse, J.C.4    Link, B.A.5
  • 78
    • 16644391315 scopus 로고    scopus 로고
    • Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element
    • Kawakami K (2004) Transgenesis and gene trap methods in zebrafish by using the Tol2 transposable element. Methods Cell Biol 77: 201-222.
    • (2004) Methods Cell Biol , vol.77 , pp. 201-222
    • Kawakami, K.1
  • 79
    • 25444488956 scopus 로고    scopus 로고
    • Transposon tools and methods in zebrafish
    • Kawakami K (2005) Transposon tools and methods in zebrafish. Dev Dyn Off Publ Am Assoc Anat 234: 244-254. doi:10.1002/dvdy.20516.
    • (2005) Dev Dyn off Publ Am Assoc Anat , vol.234 , pp. 244-254
    • Kawakami, K.1
  • 80
    • 29644439510 scopus 로고    scopus 로고
    • Cellular and molecular analyses of vascular tube and lumen formation in zebrafish
    • Jin SW, Beis D, Mitchell T, Chen JN, Stainier DYR (2005) Cellular and molecular analyses of vascular tube and lumen formation in zebrafish. Dev Camb Engl 132: 5199-5209. doi:10.1242/dev.02087.
    • (2005) Dev Camb Engl , vol.132 , pp. 5199-5209
    • Jin, S.W.1    Beis, D.2    Mitchell, T.3    Chen, J.N.4    Stainier, D.Y.R.5
  • 82
    • 84866928522 scopus 로고    scopus 로고
    • What evidence is there for the homology of protein-protein interactions?
    • Lewis ACF, Jones NS, Porter MA, Deane CM (2012) What evidence is there for the homology of protein-protein interactions? PLoS Comput Biol 8: e1002645. doi:10.1371/journal.pcbi.1002645.
    • (2012) PLoS Comput Biol , vol.8 , pp. e1002645
    • Lewis, A.C.F.1    Jones, N.S.2    Porter, M.A.3    Deane, C.M.4
  • 83
    • 38149126474 scopus 로고    scopus 로고
    • High-resolution in situ hybridization to whole-mount zebrafish embryos
    • Thisse C, Thisse B (2008) High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc 3: 59-69. doi:10.1038/nprot.2007.514.
    • (2008) Nat Protoc , vol.3 , pp. 59-69
    • Thisse, C.1    Thisse, B.2
  • 84
    • 4744376056 scopus 로고    scopus 로고
    • Repulsion and attraction of axons by semaphorin3D are mediated by different neuropilins in vivo
    • Wolman MA, Liu Y, Tawarayama H, Shoji W, Halloran MC (2004) Repulsion and attraction of axons by semaphorin3D are mediated by different neuropilins in vivo. J Neurosci Off J Soc Neurosci 24: 8428-8435. doi:10.1523/JNEUROSCI.2349-04.2004.
    • (2004) J Neurosci off J Soc Neurosci , vol.24 , pp. 8428-8435
    • Wolman, M.A.1    Liu, Y.2    Tawarayama, H.3    Shoji, W.4    Halloran, M.C.5
  • 85
    • 0036932948 scopus 로고    scopus 로고
    • Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues
    • Zeller J, Schneider V, Malayaman S, Higashijima S, Okamoto H, et al. (2002) Migration of zebrafish spinal motor nerves into the periphery requires multiple myotome-derived cues. Dev Biol 252: 241-256.
    • (2002) Dev Biol , vol.252 , pp. 241-256
    • Zeller, J.1    Schneider, V.2    Malayaman, S.3    Higashijima, S.4    Okamoto, H.5
  • 86
    • 79952256057 scopus 로고    scopus 로고
    • Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma
    • Veth KN, Willer JR, Collery RF, Gray MP, Willer GB, et al. (2011) Mutations in zebrafish lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma. PLoS Genet 7: e1001310. doi:10.1371/journal.pgen.1001310.
    • (2011) PLoS Genet , vol.7 , pp. e1001310
    • Veth, K.N.1    Willer, J.R.2    Collery, R.F.3    Gray, M.P.4    Willer, G.B.5
  • 87
    • 0025317419 scopus 로고
    • Characterization of polymerase chain reaction amplification of specific alleles
    • Sarkar G, Cassady J, Bottema CD, Sommer SS (1990) Characterization of polymerase chain reaction amplification of specific alleles. Anal Biochem 186: 64-68.
