Dietary umbelliferone attenuates alcohol-induced fatty liver via regulation of PPARα and SREBP-1c in rats

Alcohol

Volumn 48, Issue 7, 2014, Pages 707-715

  Kim, Myung Joo ^a   Sim, Mi Ok ^b   Lee, Hae In ^c   Ham, Ju Ri ^c   Seo, Kwon Il ^c   Lee, Mi Kyung ^c  

^a Suseong College   (South Korea)

^b Korean Traditional Medicine Jangheung   (South Korea)

^c Sunchon National University   (South Korea)

Author keywords

Alcoholic fatty liver; Lipid metabolism; PPAR ; SREBP 1c; Umbelliferone

Indexed keywords

ACETALDEHYDE; ACETYL COENZYME A ACYLTRANSFERASE; ACYL COENZYME A OXIDASE; ALANINE AMINOTRANSFERASE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ASPARTATE AMINOTRANSFERASE; CARNITINE PALMITOYLTRANSFERASE; CYTOCHROME P450 2E1; FAT DROPLET; FATTY ACID SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UMBELLIFERONE; 7-HYDROXYCOUMARIN; ACETALDOIFOSPHAMIDE; ALDH2 PROTEIN, RAT; ANTILIPEMIC AGENT; IFOSFAMIDE; MITOCHONDRIAL PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UMBELLIFERONE DERIVATIVE;

ACETYL COENZYME A ACYLTRANSFERASE GENE; ACYL COENZYME A OXIDASE GENE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOLIC FATTY LIVER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARNITINE PALMITOYLTRANSFERASE GENE; CIDEA GENE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG MECHANISM; DRUG STRUCTURE; DYSLIPIDEMIA; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; FATTY ACID OXIDATION; FATTY ACID SYNTHASE GENE; GENE; GENE EXPRESSION; LIPID STORAGE; LIPOGENESIS; LIVER PROTECTION; LONG CHAIN FATTY ACID COENZYME A LIGASE GENE; MALE; NONHUMAN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA GENE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA GENE; RAT; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C GENE; WEIGHT REDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; DIET SUPPLEMENTATION; DRUG EFFECTS; ENZYMOLOGY; FATTY LIVER, ALCOHOLIC; LIVER; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ANIMALS; CYTOCHROME P-450 CYP2E1; DIETARY SUPPLEMENTS; FATTY LIVER, ALCOHOLIC; HYPOLIPIDEMIC AGENTS; IFOSFAMIDE; LIVER; MALE; MITOCHONDRIAL PROTEINS; PPAR ALPHA; RATS; RATS, SPRAGUE-DAWLEY; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UMBELLIFERONES;

EID: 84908030985     PISSN: 07418329     EISSN: 18736823     Source Type: Journal    
DOI: 10.1016/j.alcohol.2014.08.008     Document Type: Article

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