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Volumn 188, Issue 8, 2012, Pages 4113-4121

Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CYTOKINE; INTERFERON; INTERFERON RECEPTOR; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 4; LYSINE; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MYELOID DIFFERENTIATION FACTOR 88; PRISTANE; RIBONUCLEOPROTEIN ANTIBODY; SECONDARY LYMPHOID TISSUE CHEMOKINE; SM ANTIBODY; TOLL LIKE RECEPTOR 7;

EID: 84860351105     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103113     Document Type: Article
Times cited : (50)

References (38)
  • 2
    • 0035968246 scopus 로고    scopus 로고
    • Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
    • Barnes, B. J., P. A. Moore, and P. M. Pitha. 2001. Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J. Biol. Chem. 276: 23382-23390.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23382-23390
    • Barnes, B.J.1    Moore, P.A.2    Pitha, P.M.3
  • 6
    • 77953368347 scopus 로고    scopus 로고
    • Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus
    • Savitsky, D. A., H. Yanai, T. Tamura, T. Taniguchi, and K. Honda. 2010. Contribution of IRF5 in B cells to the development of murine SLE-like disease through its transcriptional control of the IgG2a locus. Proc. Natl. Acad. Sci. USA 107: 10154-10159.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 10154-10159
    • Savitsky, D.A.1    Yanai, H.2    Tamura, T.3    Taniguchi, T.4    Honda, K.5
  • 8
    • 20444368020 scopus 로고    scopus 로고
    • Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms: Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function
    • DOI 10.1074/jbc.M500543200
    • Mancl, M. E., G. Hu, N. Sangster-Guity, S. L. Olshalsky, K. Hoops, P. Fitzgerald-Bocarsly, P. M. Pitha, K. Pinder, and B. J. Barnes. 2005. Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function. J. Biol. Chem. 280: 21078-21090. (Pubitemid 40805667)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 21078-21090
    • Mancl, M.E.1    Hu, G.2    Sangster-Guity, N.3    Olshalsky, S.L.4    Hoops, K.5    Fitzgerald-Bocarsly, P.6    Pitha, P.M.7    Pinder, K.8    Barnes, B.J.9
  • 9
    • 75749153301 scopus 로고    scopus 로고
    • Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus
    • Feng, D., R. C. Stone, M. L. Eloranta, N. Sangster-Guity, G. Nordmark, S. Sigurdsson, C. Wang, G. Alm, A. C. Syvanen, L. Ronnblom, and B. J. Barnes. 2010. Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus. Arthritis Rheum. 62: 562-573.
    • (2010) Arthritis Rheum. , vol.62 , pp. 562-573
    • Feng, D.1    Stone, R.C.2    Eloranta, M.L.3    Sangster-Guity, N.4    Nordmark, G.5    Sigurdsson, S.6    Wang, C.7    Alm, G.8    Syvanen, A.C.9    Ronnblom, L.10    Barnes, B.J.11
  • 10
    • 49449104525 scopus 로고    scopus 로고
    • Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients
    • Niewold, T. B., J. A. Kelly, M. H. Flesch, L. R. Espinoza, J. B. Harley, and M. K. Crow. 2008. Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. Arthritis Rheum. 58: 2481-2487.
    • (2008) Arthritis Rheum. , vol.58 , pp. 2481-2487
    • Niewold, T.B.1    Kelly, J.A.2    Flesch, M.H.3    Espinoza, L.R.4    Harley, J.B.5    Crow, M.K.6
  • 11
    • 47249083830 scopus 로고    scopus 로고
    • Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response
    • Paun, A., J. T. Reinert, Z. Jiang, C. Medin, M. Y. Balkhi, K. A. Fitzgerald, and P. M. Pitha. 2008. Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response. J. Biol. Chem. 283: 14295-14308.
    • (2008) J. Biol. Chem. , vol.283 , pp. 14295-14308
    • Paun, A.1    Reinert, J.T.2    Jiang, Z.3    Medin, C.4    Balkhi, M.Y.5    Fitzgerald, K.A.6    Pitha, P.M.7
  • 14
    • 67349120686 scopus 로고    scopus 로고
    • Genetic susceptibility to SLE: New insights from fine mapping and genome-wide association studies
    • Harley, I. T., K. M. Kaufman, C. D. Langefeld, J. B. Harley, and J. A. Kelly. 2009. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies. Nat. Rev. Genet. 10: 285-290.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 285-290
    • Harley, I.T.1    Kaufman, K.M.2    Langefeld, C.D.3    Harley, J.B.4    Kelly, J.A.5
  • 18
    • 3242805826 scopus 로고    scopus 로고
    • Type I IFN protects against murine lupus
    • Hron, J. D., and S. L. Peng. 2004. Type I IFN protects against murine lupus. J. Immunol. 173: 2134-2142. (Pubitemid 38971652)
    • (2004) Journal of Immunology , vol.173 , Issue.3 , pp. 2134-2142
    • Hron, J.D.1    Peng, S.L.2
  • 19
    • 68949183471 scopus 로고    scopus 로고
    • Induction of autoimmunity by pristane and other naturally occurring hydrocarbons
    • Reeves, W. H., P. Y. Lee, J. S. Weinstein, M. Satoh, and L. Lu. 2009. Induction of autoimmunity by pristane and other naturally occurring hydrocarbons. Trends Immunol. 30: 455-464.