    • (1990) Anal Biochem , vol.186 , pp. 64-68
    • Sarkar, G.1    Cassady, J.2    Bottema, C.D.3    Sommer, S.S.4
  • 88
    • 48249142323 scopus 로고    scopus 로고
    • The primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway
    • Skarie JM, Link BA (2008) The primary open-angle glaucoma gene WDR36 functions in ribosomal RNA processing and interacts with the p53 stress-response pathway. Hum Mol Genet 17: 2474-2485. doi:10.1093/hmg/ddn147.
    • (2008) Hum Mol Genet , vol.17 , pp. 2474-2485
    • Skarie, J.M.1    Link, B.A.2
  • 89
    • 0033562350 scopus 로고    scopus 로고
    • Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
    • Winer J, Jung CK, Shackel I, Williams PM (1999) Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 270: 41-49. doi:10.1006/abio.1999.4085.
    • (1999) Anal Biochem , vol.270 , pp. 41-49
    • Winer, J.1    Jung, C.K.2    Shackel, I.3    Williams, P.M.4
  • 90
    • 84962028766 scopus 로고    scopus 로고
    • Time Course Analysis of Gene Expression Patterns in Zebrafish Eye During Optic Nerve Regeneration
    • McCurley AT, Callard GV (2010) Time Course Analysis of Gene Expression Patterns in Zebrafish Eye During Optic Nerve Regeneration. J Exp Neurosci 2010: 17-33.
    • (2010) J Exp Neurosci , vol.2010 , pp. 17-33
    • McCurley, A.T.1    Callard, G.V.2
  • 91
    • 79957829368 scopus 로고    scopus 로고
    • Activation of cytokine expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus-infected cells
    • Wang WL, Liu W, Gong HY, Hong JR, Lin CC, et al. (2011) Activation of cytokine expression occurs through the TNFα/NF-κB-mediated pathway in birnavirus-infected cells. Fish Shellfish Immunol 31: 10-21. doi:10.1016/j.fsi.2011.01.015.
    • (2011) Fish Shellfish Immunol , vol.31 , pp. 10-21
    • Wang, W.L.1    Liu, W.2    Gong, H.Y.3    Hong, J.R.4    Lin, C.C.5
  • 92
    • 77957756246 scopus 로고    scopus 로고
    • Effect of the temperature during antiviral immune response ontogeny in teleosts
    • Dios S, Romero A, Chamorro R, Figueras A, Novoa B (2010) Effect of the temperature during antiviral immune response ontogeny in teleosts. Fish Shellfish Immunol 29: 1019-1027. doi:10.1016/j.fsi.2010.08.006.
    • (2010) Fish Shellfish Immunol , vol.29 , pp. 1019-1027
    • Dios, S.1    Romero, A.2    Chamorro, R.3    Figueras, A.4    Novoa, B.5
  • 96
    • 78649436084 scopus 로고    scopus 로고
    • FoxC1 is essential for vascular basement membrane integrity and hyaloid vessel morphogenesis
    • Skarie JM, Link BA (2009) FoxC1 is essential for vascular basement membrane integrity and hyaloid vessel morphogenesis. Invest Ophthalmol Vis Sci 50: 5026-5034. doi:10.1167/iovs.09-3447.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 5026-5034
    • Skarie, J.M.1    Link, B.A.2
  • 97
    • 84857387139 scopus 로고    scopus 로고
    • Cellular and molecular biology of optineurin
    • Ying H, Yue BYJT (2012) Cellular and molecular biology of optineurin. Int Rev Cell Mol Biol 294: 223-258. doi:10.1016/B978-0-12-394305-7.00005-7.
    • (2012) Int Rev Cell Mol Biol , vol.294 , pp. 223-258
    • Ying, H.1    Yue, B.Y.J.T.2
  • 98
    • 40149097099 scopus 로고    scopus 로고
    • Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma
    • Morton S, Hesson L, Peggie M, Cohen P (2008) Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma. FEBS Lett 582: 997-1002. doi:10.1016/j.febslet.2008.02.047.
