Stability study perspective of the effect of freeze-drying using cryoprotectants on the structure of insulin loaded into PLGA nanoparticles

Biomacromolecules

Volumn 15, Issue 10, 2014, Pages 3753-3765

  Fonte, Pedro ^a,b   Soares, Sandra ^b   Sousa, Flávia ^b   Costa, Ana ^b,c   Seabra, Vítor ^b   Reis, Salette ^a   Sarmento, Bruno ^b,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSTITUTO DE INVESTIGAÇÃO E FORMAÇÃO AVANÇADA EM CIÊNCIAS E TECNOLOGIAS DA SAÚDE   (Portugal)

^c INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; COPOLYMERS; DRYING; INSULIN; LOW TEMPERATURE DRYING; NANOPARTICLES; PRINCIPAL COMPONENT ANALYSIS; PROTEINS; STRUCTURAL OPTIMIZATION;

FREEZE-DRYING PROCESS; PLGA NANOPARTICLES; POLY(LACTIC-CO-GLYCOLIC ACID); PROTEIN STABILIZATION; STORAGE CONDITION; STRUCTURAL MODIFICATIONS; STRUCTURAL STABILITIES; STRUCTURAL STABILIZATION;

STABILIZATION;

CRYOPROTECTIVE AGENT; FRUCTOSE; GLUCOSE; INSULIN; NANOCARRIER; POLYGLACTIN; SORBITOL; SUCROSE; TREHALOSE; LACTIC ACID; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANALYTIC METHOD; ARTICLE; DRUG STABILITY; FREEZE DRYING; NANOENCAPSULATION; PARTICLE SIZE; PRINCIPAL COMPONENT ANALYSIS; STORAGE; ZETA POTENTIAL; CHEMISTRY; MEDICINAL CHEMISTRY; PROCEDURES; TRANSMISSION ELECTRON MICROSCOPY;

CHEMISTRY, PHARMACEUTICAL; CRYOPROTECTIVE AGENTS; DRUG STABILITY; FREEZE DRYING; FRUCTOSE; GLUCOSE; INSULIN; LACTIC ACID; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; SUCROSE; TREHALOSE;

EID: 84907968489     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm5010383     Document Type: Article

References (40)

