Effect of cryoprotectants on the porosity and stability of insulin-loaded PLGA nanoparticles after freeze-drying

Biomatter

Volumn 2, Issue 4, 2012, Pages 329-339

  Fonte, Pedro ^a   Soares, Sandra ^a   Costa, Ana ^a   Andrade, José Carlos ^a   Seabra, Vítor ^a   Reis, Salette ^a   Sarmento, Bruno ^a  

^a UNIVERSITY INSTITUTE OF HEALTH SCIENCES IUCS   (Portugal)

Author keywords

cryoprotectants; freeze drying; insulin; nanoparticles; PLGA; porosity; release profile; surface

Indexed keywords

CRYOPROTECTIVE AGENT; INSULIN; LACTIC ACID; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; RECOMBINANT PROTEIN; SURFACTANT;

CHEMISTRY; DRUG DELIVERY SYSTEM; FREEZE DRYING; HUMAN; NANOMEDICINE; POROSITY; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TIME; TRANSMISSION ELECTRON MICROSCOPY;

CRYOPROTECTIVE AGENTS; DRUG DELIVERY SYSTEMS; FREEZE DRYING; HUMANS; INSULIN; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOMEDICINE; NANOPARTICLES; POLYGLYCOLIC ACID; POROSITY; RECOMBINANT PROTEINS; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS; TIME FACTORS;

EID: 84886728300     PISSN: None     EISSN: 21592535     Source Type: Journal    
DOI: 10.4161/biom.23246     Document Type: Article

References (0)