    • (2008) FEBS Lett , vol.582 , pp. 997-1002
    • Morton, S.1    Hesson, L.2    Peggie, M.3    Cohen, P.4
  • 99
    • 84892990819 scopus 로고    scopus 로고
    • Interaction between optineurin and the bZIP transcription factor NRL
    • Wang C, Hosono K, Ohtsubo M, Ohishi K, Gao J, et al. (2014) Interaction between optineurin and the bZIP transcription factor NRL. Cell Biol Int 38: 16-25. doi:10.1002/cbin.10174.
    • (2014) Cell Biol Int , vol.38 , pp. 16-25
    • Wang, C.1    Hosono, K.2    Ohtsubo, M.3    Ohishi, K.4    Gao, J.5
  • 100
    • 84883369848 scopus 로고    scopus 로고
    • Structural basis for phosphorylation-triggered autophagic clearance of Salmonella
    • Rogov VV, Suzuki H, Fiskin E, Wild P, Kniss A, et al. (2013) Structural basis for phosphorylation-triggered autophagic clearance of Salmonella. Biochem J 454: 459-466. doi:10.1042/BJ20121907.
    • (2013) Biochem J , vol.454 , pp. 459-466
    • Rogov, V.V.1    Suzuki, H.2    Fiskin, E.3    Wild, P.4    Kniss, A.5
  • 102
    • 0242458482 scopus 로고
    • Protein disorder prediction: Implications for structural proteomics
    • Linding R, Jensen LJ, Diella F, Bork P, Gibson TJ, et al. (2003) Protein disorder prediction: implications for structural proteomics. Struct Lond Engl 1993 11: 1453-1459.
    • (1993) Struct Lond Engl , vol.11 , pp. 1453-1459
    • Linding, R.1    Jensen, L.J.2    Diella, F.3    Bork, P.4    Gibson, T.J.5
  • 103
    • 33744912793 scopus 로고    scopus 로고
    • Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus
    • De Marco N, Buono M, Troise F, Diez-Roux G (2006) Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus. J Biol Chem 281: 16147-16156. doi:10.1074/jbc.M601467200.
    • (2006) J Biol Chem , vol.281 , pp. 16147-16156
    • De Marco, N.1    Buono, M.2    Troise, F.3    Diez-Roux, G.4
  • 104
    • 10644285603 scopus 로고    scopus 로고
    • Molecular cloning, genomic structure, and protein characterization of mouse optineurin
    • Rezaie T, Sarfarazi M (2005) Molecular cloning, genomic structure, and protein characterization of mouse optineurin. Genomics 85: 131-138. doi:10.1016/j.ygeno.2004.10.011.
    • (2005) Genomics , vol.85 , pp. 131-138
    • Rezaie, T.1    Sarfarazi, M.2
  • 105
    • 34248402037 scopus 로고    scopus 로고
    • A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants
    • Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, et al. (2007) A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants. Invest Ophthalmol Vis Sci 48: 1607-1614. doi:10.1167/iovs.06-0834.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 1607-1614
    • Chalasani, M.L.1    Radha, V.2    Gupta, V.3    Agarwal, N.4    Balasubramanian, D.5
  • 106
    • 84892808067 scopus 로고    scopus 로고
    • Clinicopathologic features of autosomal recessive amyotrophic lateral sclerosis associated with optineurin mutation
    • Kamada M, Izumi Y, Ayaki T, Nakamura M, Kagawa S, et al. (2014) Clinicopathologic features of autosomal recessive amyotrophic lateral sclerosis associated with optineurin mutation. Neuropathol Off J Jpn Soc Neuropathol 34: 64-70. doi:10.1111/neup.12051.
    • (2014) Neuropathol off J Jpn Soc Neuropathol , vol.34 , pp. 64-70
    • Kamada, M.1    Izumi, Y.2    Ayaki, T.3    Nakamura, M.4    Kagawa, S.5
  • 107
    • 0024994033 scopus 로고
    • Primary neurons that express the L2/HNK-1 carbohydrate during early development in the zebrafish
    • Metcalfe WK, Myers PZ, Trevarrow B, Bass MB, Kimmel CB (1990) Primary neurons that express the L2/HNK-1 carbohydrate during early development in the zebrafish. Dev Camb Engl 110: 491-504.
