Comparability of protein therapeutics: Quantitative comparison of second-derivative amide I infrared spectra

Journal of Pharmaceutical Sciences

Volumn 101, Issue 6, 2012, Pages 2025-2033

  D'Antonio, Jennifer ^a   Murphy, Brian M ^b   Manning, Mark Cornell ^b   Al Azzam, Wasfi A ^c  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b Legacy BioDesign LLC   (United States)

^c GLAXOSMITHKLINE   (United States)

Author keywords

Area overlap; Biopharmaceuticals characterization; Comparability studies; FTIR; Higher order structures; Protein structure; Proteins; Secondary structure; Spectral correlation coefficient; Structure

Indexed keywords

AMIDE;

ALGORITHM; ARTICLE; COMPUTER PROGRAM; HUMAN; INFRARED SPECTROSCOPY; NONHUMAN; PH; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; TEMPERATURE;

EID: 84859777985     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23133     Document Type: Article

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