The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat diet-induced non-alcoholic fatty liver disease

Food and Chemical Toxicology

Volumn 60, Issue , 2013, Pages 404-412

  Jung, Ji Hye ^a   Kim, Hyun Sook ^a  

^a Sookmyung Women's University   (South Korea)

Author keywords

Antioxidative activity; Cholesterol accumulation; Insulin resistance; Mice; Non alcoholic fatty liver disease

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; ABC TRANSPORTER A1; ADENOSINE MONOPHOSPHATE KINASE; ADIPONECTIN; BILE ACID; CATALASE; CHOLESTEROL; FATTY ACID; GLUTATHIONE PEROXIDASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; ISOFLAVONE; MESSENGER RNA; NITRATE; SOYBEAN PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BLACK SOYBEAN; CHOLESTEROL DIET; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; INSULIN RESISTANCE; LIPID DIET; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; SOYBEAN;

ANTIOXIDATIVE ACTIVITY; CHOLESTEROL ACCUMULATION; INSULIN RESISTANCE; MICE; NON-ALCOHOLIC FATTY LIVER DISEASE;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BILE ACIDS AND SALTS; BLOOD GLUCOSE; CATALASE; CHOLESTEROL; DIET, HIGH-FAT; EQUOL; FATTY LIVER; HYDROXYMETHYLGLUTARYL COA REDUCTASES; ISOFLAVONES; LIPID METABOLISM; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; NITRIC OXIDE; OXIDATIVE STRESS; PPAR GAMMA; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOYBEANS; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; SUPEROXIDE DISMUTASE; TRANSCRIPTOME; TRIGLYCERIDES;

EID: 84883380107     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.07.048     Document Type: Article

References (39)

