NF-κB mediates tumor necrosis factor α-induced expression of optineurin, a negative regulator of NF-κB

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Sudhakar, Cherukuri ^a   Nagabhushana, Ananthamurthy ^a   Jain, Nishant ^a   Swarup, Ghanshyam ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OPTINEURIN; REGULATOR PROTEIN; SHORT HAIRPIN RNA; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; OPTN PROTEIN, HUMAN; TRANSCRIPTION FACTOR IIIA; UBIQUITIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN QUATERNARY STRUCTURE; REGULATORY MECHANISM; GENETICS; HELA CELL; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

BASE SEQUENCE; BINDING SITES; DNA, COMPLEMENTARY; DOWN-REGULATION; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTOR TFIIIA; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN;

EID: 64549150163     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005114     Document Type: Article

References (40)

1. Li Y, Kang J, Horwitz MS (1998) Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains. Mol Cell Biol 18: 1601-1610.
2. Rezaie T, Waitzman DM, Seeman JL, Kaufman PL, Sarfarazi M (2005) Molecular cloning and expression profiling of optineurin in the Rhesus monkey. Invest Ophthalmol Vis Sci 46: 2404-2410.
3. Kroeber M, Ohlmann A, Russell P, Tamm ER (2006) Transgenic studies on the role of optineurin in the mouse eye. Exp Eye Res 82: 1075-1085.
4. De Marco N, Buon M, Troise F, Diez-Roux G (2006) Optineurin increases cell survival and translocates to the nucleus in a RAB8 dependent manner upon an apoptotic stimulus. J Biol Chem 281: 16147-16156.
5. Quigley HA (1999) Neuronal death in glaucoma. Prog Retin Eye Res 18: 39-57.
6. Rezaie T, Child A, Hitchings R, Brice G, Miller L, et al. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin. Science 295: 1077-1079.
7. Willoughby CE, Chann LL, Herd S, Billingsley G, Noordeh N, et al. (2004) Defining the pathogenicity of optineurin in juvenile open-angle glaucoma. Invest Ophthalmol Vis Sci 45: 3122-3130.
8. Leung YF, Fan BJ, Lam DS, Lee WS, Tam PO, et al. (2003) Different optineurin mutation pattern in primary open-angle glaucoma. Invest Ophthalmol Vis Sci 44: 3880-3884.
9. Fuse N, Takahashi K, Akiyama H, Nakazawa T, Seimiya M, et al. (2004) Molecular genetic analysis of optineurin gene for primary open-angle and normal tension glaucoma in the Japanese population. J Glaucoma 13: 299-303.
10. Alward WL, Kwon YH, Kawase K, Craig JE, Hayreh SS, et al. (2003) Evaluation of optineurin sequence variation in 1048 patients with open-angle glaucoma. Am J Ophthalmol 136: 904-910.
11. Funayama T, Ishikawa K, Ohtake Y, Tanino T, Kurosaka D, et al. (2004) Variants in optineurin gene and their association with tumor necrosis factor-α polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci 45: 4359-4367.
12. Mukhopadhyay A, Komatireddy S, Acharya M, Bhattacharjee A, Mandal AK, et al. (2005) Evaluation of optineurin as a candidate gene in Indian patients with primary open-angle glaucoma. Mol Vision 11: 792-797.
13. Aung T, Rezaie T, Okada K, Viswanathan AC, Child AH, et al. (2005) Clinical features and course of patients with glaucoma with the E50K mutation in the optineurin gene. Invest Ophthalmol Vis Sci 46: 2816-2822.
14. Sarfarazi M, Rezaie T (2003) Optineurin in primary open-angle glaucoma. Ophthalmol Clin North Am 16: 529-541.
15. Hattula K, Paranen J (2000) FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis. Curr Biol 10: 1603-1606.
16. Schwamborn K, Weil R, Courtois G, Whiteside ST, Israel A (2000) Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway. J Biol Chem 275: 22780-22789.
17. Sahlender DA, Roberts RC, Arden SD, Spudich G, Taylor MJ, et al. (2005) Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. J Cell Biol 169: 285-295.
