Long-term adaptation of global transcription and metabolism in the liver of high-fat diet-fed C57BL/6J mice

Molecular Nutrition and Food Research

Volumn 55, Issue SUPPL. 2, 2011, Pages

  Do, Gyeong Min ^a   Oh, Hea Young ^b   Kwon, Eun Young ^a   Cho, Yun Young ^a   Shin, Su Kyung ^a   Park, Hae Jin ^a   Jeon, Seon Min ^a   Kim, Eunjung ^c   Hur, Cheol Goo ^b   Park, Tae Sun ^d   Sung, Mi Kyung ^e   Mcgregor, Robin A ^a   Choi, Myung Sook ^a  

^a Kyungpook National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Catholic University of Daegu   (South Korea)

^d Yonsei University   (South Korea)

^e Sookmyung Women's University   (South Korea)

Author keywords

Diet induced obesity; Insulin resistance; Metabolic profile; Microarray; Transcriptional response

Indexed keywords

ANTIOXIDANT; ENZYME; GLUCOSE; LIPID; TRIACYLGLYCEROL;

ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; C57BL MOUSE; DNA MICROARRAY; FATTY LIVER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GLUCOSE TOLERANCE TEST; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID DIET; LIPID METABOLISM; LIVER; MALE; METABOLISM; MOUSE; OBESITY; PHYSIOLOGY; TIME;

ANIMALS; ANTIOXIDANTS; BODY WEIGHT; DIET, HIGH-FAT; ENZYMES; FATTY LIVER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TOLERANCE TEST; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID METABOLISM; LIPIDS; LIVER; MALE; MICE; MICE, INBRED C57BL; OBESITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TIME FACTORS; TRIGLYCERIDES;

MUS;

EID: 80053233555     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100064     Document Type: Article

References (57)