    • (1990) Dev Camb Engl , vol.110 , pp. 491-504
    • Metcalfe, W.K.1    Myers, P.Z.2    Trevarrow, B.3    Bass, M.B.4    Kimmel, C.B.5
  • 108
    • 73949131698 scopus 로고    scopus 로고
    • Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth
    • Koga T, Shen X, Park JS, Qiu Y, Park BC, et al. (2010) Differential effects of myocilin and optineurin, two glaucoma genes, on neurite outgrowth. Am J Pathol 176: 343-352. doi:10.2353/ajpath.2010.090194.
    • (2010) Am J Pathol , vol.176 , pp. 343-352
    • Koga, T.1    Shen, X.2    Park, J.S.3    Qiu, Y.4    Park, B.C.5
  • 109
    • 0032498607 scopus 로고    scopus 로고
    • Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons
    • Nakata T, Terada S, Hirokawa N (1998) Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons. J Cell Biol 140: 659-674.
    • (1998) J Cell Biol , vol.140 , pp. 659-674
    • Nakata, T.1    Terada, S.2    Hirokawa, N.3
  • 110
    • 49949086671 scopus 로고    scopus 로고
    • Controlling morpholino experiments: Don't stop making antisense
    • Eisen JS, Smith JC (2008) Controlling morpholino experiments: don't stop making antisense. Dev Camb Engl 135: 1735-1743. doi:10.1242/dev.001115.
    • (2008) Dev Camb Engl , vol.135 , pp. 1735-1743
    • Eisen, J.S.1    Smith, J.C.2
  • 111
    • 84867400662 scopus 로고    scopus 로고
    • Critical pathogenic events underlying progression of neurodegeneration in glaucoma
    • Calkins DJ (2012) Critical pathogenic events underlying progression of neurodegeneration in glaucoma. Prog Retin Eye Res 31: 702-719. doi:10.1016/j.preteyeres.2012.07.001.
    • (2012) Prog Retin Eye Res , vol.31 , pp. 702-719
    • Calkins, D.J.1
  • 112
    • 84870812784 scopus 로고    scopus 로고
    • Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target
    • Crish SD, Dapper JD, MacNamee SE, Balaram P, Sidorova TN, et al. (2013) Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target. Neuroscience 229: 55-70. doi:10.1016/j.neuroscience.2012.10.069.
    • (2013) Neuroscience , vol.229 , pp. 55-70
    • Crish, S.D.1    Dapper, J.D.2    MacNamee, S.E.3    Balaram, P.4    Sidorova, T.N.5
  • 113
    • 48249102303 scopus 로고    scopus 로고
    • Role of axonal transport in neurodegenerative diseases
    • De Vos KJ, Grierson AJ, Ackerley S, Miller CCJ (2008) Role of axonal transport in neurodegenerative diseases. Annu Rev Neurosci 31: 151-173. doi:10.1146/annurev.neuro.31.061307.090711.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 151-173
    • De Vos, K.J.1    Grierson, A.J.2    Ackerley, S.3    Miller, C.C.J.4
  • 114
    • 84878900746 scopus 로고    scopus 로고
    • Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase
    • Morfini GA, Bosco DA, Brown H, Gatto R, Kaminska A, et al. (2013) Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase. PloS One 8: e65235. doi:10.1371/journal.pone.0065235.
    • (2013) PloS One , vol.8 , pp. e65235
    • Morfini, G.A.1    Bosco, D.A.2    Brown, H.3    Gatto, R.4    Kaminska, A.5
  • 115
    • 84858259015 scopus 로고    scopus 로고
    • Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis
    • Marinkovic P, Reuter MS, Brill MS, Godinho L, Kerschensteiner M, et al. (2012) Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 109: 4296-4301. doi:10.1073/pnas.1200658109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 4296-4301
    • Marinkovic, P.1    Reuter, M.S.2    Brill, M.S.3    Godinho, L.4    Kerschensteiner, M.5
  • 117
    • 84055217271 scopus 로고    scopus 로고
    • Molecular motor proteins and amyotrophic lateral sclerosis
    • Soo KY, Farg M, Atkin JD (2011) Molecular motor proteins and amyotrophic lateral sclerosis. Int J Mol Sci 12: 9057-9082. doi:10.3390/ijms12129057.
    • (2011) Int J Mol Sci , vol.12 , pp. 9057-9082
    • Soo, K.Y.1    Farg, M.2    Atkin, J.D.3


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