The histidine transporter SLC15A4 coordinates mTOR-dependent inflammatory responses and pathogenic antibody production

Immunity

Volumn 41, Issue 3, 2014, Pages 375-388

  Kobayashi, Toshihiko ^a   Shimabukuro Demoto, Shiho ^a   Yoshida Sugitani, Reiko ^a   Furuyama Tanaka, Kaori ^a   Karyu, Hitomi ^a   Sugiura, Yuki ^b,c   Shimizu, Yukiko ^a   Hosaka, Toshiaki ^d   Goto, Motohito ^a   Kato, Norihiro ^a   Okamura, Tadashi ^a   Suematsu, Makoto ^b,c   Yokoyama, Shigeyuki ^d   Toyama Sorimachi, Noriko ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AUTOANTIBODY; CARRIER PROTEIN; HISTIDINE; INTERFERON; INTERFERON REGULATORY FACTOR 7; MAMMALIAN TARGET OF RAPAMYCIN; SLC15A4 PROTEIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; ALPHA BETA INTERFERON RECEPTOR; ANTIBODY; IFNAR1 PROTEIN, MOUSE; IMMUNOGLOBULIN G; IRF7 PROTEIN, MOUSE; MEMBRANE PROTEIN; MTOR PROTEIN, MOUSE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SLC15A4 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE; TLR7 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOANTIBODY PRODUCTION; B LYMPHOCYTE; CELL PH; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOMEOSTASIS; INFLAMMATION; LYSOSOME; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN DEPLETION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANTIBODIES; ANTIBODY FORMATION; AUTOANTIBODIES; B-LYMPHOCYTES; CELLS, CULTURED; IMMUNOGLOBULIN G; INFLAMMATION; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9; TOR SERINE-THREONINE KINASES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84907962139     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.08.011     Document Type: Article

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