1. Kopelman, P. G., Obesity as a medical problem. Nature 2000, 404, 635-643.
2. Cummings, D. E., Schwartz, M. W., Genetics and pathophysiology of human obesity. Annu. Rev Med. 2003, 54, 453-471.
3. Guh, D. P., Zhang, W., Bansback, N., Amarsi, Z. et al., The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009, 9, 88.
4. Hertog, M. G., Kromhout, D., Aravanis, C., Blackburn, H. et al., Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study. Arch. Intern. Med. 1995, 155, 381-386.
5. Matsuzawa-Nagata, N., Takamura, T., Ando, H., Nakamura, S. et al., Increased oxidative stress precedes the onset of high-fat diet-induced insulin resistance and obesity. Metab. Clin. Exp. 2008, 57, 1071-1077.
6. Rocha, V. Z., Libby, P., Obesity, inflammation, and atherosclerosis. Nat. Rev. Cardiol. 2009, 6, 399-409.
7. Clark, J. M., Diehl, A. M., Hepatic steatosis and type 2 diabetes mellitus. Curr. Diab. Rep. 2002, 2, 210-215.
8. Grayson, M., Nutrigenomics. Nature 2010, 468, S1.
9. Radonjic, M., de Haan, J. R., van Erk, M. J., van Dijk, K. W. et al., Genome-wide mRNA expression analysis of hepatic adaptation to high-fat diets reveals switch from an inflammatory to steatotic transcriptional program. PLoS One 2009, 4, e6646.
10. Kleemann, R., van Erk, M., Verschuren, L., van den Hoek, A. M. et al., Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance. PLoS One 2010, 5, e8817.
11. Matsuzawa, N., Takamura, T., Kurita, S., Misu, H. et al., Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet. Hepatology 2007, 46, 1392-1403.
12. Fraulob, J. C., Ogg-Diamantino, R., Fernandes-Santos, C., Aguila, M. B. et al., A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL/6 mice fed a high fat diet. J. Clin. Biochem. Nutr. 2010, 46, 212-223.
13. Kim, S., Sohn, I., Ahn, J.-I., Lee, K.-H. et al., Hepatic gene expression profiles in a long-term high-fat diet-induced obesity mouse model. Gene 2004, 340, 99-109.
14. Gregoire, F. M., Zhang, Q., Smith, S. J., Tong, C. et al., Diet-induced obesity and hepatic gene expression alterations in C57BL/6J and ICAM-1-deficient mice. Am. J. Physiol. Endocrinol. Metab. 2002, 282, E703-E713.
15. Bligh, E., Dyer, W., A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959, 37, 911-917.
16. Do, G.-M., Kwon, E.-Y., Kim, E., Kim, H.-S. et al., Hepatic transcription response to high-fat treatment in mice: microarray comparison of individual versus. pooled RNA samples. Biotechnol. J. 2010, 5, 970-973.
17. Hulcher, F. H., Oleson, W. H., Simplified spectrophotometric assay for microsomal 3-hydroxy-3-methylglutaryl CoA reductase by measurement of coenzyme A. J. Lipid Res. 1973, 14, 625-631.
18. Davidson, A. L., Arion, W. J., Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity. Arch. Biochem. Biophys. 1987, 253, 156-167.
19. Alegre, M., Ciudad, C. J., Fillat, C., Guinovart, J. J., Determination of glucose-6-phosphatase activity using the glucose dehydrogenase-coupled reaction. Anal. Biochem. 1988, 173, 185-189.
20. Bentle, L. A., Lardy, H. A., Interaction of anions and divalent metal ions with phosphoenolpyruvate carboxykinase. J. Biol. Chem. 1976, 251, 2916-2921.
21. Carl, M. N., Lakshmanan, M. R., Porter, J. W., Fatty acid synthase from rat liver. Methods Enzymol. 1974, 35, 37-44.
22. Markwell, M. A., McGroarty, E. J., Bieber, L. L., Tolbert, N. E., The subcellular distribution of carnitine acyltransferases in mammalian liver and kidney. A new peroxisomal enzyme. J. Biol. Chem. 1973, 248, 3426-3432.
23. Lazarow, P., Assay of peroxisomal β-oxidation of fatty acids. Methods Enzymol. 1981, 72, 315-319.
24. Ochoa, S., Colowick, S. P., Kaplan, N. O. (Eds), Methods Enzymology, Academic Press, New York 1955, pp. 323-326.
25. Pitkänen, E., Pitkänen, O., Uotila, L., Enzymatic determination of unbound D-mannose in serum. Eur. J. Clin. Chem. Clin. Biochem. 1997, 35, 761-766.
26. Wolfram, S., Raederstorff, D., Wang, Y., Teixeira, S. R. et al., TEAVIGO (epigallocatechin gallate) supplementation prevents obesity in rodents by reducing adipose tissue mass. Ann. Nutr. Metab. 2005, 49, 54-63.
27. Shapiro, D. J., Nordstrom, J. L., Mitschelen, J. J., Rodwell, V. W. et al., Micro assay for 3-hydroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblasts. Biochim. Biophys. Acta. 1974, 370, 369-377.
28. Gillies, P. J., Rathgeb, K. A., Perri, M. A., Robinson, C. S., Regulation of acyl-CoA:cholesterol acyltransferase activity in normal and atherosclerotic rabbit aortas: role of a cholesterol substrate pool. Exp. Mol. Pathol. 1986, 44, 329-339.