1. Ackerman Z., Oron-Herman M., Pappo O., Peleg E., Safadi R., Schmilovitz-Weiss H., Grozovski M. Hepatic effects of rosiglitazone in rats with the metabolic syndrome. Basic Clin. Pharmacol. Toxicol. 2010, 107:663-668.
2. Argentou M., Tiniakos D.G., Karanikolas M., Melachrinou M., Makri M.G., Kittas C., Kalfarentzos F. Adipokine serum levels are related to liver histology in severely obese patients undergoing bariatric surgery. Obes. Surg. 2009, 19(9):1313-1323.
3. Bility M.T., Thompson J.T., Mckee R.H., David R.M., Butala J.H., Vanden Heuvel J.P., Peters J.M. Activation of mouse and human peroxisome proliferator-activated receptors (PPARs) by phthalate monoesters. Toxicol. Sci. 2004, 82(1):170-182.
4. Chaves G.V., Souza D.S., Pereira S.E., Saboya C.J., Peres W.A. Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals. Rev. Assoc. Med. Bras. 2012, 58(3):288-293.
5. Choi I., Kim Y., Park Y., Seog H., Choi H. Anti-obesity activities of fermented soygerm isoflavones by Bifidobacterium breve. BioFactors 2007, 29(2-3):105-112.
6. Dhibi M., Brahmi F., Mnari A., Houas Z., Chargui I., Bchir L., Gazzah N., Alsaif M.A., Hammami M. The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats. Nutr. Metab. (Lond.) 2011, 8(1):65.
7. Edvardsson U., Bergström M., Alexandersson M., Bamberg K., Ljung B., Dahllöf B. Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice. J. Lipid Res. 1999, 40(7):1177-1184.
8. Fabbrini E., Sullivan S., Klein S. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 2010, 51(2):679-689.
9. Gil-Izquierdo A., Penalvo J.L., Gil J.I., Medina S., Horcajada M.N., Lafay S., Silberberg M., Llorach R., Zafrilla P., Garcia-Mora P., Ferreres F. Soy isoflavones and cardiovascular disease epidemiological, clinical and -omics perspectives. Curr. Pharm. Biotechnol. 2012, 13(5):624-631.
10. Hirako S., Kim H.J., Shimizu S., Chiba H., Matsumoto A. Low-dose fish oil consumption prevents hepatic lipid accumulation in high cholesterol diet fed mice. J. Agric. Food. Chem. 2011, 59(24):13353-13359.
11. Iio A., Ohguchi K., Maruyama H., Tazawa S., Araki Y., Ichihara K., Nozawa Y., Ito M. Ethanolic extracts of Brazilian red propolis increase ABCA1 expression and promote cholesterol efflux from THP-1 macrophages. Phytomedicine 2012, 19(5):383-388.
12. Ji A., Wroblewski J.M., Cai L., de Beer M.C., Webb N.R., van der Westhuyzen D.R. Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI. J. Lipid Res. 2012, 53(3):446-455.
13. Kalaiselvan V., Kalaivani M., Vijayakumar A., Sureshkumar K., Venkateskumar K. Current knowledge and future direction of research on soy isoflavones as a therapeutic agents. Pharmacogn. Rev. 2010, 4(8):111-117.
14. Kim J.Y., van de Wall E., Laplante M., Azzara A., Trujillo M.E., Hofmann S.M., Schraw T., Durand J.L., Li H., Li G., Jelicks L.A., Mehler M.F., Hui D.Y., Deshaies Y., Shulman G.I., Schwartz G.J., Scherer P.E. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J. Clin. Invest. 2007, 117(9):2621-2637.
15. Kim M.H., Park J.S., Jung J.W., Byun K.W., Kang K.S., Lee Y.S. Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism. Int. J. Obes. (Lond.) 2011, 35(8):1019-1030.
16. Kitamori K., Naito H., Tamada H., Kobayashi M., Miyazawa D., Yasui Y., Sonoda K., Tsuchikura S., Yasui N., Ikeda K., Moriya T., Yamori Y., Nakajima T. Development of novel rat model for high-fat and high-cholesterol diet-induced steatohepatitis and severe fibrosis progression in SHRSP5/Dmcr. Environ. Health Prev. Med. 2012, 17(3):173-182.
17. Lee Y.M., Choi J.S., Kim M.H., Jung M.H., Lee Y.S., Song J. Effects of dietary genistein on hepatic lipid metabolism and mitochondrial function in mice fed high-fat diets. Nutrition 2006, 22(9):956-964.
18. Leng L., Jiang Z.Q., Ji G.Y. Effects of soybean isoflavone on liver lipid metabolism in nonalcoholic fatty liver rats. Zhonghua Yu Fang Yi Xue Za Zhi 2011, 45(4):335-339.
19. Levis S., Strickman-Stein N., Ganjei-Azar P., Xu P., Doerge D.R., Krischer J. Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial. Arch. Intern. Med. 2011, 171(15):1363-1369.
20. Liu Z.M., Ho S.C., Chen Y.M., Ho Y.P. The effects of isoflavones combined with soy protein on lipid profiles, C-reactive protein and cardiovascular risk among postmenopausal Chinese women. Nutr. Metab. Cardiovasc. Dis. 2012, 22(9):712-719.
21. Long Y.C., Zierath J.R. AMP-activated protein kinase signaling in metabolic regulation. J. Clin. Invest. 2006, 116(7):1776-1783.
22. Lyles B.E., Akinyeke T.O., Moss P.E., Stewart L.V. Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARgamma-dependent and PPARgamma-independent pathways. Cell Cycle 2009, 8(2):268-277.
23. Machado M.V., Coutinho J., Carepa F., Costa A., Proença H., Cortez-Pinto H. How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease. Eur. J. Gastroenterol. Hepatol. 2012.
24. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28(7):412-419.
25. McCarthy E.M., Rinella M.E. The role of diet and nutrient composition in nonalcoholic Fatty liver disease. J. Acad. Nutr. Diet. 2012, 112(3):401-409.
26. Medjakovic S., Mueller M., Jungbauer A. Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR. Nutrients 2010, 2(3):241-279.
27. Morita M., Ishida N., Uchiyama K., Yamaguchi K., Itoh Y., Shichiri M., Yoshida Y., Hagihara Y., Naito Y., Yoshikawa T., Niki E. Fatty liver induced by free radicals and lipid peroxidation. Free Radic. Res. 2012, 46(6):758-765.
28. Nobili V., Parola M., Alisi A., Marra F., Piemonte F., Mombello C., Sutti S., Povero D., Maina V., Novo E., Albano E. Oxidative stress parameters in paediatric non-alcoholic fatty liver disease. Int. J. Mol. Med. 2010, 26(4):471-476.
29. Pasarín M., La Mura V., Gracia-Sancho J., Garcia-Caldero H., Rodriguez-Vilarrupla A., Garcia-Pagan J.C., Bosch J., Abraldes J.G. Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD. PLoS ONE 2012, 7(4):e32785.
30. Reddy J.K., Rao M.S. Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation. Am. J. Physiol. Gastrointest. Liver Physiol. 2006, 290(5):G852-G858.
31. Slavin M., Kenworthy W., Yu L.L. Antioxidant properties, phytochemical composition, and antiproliferative activity of Maryland-grown soybeans with colored seed coats. J. Agric. Food Chem. 2009, 57(23):11174-11185.
32. Tailleux A., Wouters K., Staels B. Roles of PPARs in NAFLD: potential therapeutic targets. Biochim. Biophys. Acta 2012, 1821(5):809-818.
33. Uysal S., Armutcu F., Aydogan T., Akin K., Ikizek M., Yigitoglu M.R. Some inflammatory cytokine levels, iron metabolism and oxidan stress markers in subjects with nonalcoholic steatohepatitis. Clin. Biochem. 2011, 44(17-18):1375-1379.
34. Van Rooyen D.M., Farrell G.C. SREBP-2: a link between insulin resistance, hepatic cholesterol, and inflammation in NASH. J. Gastroenterol. Hepatol. 2011, 26(5):789-792.
35. Wijesekara N., Zhang L.H., Kang M.H., Abraham T., Bhattacharjee A., Warnock G.L., Verchere C.B., Hayden M.R. MiR-33a modulates ABCA1 expression, cholesterol accumulation, and insulin secretion in pancreatic islets. Diabetes 2012, 61(3):653-658.
36. Yang H.Y., Tzeng Y.H., Chai C.Y., Hsieh A.T., Chen J.R., Chang L.S., Yang S.S. Soy protein retards the progression of non-alcoholic steatohepatitis via improvement of insulin resistance and steatosis. Nutrition 2011, 27(9):943-948.
37. Yang H.J., Kwon D.Y., Kim M.J., Kang S., Park S. Meju, unsalted soybeans fermented with Bacillus subtilis and Aspergilus oryzae, potentiates insulinotropic actions and improves hepatic insulin sensitivity in diabetic rats. Nutr. Metab. (Lond.) 2012, 9(1):37.
38. Yu S., Matsusue K., Kashireddy P., Cao W.Q., Yeldandi V., Yeldandi A.V., Rao M.S., Gonzalez F.J., Reddy J.K. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. J. Biol. Chem. 2003, 278(1):498-505.
39. Zhao L., Chen Y., Tang R., Chen Y., Li Q., Gong J., Huang A., Varghese Z., Moorhead J.F., Ruan X.Z. Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis. J. Gastroenterol. Hepatol. 2011, 26(5):875-883.