Freeze-drying of proteins with glass-forming oligosaccharide-derived sugar alcohols

International Journal of Pharmaceutics

Volumn 389, Issue 1-2, 2010, Pages 107-113

  Kadoya, Saori ^a   Fujii, Kahori ^a   Izutsu, Ken ichi ^b   Yonemochi, Etsuo ^a   Terada, Katsuhide ^a   Yomota, Chikako ^b   Kawanishi, Toru ^b  

^a TOHO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Amorphous; Excipients; Freeze drying; Glass transition; Stabilization; Sugar alcohol

Indexed keywords

BOVINE SERUM ALBUMIN; LACTATE DEHYDROGENASE; LACTITOL; MALTITOL; MALTOTRIITOL; MANNITOL; OLIGOSACCHARIDE; SORBITOL; SUGAR ALCOHOL; UNCLASSIFIED DRUG; XYLITOL;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; FREEZE DRYING; MICROSCOPY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; TEMPERATURE SENSITIVITY; THERMOSTABILITY;

ANIMALS; CATTLE; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRUG STORAGE; EXCIPIENTS; FREEZE DRYING; L-LACTATE DEHYDROGENASE; MOLECULAR WEIGHT; SERUM ALBUMIN, BOVINE; SUGAR ALCOHOLS; TEMPERATURE; TRANSITION TEMPERATURE;

EID: 77349087065     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.01.027     Document Type: Article

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