Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1 and AMPK

Life Sciences

Volumn 93, Issue 18-19, 2013, Pages 693-699

  Lee, Hae In ^a   McGregor, Robin A ^b   Choi, Myung Sook ^b   Seo, Kown Il ^a   Jung, Un Ju ^b   Yeo, Jiyoung ^c   Kim, Myung Joo ^d   Lee, Mi Kyung ^a  

^a Sunchon National University   (South Korea)

^b Kyungpook National University   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d Daegu Polytechnic College   (South Korea)

Author keywords

Alcohol; Curcumin; Hepatoprotective activity; High fat diet

Indexed keywords

ADENYLATE KINASE; ALANINE AMINOTRANSFERASE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CURCUMIN; CYTOCHROME P450 2E1; FATTY ACID SYNTHASE; LACTATE DEHYDROGENASE; LEPTIN; PHOSPHATIDATE PHOSPHATASE; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL METABOLISM; ALCOHOLISM; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY LIVER; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIPID PEROXIDATION; LIPID STORAGE; LIVER INJURY; LIVER PROTECTION; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; SUPPLEMENTATION; WESTERN BLOTTING;

ALCOHOL; CURCUMIN; HEPATOPROTECTIVE ACTIVITY; HIGH-FAT DIET;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CURCUMIN; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; LIVER DISEASES, ALCOHOLIC; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED ICR;

MUS;

EID: 84886101376     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.09.014     Document Type: Article

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