Upregulation of SK3 and IK1 channels contributes to the enhanced endothelial calcium signaling and the preserved coronary relaxation in obese Zucker rats

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Climent, Belén ^a   Moreno, Laura ^b   Martínez, Pilar ^b   Contreras, Cristina ^a   Sánchez, Ana ^a   Pérez Vizcaíno, Francisco ^b   García Sacristán, Albino ^a   Rivera, Luis ^a   Prieto, Dolores ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; IK1 PROTEIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; NITROUS OXIDE; NS 309; POTASSIUM CHANNEL STIMULATING AGENT; SK3 PROTEIN; SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; UNCLASSIFIED DRUG; 6,7-DICHLORO-1H-INDOLE-2,3-DIONE 3-OXIME; INDOLE DERIVATIVE; OXIME; SK3 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; FLUORESCENCE ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; MYOGRAPHY; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UPREGULATION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING; ZUCKER RAT; AGONISTS; ANIMAL; CORONARY BLOOD VESSEL; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; VASODILATATION;

RATTUS;

ANIMALS; CALCIUM SIGNALING; CORONARY VESSELS; ENDOTHELIUM, VASCULAR; INDOLES; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MALE; MYOGRAPHY; OBESITY; OXIMES; RATS; RATS, ZUCKER; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; UP-REGULATION; VASODILATION;

EID: 84907814490     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109432     Document Type: Article

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