    • (2009) Trends Immunol. , vol.30 , pp. 455-464
    • Reeves, W.H.1    Lee, P.Y.2    Weinstein, J.S.3    Satoh, M.4    Lu, L.5
  • 22
    • 0032494191 scopus 로고    scopus 로고
    • Interleukin 6 dependence of anti-DNA antibody production: Evidence for two pathways of autoantibody formation in pristane-induced lupus
    • DOI 10.1084/jem.188.5.985
    • Richards, H. B., M. Satoh, M. Shaw, C. Libert, V. Poli, and W. H. Reeves. 1998. Interleukin 6 dependence of anti-DNA antibody production: evidence for two pathways of autoantibody formation in pristane-induced lupus. J. Exp. Med. 188: 985-990. (Pubitemid 28433425)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.5 , pp. 985-990
    • Richards, H.B.1    Satoh, M.2    Shaw, M.3    Libert, C.4    Poli, V.5    Reeves, W.H.6
  • 27
    • 21844444831 scopus 로고    scopus 로고
    • New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
    • DOI 10.1038/nri1648
    • Hunter, C. A. 2005. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 5: 521-531. (Pubitemid 40961330)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.7 , pp. 521-531
    • Hunter, C.A.1
  • 30
    • 79551508963 scopus 로고    scopus 로고
    • Critical role of IRF-5 in the development of T helper 1 responses to Leishmania donovani infection
    • Paun, A., R. Bankoti, T. Joshi, P. M. Pitha, and S. Stager. 2011. Critical role of IRF-5 in the development of T helper 1 responses to Leishmania donovani infection. PLoS Pathog. 7: e1001246.
    • (2011) PLoS Pathog. , vol.7
    • Paun, A.1    Bankoti, R.2    Joshi, T.3    Pitha, P.M.4    Stager, S.5
  • 31
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • DOI 10.1038/nri933
    • Sacks, D., and N. Noben-Trauth. 2002. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2: 845-858. (Pubitemid 37328707)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.11 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 33
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow, L. R., D. B. Rosen, N. Brdickova, Y. Xu, J. An, L. L. Lanier, J. G. Cyster, and M. Matloubian. 2006. CD69 acts downstream of interferon-alpha/ beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 440: 540-544.
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1    Rosen, D.B.2    Brdickova, N.3    Xu, Y.4    An, J.5    Lanier, L.L.6    Cyster, J.G.7    Matloubian, M.8
  • 34
    • 79953177480 scopus 로고    scopus 로고
    • CCR7 essentially contributes to the homing of plasmacytoid dendritic cells to lymph nodes under steady-state as well as inflammatory conditions
    • Seth, S., L. Oberdorfer, R. Hyde, K. Hoff, V. Thies, T. Worbs, S. Schmitz, and R. Forster. 2011. CCR7 essentially contributes to the homing of plasmacytoid dendritic cells to lymph nodes under steady-state as well as inflammatory conditions. J. Immunol. 186: 3364-3372.
    • (2011) J. Immunol. , vol.186 , pp. 3364-3372
    • Seth, S.1    Oberdorfer, L.2    Hyde, R.3    Hoff, K.4    Thies, V.5    Worbs, T.6    Schmitz, S.7    Forster, R.8
  • 35
    • 84863115400 scopus 로고    scopus 로고
    • IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus
    • Niewold, T. B., J. A. Kelly, S. N. Kariuki, B. S. Franek, A. A. Kumar, K. M. Kaufman, K. Thomas, D. Walker, S. Kamp, J. M. Frost, et al. 2011. IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus. Ann. Rheum. Dis. 71: 463-469.
    • (2011) Ann. Rheum. Dis. , vol.71 , pp. 463-469
    • Niewold, T.B.1    Kelly, J.A.2    Kariuki, S.N.3    Franek, B.S.4    Kumar, A.A.5    Kaufman, K.M.6    Thomas, K.7    Walker, D.8    Kamp, S.9    Frost, J.M.10
  • 36
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • DOI 10.1038/nri1900, PII NRI1900
    • Honda, K., and T. Taniguchi. 2006. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 6: 644-658. (Pubitemid 44298214)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.9 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 37
    • 0033081259 scopus 로고    scopus 로고
    • Type I interferons keep activated T cells alive
    • Marrack, P., J. Kappler, and T. Mitchell. 1999. Type I interferons keep activated T cells alive. J. Exp. Med. 189: 521-530.
    • (1999) J. Exp. Med. , vol.189 , pp. 521-530
    • Marrack, P.1    Kappler, J.2    Mitchell, T.3
  • 38
    • 0035182394 scopus 로고    scopus 로고
    • Interferon-γ is required for lupus nephritis in mice treated with the hydrocarbon oil pristane
    • DOI 10.1046/j.1523-1755.2001.00045.x
    • Richards, H. B., M. Satoh, J. C. Jennette, B. P. Croker, H. Yoshida, and W. H. Reeves. 2001. Interferon-gamma is required for lupus nephritis in mice treated with the hydrocarbon oil pristane. Kidney Int. 60: 2173-2180. (Pubitemid 33070460)
    • (2001) Kidney International , vol.60 , Issue.6 , pp. 2173-2180
    • Richards, H.B.1    Satoh, M.2    Jennette, J.C.3    Croker, B.P.4    Yoshida, H.5    Reeves, W.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.