1. Danhier, F.; Ansorena, E.; Silva, J.; Coco, R.; Le Breton, A.; Preat, V. J. Controlled Release 2012, 161, 505-522
2. De Jaeghere, F.; Allemann, E.; Leroux, J.-C.; Stevels, W.; Feijen, J.; Doelker, E.; Gurny, R. Pharm. Res. 1999, 16, 859-866
3. Lemoine, D.; Francois, C.; Kedzierewicz, F.; Preat, V.; Hoffman, M.; Maincent, P. Biomaterials 1996, 17, 2191-2197
4. Arakawa, T.; Prestrelski, S.; Kenney, W.; Carpenter, J. Adv. Drug Delivery Rev. 2001, 46, 307-326
5. Wang, W. Int. J. Pharm. 2000, 203, 1-60
6. Holzer, M.; Vogel, V.; Mäntele, W.; Schwartz, D.; Haase, W.; Langer, K. Eur. J. Pharm. Biopharm. 2009, 72, 428-437
7. Franks, F. Eur. J. Pharm. Biopharm. 1998, 45, 221-229
8. Izutsu, K.-I.; Fujimaki, Y.; Kuwabara, A.; Aoyagi, N. Int. J. Pharm. 2005, 301, 161-169
9. Heller, M.; Carpenter, J.; Randolph, T. Biotechnol. Bioeng. 1999, 63, 166-174
10. Kadoya, S.; Fujii, K.; Izutsu, K.-I.; Yonemochi, E.; Terada, K.; Yomota, C.; T. Kawanishi, T. Int. J. Pharm. 2010, 389, 107-113
11. Fonte, P.; Soares, S.; Costa, A.; Andrade, J.; Seabra, V.; Reis, S.; Sarmento, B. Biomaterials 2012, 2, 329-339
12. Sarmento, B.; Ribeiro, A.; Veiga, F.; Ferreira, D. Biomed. Chromatogr. 2006, 20, 898-903
13. European Medicines Agency. Report CPMP/ICH/2736/99, London, U.K., 2003.
14. Dong, A.; Huang, P.; Caughey, W. Biochemistry 1990, 29, 3303-3308
15. Kendrick, B.; Dong, A.; Allison, S.; Manning, M.; Carpenter, J. J. Pharm. Sci. 1996, 85, 155-158
16. Prestrelski, S.; Tedeschi, N.; Arakawa, T.; Carpenter, J. Biophys. J. 1993, 65, 661-671
17. Maltesen, M. J.; Bjerreaard, S.; Hovgaard, L.; Havelund, S.; van de Weert, M. J. Pharm. Sci. 2009, 98, 3265-3277
18. Maisuradze, G.; Liwo, A.; Scheraga, H. J. Mol. Biol. 2009, 385, 312-329
19. Jeong, Y. I.; Shim, Y.-H.; Kim, C.; Lim, G. T.; Choi, K. C.; Yoon, C. J. Microencapsulation 2005, 22, 593-601
20. Abdelwahed, W.; Degobert, G.; Stainmesse, S.; Fessi, H. Adv. Drug Delivery Rev. 2006, 58, 1688-1713
21. Matsumoto, S. In Food Hydrocolloids; Nishinari, K.; Doi, E., Eds.; Springer: New York, 1993; Ch. 62, pp 399-408.
22. Franks, F. Biotechnology 1994, 12, 253-256
23. Sahoo, S. K.; Panyam, J.; Prabha, S.; Labhasetwar, V. J. Controlled Release 2002, 82, 105-114
24. Oksanen, C.; Zografi, G. Pharm. Res. 1990, 7, 654-657
25. Sasaki, H.; Kikuchi, J.; Maeda, T.; Kuboniwa, H. PDA J. Pharm. Sci. Technol. 2010, 64, 63-70
26. Tang, X.; Pikal, M. Pharm. Res. 2004, 21, 191-200
27. Sameti, M.; Bohr, G.; Ravi Kumar, M. N. V.; Kneuer, C.; Bakowsky, U.; Nacken, M.; Schmidt, H.; Lehr, C.-M. Int. J. Pharm. 2003, 266, 51-60
28. Takeuchi, H.; Yamamoto, H.; Toyoda, T.; Toyobuku, H.; Hino, T.; Kawashima, Y. Int. J. Pharm. 1998, 164, 103-111
29. Abdelwahed, W.; Degobert, G.; Fessi, H. Eur. J. Pharm. Biopharm. 2006, 63, 87-94
30. Schmitt, E.; Law, D.; Zhang, G. J. Pharm. Sci. 1999, 88, 291-296
31. D'Antonio, J.; Murphy, B.; Manning, M.; Al-Azzam, W. J. Pharm. Sci. 2012, 101, 2025-2033
32. Schersch, K.; Betz, O.; Garidel, P.; Muehlau, S.; Bassarab, S.; Winter, G. J. Pharm. Sci. 2010, 99, 2256-2278
33. Schersch, K.; Betz, O.; Garidel, P.; Muehlau, S.; Bassarab, S.; Winter, G. J. Pharm. Sci. 2012, 101, 2288-2306
34. Schersch, K.; Betz, O.; Garidel, P.; Muehlau, S.; Bassarab, S.; Winter, G. Eur. J. Pharm. Biopharm. 2013, 85, 240-252
35. Griebenow, K.; Klibanov, A. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 10969-10976
36. Griebenow, K.; Klibanov, A. J. Am. Chem. Soc. 1996, 118, 11695-11700
37. van de Weert, M.; Hering, J.; Haris, P. In Methods for Structural Analysis of Protein Pharmaceuticals; Jiskoot, W.; Crommelin, D., Eds.; AAPS Press: Arlington, TX, 2005; pp 133-168.
38. Saez, A.; Guzmán, M.; Molpeceres, J.; Aberturas, M. Eur. J. Pharm. Biopharm. 2000, 50, 379-387
39. van de Weert, M.; Hennink, W.; Jiskoot, W. Pharm. Res. 2000, 17, 1159-1167
40. Li, S.; Patapoff, T.; Overcashier, D.; Hsu, C.; Nguyen, T.; Borchardt, R. J. Pharm. Sci. 1996, 85, 873-877