Activation of interferon-stimulated genes by g-Ray irradiation independently of the ataxia telangiectasia mutated-p53 pathway

Molecular Cancer Research

Volumn 9, Issue 4, 2011, Pages 476-484

  Sugihara, Takashi ^a   Murano, Hayato ^b   Nakamura, Masako ^b   Ichinohe, Kazuaki ^a   Tanaka, Kimio ^a  

^a INSTITUTE FOR ENVIRONMENTAL SCIENCES   (Japan)

^b Tohoku Environmental Sciences Services Corporation   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA INTERFERON; ATM PROTEIN; INTERFERON; PROTEIN P53; RANTES; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BYSTANDER EFFECT; EMBRYO; GAMMA RADIATION; GENE; GENE ACTIVATION; GENE EXPRESSION; INTERFERON STIMULATED GENE; IRF7 GENE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; CHEMOKINE CCL5; CULTURE MEDIA, CONDITIONED; DNA-BINDING PROTEINS; FIBROBLASTS; GAMMA RAYS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; INTERFERON REGULATORY FACTOR-7; INTERFERON REGULATORY FACTORS; INTERFERON TYPE I; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 79954498937     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-10-0358     Document Type: Article

References (27)

1. Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, et al. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 1998;281:1674-7.
2. Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, et al. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 1998;281:1677-9. (Pubitemid 28435584)
3. Lee JH, Paull TT. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 2007;26:7741-8. (Pubitemid 350242454)
4. Lee JH, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005;308:551-4. (Pubitemid 40570585)
5. Haimovitz-Friedman A, Kan CC, Ehleiter D, Persaud RS, McLoughlin M, Fuks Z, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med 1994;180:525-35. (Pubitemid 24224129)
6. Kolesnick R, Fuks Z. Radiation and ceramide-induced apoptosis. Oncogene 2003;22:5897-906. (Pubitemid 37176710)
7. Chen S, Wang G, Makrigiorgos GM, Price BD. Stable siRNA-mediated silencing of ATM alters the transcriptional profile of HeLa cells. Biochem Biophys Res Commun 2004;317:1037-44. (Pubitemid 38496414)
8. Mothersill C, Seymour C. Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells. Int J Radiat Biol 1997;71:421-7. (Pubitemid 27187398)
9. Matsumoto H, Takahashi A, Ohnishi T. Nitric oxide radicals choreograph a radioadaptive response. Cancer Res 2007;67:8574-9. (Pubitemid 47437432)
10. Matsumoto H, Takahashi A, Ohnishi T. Radiation-induced adaptive responses and bystander effects. Biol Sci Space 2004; 18:247-54.
11. Yang H, Asaad N, Held KD. Medium-mediated intercellular communication is involved in bystander responses of X-ray-irradiated normal human fibroblasts. Oncogene 2005;24:2096-103. (Pubitemid 40516203)
12. Umesako S, Fujisawa K, Iiga S, Mori N, Takahashi M, Hong DP, et al. Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice. Breast Cancer Res 2005;7:164-70.
13. Tsukada T, Tomooka Y, Takai S, Ueda Y, Nishikawa S, Yagi T, et al. Enhanced proliferative potential in culture of cells from p53-deficient mice. Oncogene 1993;8:3313-22. (Pubitemid 23342629)
14. Hickson I, Zhao Y, Richardson CJ, Green SJ, Martin NM, Orr AI, et al. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res 2004;64: 9152-9.
15. Sugihara T, Magae J, Wadhwa R, Kaul SC, Kawakami Y, Matsumoto T, et al. Dose and dose-rate effects of low-dose ionizing radiation on activation of Trp53 in immortalized murine cells. Radiat Res 2004;162:296-307. (Pubitemid 39295430)
16. Sugihara T,Murano H, Tanaka K,Oghiso Y. Inverse dose-rate-effects on the expressions of extra-cellular matrix-related genes in low-dose-rate gamma-ray irradiatedmurinecells.JRadiatRes (Tokyo)2008;49:231-40. (Pubitemid 351744275)
17. Motojima M, Matsusaka T, Kon V, Ichikawa I. Fibrinogen that appears in Bowman's space of proteinuric kidneys in vivo activates podocyte Toll-like receptors 2 and 4 in vitro. Nephron Exp Nephrol 2010;114: e39-47.
18. Smiley ST, King JA, Hancock WW. Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol 2001; 167:2887-94. (Pubitemid 32768923)
19. Marié I, Durbin JE, Levy DE. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7. EMBO J 1998;17:6660-9. (Pubitemid 28521799)
20. David M, Petricoin E III, Benjamin C, Pine R, Weber MJ, Larner AC. Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins. Science 1995;269:1721-3.
21. Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005;434:772-7. (Pubitemid 44739521)
22. Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, et al. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage. J Cell Sci 2005;118:1629-39. (Pubitemid 40691891)
23. Takaoka A, Hayakawa S, Yanai H, Stoiber D, Negishi H, Kikuchi H, et al. Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003;424:516-23. (Pubitemid 36975769)
24. Génin P, Algarté M, Roof P, Lin R, Hiscott J. Regulation of RANTES chemokine gene expression requires cooperativity between NFkappa B and IFN-regulatory factor transcription factors. J Immunol 2000;164:5352-61. (Pubitemid 30305215)
25. Johnston CJ, Williams JP, Okunieff P, Finkelstein JN. Radiationinduced pulmonary fibrosis: examination of chemokine and chemokine receptor families. Radiat Res 2002;157:256-65. (Pubitemid 34263838)
26. Olsnes AM, Motorin D, Ryningen A, Zaritskey AY, Bruserud O. T lymphocyte chemotactic chemokines in acute myelogenous leukemia (AML): local release by native human AML blasts and systemic levels of CXCL10 (IP-10), CCL5 (RANTES) and CCL17 (TARC). Cancer Immunol Immunother 2006;55:830-40.
27. Stankovic T, Kidd AM, Sutcliffe A, McGuire GM, Robinson P, Weber P, et al. ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer. Am J Hum Genet 1998;62:334-45. (Pubitemid 28110776)