18. Anborgh PH, Godin C, Pampillo M, Dhami GK, Dale LB, et al. (2005) Inhibition of metabotropic glutamate receptor signaling by the Huntingtin-binding protein optineurin. J Biol Chem 280: 4840-4848.
19. Zhu G, Wu CJ, Zhao Y, Ashwell JD (2007) Optineurin negatively regulates TNFα-induced NF-κB activation by competing with NEMO for ubiquitinated RIP. Curr Bio 17: 1438-1443.
20. Morton S, Hesson L, Peggie M, Cohen P (2008) Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma. FEBS Letters 582: 997-1002.
21. Weisschuh N, Alavi MV, Bonin M, Wissinger B (2007) Identification of genes that are linked with optineurin expression using a combined RNAi-microarray approach. Exp Eye Res 85: 450-61.
22. Wajant H, Pfizenmaier K, Scheurich P (2003) Tumor necrosis factor signaling. Cell Death Differ 10: 45-65.
23. Chen C, Goeddel DV (2002) TNF-R1 signalling: A beautiful pathway. Science 296: 1634-1635.
24. Wang N, Chintala SK, Fini ME, Schuman JS (2001) Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nature Med 7: 304-309.
25. Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, et al. (2007) A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants. Invest Ophthalmol Vis Sci 48: 1607-1614.
26. Fiedler MA, Wernke-Dollries K, Stark JM (1998) Inhibition of TNFα-induced NF-κB activation and IL-8 release in A549 cells with the proteasome inhibitor MG132. Am J Repir Cell Mol Biol 19: 259-268.
27. Jono H, Lim JH, Chen LF, Xu H, Trompouki E, et al. (2004) NF-κB is essential for induction of CYLD, the negative regulator of NF-κB. J Biol Chem 279: 36171-36174.
28. Mrowka R, Bluthgen N, Fahling M (2008) Seed-based discovery of specific transcription factor target genes. FEBS Journal 275: 3178-3192.
29. Takahashi Y, Katai N, Murata T, Taniguchi SI, Hayashi T (2007) Development of spontaneous optic neuropathy in NF-κB p50-deficient mice: requirement for NF-κB p50 in ganglion cell survival. Neuropathology and Applied Neurobiology 33: 692-705.
30. Aggarwal BB (2004) Nuclear factor-κB: The enemy within. Cancer Cell 6: 203-208.
31. Karin M (2006) Nuclear factor-κB in cancer development and progression. Nature 441: 431-436.
32. Boye K, Grotterod I, Aasheim HC, Hovig E, Maelandsmo GM (2008) Activation of NF- kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes. Int J Cancer 123(6): 1301-1310.
33. Jain N, Gupta S, Sudhakar Ch, Radha V, Swarup G (2005) Role of p73 in regulating human caspase-1 gene transcription induced by interferon-γ and cisplatin. J Biol Chem 280: 36664-36673.
34. Anto RJ, Venkatraman M, Karunagaran D (2003) Inhibition of NF-κB sensitizes A431 cells to epidermal growth factor-induced apoptosis, whereas its activation by ectopic expression of RelA confers resistance. J Biol Chem 278: 25490-25498.
35. Chaturvedi MM, Lapushin R, Aggarwal BB (1994) Tumor necrosis factor and lymphotoxin: Qualitative and quantitative differences in the mediation of early and late cellular response. J Biol Chem 269: 14575-14583.
36. Yu JV, Deruiter SL, Turner DL (2002) RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 99: 6047-6052.
37. He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, et al. (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 95: 2509-2514.
38. Jain N, Sudhakar C, Swarup G (2007) Tumor necrosis factor α-induced caspase-1 gene expression: Role of p73. FEBS Journal 274: 4396-4407.
39. Gupta V, Swarup G (2006) Evidence for a role of transmembrane protein p25 in localization of protein tyrosine phosphatase TC48 to the ER. J Cell Sci 119: 1703-1714.
40. Paliwal P, Radha V, Swarup G (2007) Regulation of p73 by Hck through kinase-dependent and independent mechanisms. BMC Mol Biol 8: 45.