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Volumn 126, Issue 6, 2013, Pages 699-704

Optineurin suppression causes neuronal cell death via NF-κB pathway

Author keywords

amyotrophic lateral sclerosis; NF B; optineurin

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OPTINEURIN; SMALL INTERFERING RNA; WITHAFERIN A;

EID: 84883739501     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12326     Document Type: Article
Times cited : (78)

References (23)
  • 2
    • 77954167933 scopus 로고    scopus 로고
    • Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice
    • Chi Z. L., Akahori M., Obazawa M., et al,. (2010) Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice. Hum. Mol. Genet. 19, 2606-2615.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 2606-2615
    • Chi, Z.L.1    Akahori, M.2    Obazawa, M.3
  • 3
    • 0034656846 scopus 로고    scopus 로고
    • Cerebral ischemia: Gene activation, neuronal injury, and the protective role of antioxidants
    • Clemens J. A., (2000) Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants. Free Radic. Biol. Med. 28, 1526-1531.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1526-1531
    • Clemens, J.A.1
  • 4
    • 80053629733 scopus 로고    scopus 로고
    • Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis
    • Del Bo R., Tiloca C., Pensato V., et al,. (2011) Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry 82, 1239-1243.
    • (2011) J. Neurol. Neurosurg. Psychiatry , vol.82 , pp. 1239-1243
    • Del Bo, R.1    Tiloca, C.2    Pensato, V.3
  • 6
    • 0041833409 scopus 로고    scopus 로고
    • Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis
    • Hensley K., Fedynyshyn J., Ferrell S., et al,. (2003) Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis. Neurobiol. Dis. 14, 74-80.
    • (2003) Neurobiol. Dis. , vol.14 , pp. 74-80
    • Hensley, K.1    Fedynyshyn, J.2    Ferrell, S.3
  • 7
    • 79954581188 scopus 로고    scopus 로고
    • Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease
    • Ito H., Fujita K., Nakamura M., et al,. (2011) Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease. Acta Neuropathol. 121, 555-557.
    • (2011) Acta Neuropathol. , vol.121 , pp. 555-557
    • Ito, H.1    Fujita, K.2    Nakamura, M.3
  • 8
    • 0027453548 scopus 로고
    • Promoter analysis of the gene encoding the i kappa B-alpha/MAD3 inhibitor of NF-kappa B: Positive regulation by members of the rel/NF-kappa B family
    • Le Bail O., Schmidt-Ullrich R., and, Israel A., (1993) Promoter analysis of the gene encoding the I kappa B-alpha/MAD3 inhibitor of NF-kappa B: positive regulation by members of the rel/NF-kappa B family. EMBO J. 12, 5043-5049.
    • (1993) EMBO J. , vol.12 , pp. 5043-5049
    • Le Bail, O.1    Schmidt-Ullrich, R.2    Israel, A.3
  • 9
    • 33645472043 scopus 로고    scopus 로고
    • On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies
    • LePage K. T., Dickey R. W., Gerwick W. H., Jester E. L., and, Murray T. F., (2005) On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies. Crit. Rev. Neurobiol. 17, 27-50.
    • (2005) Crit. Rev. Neurobiol. , vol.17 , pp. 27-50
    • Lepage, K.T.1    Dickey, R.W.2    Gerwick, W.H.3    Jester, E.L.4    Murray, T.F.5
  • 10
    • 84862908221 scopus 로고    scopus 로고
    • Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells
    • Li H., Ao X., Jia J., Wang Q., and, Zhang Z., (2011) Effects of optineurin siRNA on apoptotic genes and apoptosis in RGC-5 cells. Mol. Vis. 17, 3314-3325.
    • (2011) Mol. Vis. , vol.17 , pp. 3314-3325
    • Li, H.1    Ao, X.2    Jia, J.3    Wang, Q.4    Zhang, Z.5
  • 11
    • 0034517935 scopus 로고    scopus 로고
    • P53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis
    • Martin L. J., (2000) p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis. Neurobiol. Dis. 7, 613-622.
    • (2000) Neurobiol. Dis. , vol.7 , pp. 613-622
    • Martin, L.J.1
  • 12
    • 77952419246 scopus 로고    scopus 로고
    • Mutations of optineurin in amyotrophic lateral sclerosis
    • Maruyama H., Morino H., Ito H., et al,. (2010) Mutations of optineurin in amyotrophic lateral sclerosis. Nature 465, 223-226.
    • (2010) Nature , vol.465 , pp. 223-226
    • Maruyama, H.1    Morino, H.2    Ito, H.3
  • 13
    • 79952898709 scopus 로고    scopus 로고
    • Screening of OPTN in French familial amyotrophic lateral sclerosis
    • Millecamps S., Boillee S., Chabrol E., et al,. (2011) Screening of OPTN in French familial amyotrophic lateral sclerosis. Neurobiol. Aging 32, 557.e11-557.e13.
    • (2011) Neurobiol. Aging , vol.32
    • Millecamps, S.1    Boillee, S.2    Chabrol, E.3
  • 14
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., and, Reed J. C., (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80, 293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 16
    • 0034733968 scopus 로고    scopus 로고
    • Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis
    • Poloni M., Facchetti D., Mai R., et al,. (2000) Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis. Neurosci. Lett. 287, 211-214.
    • (2000) Neurosci. Lett. , vol.287 , pp. 211-214
    • Poloni, M.1    Facchetti, D.2    Mai, R.3
  • 17
    • 18244385269 scopus 로고    scopus 로고
    • Adult-onset primary open-angle glaucoma caused by mutations in optineurin
    • Rezaie T., Child A., Hitchings R., et al,. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science 295, 1077-1079.
    • (2002) Science , vol.295 , pp. 1077-1079
    • Rezaie, T.1    Child, A.2    Hitchings, R.3
  • 18
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen D. R., Siddique T., Patterson D., et al,. (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3
  • 20
    • 81355148875 scopus 로고    scopus 로고
    • Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins
    • Sippl C., Bosserhoff A. K., Fischer D., and, Tamm E. R., (2011) Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins. Exp. Eye Res. 93, 669-680.
    • (2011) Exp. Eye Res. , vol.93 , pp. 669-680
    • Sippl, C.1    Bosserhoff, A.K.2    Fischer, D.3    Tamm, E.R.4
  • 21
    • 84855515796 scopus 로고    scopus 로고
    • Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor kappaB-mediated pathogenic pathways
    • Swarup V., Phaneuf D., Dupre N., Petri S., Strong M., Kriz J., and, Julien J. P., (2011) Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor kappaB-mediated pathogenic pathways. J. Exp. Med. 208, 2429-2447.
    • (2011) J. Exp. Med. , vol.208 , pp. 2429-2447
    • Swarup, V.1    Phaneuf, D.2    Dupre, N.3    Petri, S.4    Strong, M.5    Kriz, J.6    Julien, J.P.7
  • 23
    • 0036269810 scopus 로고    scopus 로고
    • Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
    • Yoshihara T., Ishigaki S., Yamamoto M., Liang Y., Niwa J., Takeuchi H., Doyu M., and, Sobue G., (2002) Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J. Neurochem. 80, 158-167.
    • (2002) J. Neurochem. , vol.80 , pp. 158-167
    • Yoshihara, T.1    Ishigaki, S.2    Yamamoto, M.3    Liang, Y.4    Niwa, J.5    Takeuchi, H.6    Doyu, M.7    Sobue, G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.