Mutational analysis of familial and sporadic amyotrophic lateral sclerosis with OPTN mutations in Japanese population

Amyotrophic Lateral Sclerosis

Volumn 13, Issue 6, 2012, Pages 562-566

  Naruse, Hiroya ^a   Takahashi, Yuji ^a   Kihira, Tameko ^b   Yoshida, Sohei ^b   Kokubo, Yasumasa ^c   Kuzuhara, Shigeki ^d   Ishiura, Hiroyuki ^a   Amagasa, Masaharu ^e   Murayama, Shigeo ^f   Tsuji, Shoji ^a   Goto, Jun ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KANSAI UNIVERSITY OF HEALTH SCIENCES   (Japan)

^c MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^e Yamagata Tokushukai Hospital   (Japan)

^f TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Genetic analysis; Motor neuron disease; OPTN mutation; V161M

Indexed keywords

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; FAMILIAL AMYOTROPHIC LATERAL SCLEROSIS; FEMALE; GENE; GENE MUTATION; GENETIC EPIDEMIOLOGY; GENETIC VARIABILITY; HETEROZYGOSITY; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; MOLECULAR EPIDEMIOLOGY; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; OPTN GENE; PRIORITY JOURNAL; SPORADIC AMYOTROPHIC LATERAL SCLEROSIS;

AMYOTROPHIC LATERAL SCLEROSIS; ASIAN CONTINENTAL ANCESTRY GROUP; DNA MUTATIONAL ANALYSIS; FAMILY HEALTH; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; METHIONINE; MIDDLE AGED; MUTATION; TRANSCRIPTION FACTOR TFIIIA; VALINE;

EID: 84866123906     PISSN: 17482968     EISSN: 1471180X     Source Type: Journal    
DOI: 10.3109/17482968.2012.684213     Document Type: Article

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