Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target

Neuroscience

Volumn 229, Issue , 2013, Pages 55-70

  Crish, S D ^a,c   Dapper, J D ^a,d   MacNamee, S E ^a,e   Balaram, P ^a,f   Sidorova, T N ^a   Lambert, W S ^a   Calkins, D J ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e UNIVERSITY OF ARIZONA   (United States)

^f VANDERBILT UNIVERSITY   (United States)

Author keywords

Astrocytes; Axonal transport; Brain derived neurotrophic factor; Glaucoma; Neurodegeneration; Superior colliculus

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BDNF GENE; CELL VACUOLE; CONTROLLED STUDY; GLAUCOMA; IN SITU HYBRIDIZATION; MOUSE; NERVE FIBER TRANSPORT; NEUROCHEMISTRY; NONHUMAN; OPTIC NERVE DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; RETINA GANGLION CELL; SUPERIOR COLLICULUS; SYNAPSE;

ANIMALS; ASTROCYTES; AXONAL TRANSPORT; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; GLAUCOMA; MICE; OPTIC NERVE DISEASES; RATS; RETINAL GANGLION CELLS; RNA, MESSENGER; SUPERIOR COLLICULI; SYNAPSES; VISUAL PATHWAYS;

EID: 84870812784     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.10.069     Document Type: Article

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