29. Marklund, S., Marklund, G., Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974, 47, 469-474.
30. Aebi, H., Bergmeyer, H. (Ed.), Methods of Enzymatic Analysis, Academic Press, New York 1986, pp. 673-684.
31. Paglia, D. E., Valentine, W. N., Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 1967, 70, 158-169.
32. Ohkawa, H., Ohishi, N., Yagi, K., Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979, 95, 351-358.
33. Schmittgen, T. D., Livak, K. J., Analyzing real-time PCR data by the comparative C(T) method. Nat Protocol. 2008, 3, 1101-1108.
34. Smyth, G. K., Bioinformatics and Computational Biology Solutions using R and Bioconductor, Springer, New York 2005, pp. 397-420.
35. Huang, D. W., Sherman, B. T., Lempicki, R. A., Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4, 44-57.
36. Gao, S., He, L., Ding, Y., Liu, G., Mechanisms underlying different responses of plasma triglyceride to high-fat diets in hamsters and mice: roles of hepatic MTP and triglyceride secretion. Biochem. Biophys. Res. Commun. 2010, 398, 619-626.
37. Malhi, H., Gores, G. J., Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease. Semin Liver Dis. 2008, 28, 360-369.
38. Puri, V., Ranjit, S., Konda, S., Nicoloro, S. M. C. et al., Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc. Natl. Acad. Sci. USA. 2008, 105, 7833-7838.
39. Wang, R., Kong, X., Cui, A., Liu, X. et al., Sterol-regulatory-element-binding protein 1c mediates the effect of insulin on the expression of Cidea in mouse hepatocytes. Biochem. J. 2010, 430, 245-254.
40. Eccleston, H. B., Andringa, K. K., Betancourt, A. M., King, A. L. et al., Chronic exposure to a high fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice. Antioxid. Redox Signal. 2010, doi:10.1089/ars.2010.3395.
41. Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M. et al., Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 2004, 114, 1752-1761.
42. Hwa, J. J., Zollman, S., Warden, C. H., Taylor, B. A. et al., Genetic and dietary interactions in the regulation of HMG-CoA reductase gene expression. J. Lipid Res. 1992, 33, 711-725.
43. van der Westhuyzen, D. R., Cai, L., de Beer, M. C., de Beer, F. C., Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I. J. Biol. Chem. 2005, 280, 35890-35895.
44. Khera, A. V., Rader, D. J., Future therapeutic directions in reverse cholesterol transport. Curr. Atheroscler. Rep. 2010, 12, 73-81.
45. Pataky, Z., Makoundou, V., Nilsson, P., Gabriel, R. S. et al., Metabolic normality in overweight and obese subjects. Which parameters? Which risks? Int. J. Obes. 2011, 10.1038/ijo.2010.264.
46. Brøns, C., Jensen, C. B., Storgaard, H., Hiscock, N. J. et al., Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men. J. Physiol. 2009, 587, 2387-2397.
47. Kraegen, E. W., Clark, P. W., Jenkins, A. B., Daley, E. A. et al., Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 1991, 40, 1397-1403.
48. Schattenberg, J. M., Schuchmann, M., Diabetes and apoptosis: liver. Apoptosis 2009, 14, 1459-1471.
49. Valverde, A. M., Burks, D. J., Fabregat, I., Fisher, T. L. et al., Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes. Diabetes 2003, 52, 2239-2248.
50. Saltiel, A. R., Kahn, C. R., Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001, 414, 799-806.
51. Park, J., Rho, H. K., Kim, K. H., Choe, S. S. et al., Overexpression of glucose-6-phosphate dehydrogenase is associated with lipid dysregulation and insulin resistance in obesity. Mol. Cell. Biol. 2005, 25, 5146-5157.
52. Agius, L., Peak, M., Newgard, C. B., Gomez-Foix, A. M. et al., Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis. J. Biol. Chem. 1996, 271, 30479-30486.
53. Zhou, Y., Jiang, L., Rui, L., Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. J. Biol. Chem. 2009, 284, 11152-11159.
54. Ryu, D., Oh, K.-J., Jo, H.-Y., Hedrick, S. et al., TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metab. 2009, 9, 240-251.
55. Chen, Z., Gropler, M. C., Norris, J., Lawrence, J. C. et al., Alterations in hepatic metabolism in fld mice reveal a role for lipin 1 in regulating VLDL-triacylglyceride secretion. Arterioscler. Thromb. Vasc. Biol. 2008, 28, 1738-1744.
56. Teli, M. R., James, O. F., Burt, A. D., Bennett, M. K. et al., The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995, 22, 1714-1719.
57. Langhans, W., Role of the liver in the control of glucose-lipid utilization and body weight. Curr. Opin. Clin. Nutr. Metab. Care 2003, 6, 449-455.