Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

European Journal of Human Genetics

Volumn 21, Issue 9, 2013, Pages 994-999

  Wang, Chuan ^a   Ahlford, Annika ^a,n   Järvinen, Tiina M ^b,o   Nordmark, Gunnel ^a   Eloranta, Maija Leena ^a   Gunnarsson, Iva ^c   Svenungsson, Elisabet ^c   Padyukov, Leonid ^c   Sturfelt, Gunnar ^d   Jönsen, Andreas ^d   Bengtsson, Anders A ^d   Truedsson, Lennart ^d   Eriksson, Catharina ^e   Rantapää Dahlqvist, Solbritt ^f   Sjöwall, Christopher ^g   Julkunen, Heikki ^h   Criswell, Lindsey A ⁱ   Graham, Robert R ^j   Behrens, Timothy W ^j   Kere, Juha ^b,k,l   Rönnblom, Lars ^a   Syvänen, Ann Christine ^a   Sandling, Johanna K ^a,m   more..

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF HELSINKI   (Finland)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d LUND UNIVERSITY   (Sweden)

^e UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^f UMEÅ UNIVERSITY   (Sweden)

^g LINKÖPING UNIVERSITY   (Sweden)

^h PEIJAS HOSPITAL   (Finland)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j GENENTECH INC   (United States)

^k FOLKHÄLSAN INSTITUTE OF GENETICS   (Finland)

^l KAROLINSKA INSTITUTE   (Sweden)

^m WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

ⁿ STOCKHOLM UNIVERSITY   (Sweden)

^o OHIO STATE UNIVERSITY   (United States)

more..

Author keywords

Asian; Caucasian; genetic association study; systemic lupus erythematosus

Indexed keywords

ETS1 PROTEIN; IKZF1 PROTEIN; LLRC18 PROTEIN; PROTEIN; RASGRP3 PROTEIN; SLC15A4 PROTEIN; TNIP1 PROTEIN; UNCLASSIFIED DRUG; WDFY4 PROTEIN;

ARTICLE; ASIAN; CASE CONTROL STUDY; CAUCASIAN; CHROMOSOME 16P; CHROMOSOME 16P11.2; CHROMOSOME 7Q; CHROMOSOME 7Q11.23; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; EFFECT SIZE; FINLAND; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SWEDEN; SYSTEMIC LUPUS ERYTHEMATOSUS; UNITED STATES;

ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84882453048     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2012.277     Document Type: Article

References (31)

1. Deng Y, Tsao BP: Genetic susceptibility to systemic lupus erythematosus in the genomic era. Nat Rev Rheumatol 2010; 6: 683-692.
2. Kozyrev SV, Abelson AK, Wojcik J et al: Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 211-216.
3. Hom G, Graham RR, Modrek B et al: Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 2008; 358: 900-909.
4. Harley JB, Alarcon-Riquelme ME, Criswell LA et al: Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40: 204-210.
5. Graham RR, Cotsapas C, Davies L et al: Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008; 40: 1059-1061.
6. Chung SA, Taylor KE, Graham RR et al: Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet 2011; 7: e1001323.
7. Gateva V, Sandling JK, Hom G et al: A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet 2009; 41: 1228-1233.
8. Harley IT, Kaufman KM, Langefeld CD, Harley JB, Kelly JA: Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies. Nat Rev Genet 2009; 10: 285-290.
9. Han JW, Zheng HF, Cui Y et al: Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet 2009; 41: 1234-1237.
10. Yang W, Shen N, Ye DQ et al: Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet 2010; 6: e1000841.
11. Cunninghame Graham DS, Morris DL, Bhangale TR et al: Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. PLoS Genet 2011; 7: e1002341.
12. Okada Y, Shimane K, Kochi Y et al: A genome-wide association study identified aff1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese. PLoS Genet 2012; 8: e1002455.
13. Borchers AT, Naguwa SM, Shoenfeld Y, Gershwin ME: The geoepidemiology of systemic lupus erythematosus. Autoimmun Rev 2010; 9: A277-A287.
14. Plenge RM, Seielstad M, Padyukov L et al: TRAF1-C5 as a risk locus for rheumatoid arthritis-a genomewide study. N Engl J Med 2007; 357: 1199-1209.
15. Koskenmies S, Jarvinen TM, Onkamo P et al: Clinical and laboratory characteristics of Finnish lupus erythematosus patients with cutaneous manifestations. Lupus 2008; 17: 337-347.
16. Koskenmies S, Widen E, Kere J, Julkunen H: Familial systemic lupus erythematosus in Finland. J Rheumatol 2001; 28: 758-760.
17. Tan EM, Cohen AS, Fries JF et al: The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-1277.
18. Purcell S, Neale B, Todd-Brown K et al: PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575.
19. Higgins JP, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in metaanalyses. BMJ 2003; 327: 557-560.
20. Magi R, Morris AP: GWAMA: software for genome-wide association meta-analysis. BMC Bioinformatics 2010; 11: 288.
21. Cole P, MacMahon B: Attributable risk percent in case-control studies. Br J Prev Soc Med 1971; 25: 242-244.
22. Danchenko N, Satia JA, Anthony MS: Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. Lupus 2006; 15: 308-318.
23. Zhong H, Li XL, Li M et al: Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population. Arthritis Res Ther 2011; 13: R186.
24. Kawasaki A, Ito S, Furukawa H et al: Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study. Arthritis Res Ther 2010; 12: R174.
25. Sasawatari S, Okamura T, Kasumi E et al: The solute carrier family 15A4 regulates TLR9 and NOD1 functions in the innate immune system and promotes colitis in mice. Gastroenterology 2011; 140: 1513-1525.
26. Yap WH, Yeoh E, Tay A, Brenner S, Venkatesh B: STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells. FEBS Lett 2005; 579: 4470-4478.
27. Jakes RW, Bae SC, Louthrenoo W, Mok CC, Navarra SV, Kwon N: Systematic review of the epidemiology of systemic lupus erythematosus in the Asia-Pacific region: prevalence, incidence, clinical features, and mortality. Arthritis Care Res 2012; 64: 159-168.
28. Nair RP, Duffin KC, Helms C et al: Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 2009; 41: 199-204.
29. Sun LD, Cheng H, Wang ZX et al: Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet 2010; 42: 1005-1009.
30. Allanore Y, Saad M, Dieude P et al: Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet 2011; 7: e1002091.
31. Osio-Salido E, Manapat-Reyes H: Epidemiology of systemic lupus erythematosus in Asia. Lupus 2010; 19: 1365-1373.