Endothelium-independent vasorelaxation by the selective alpha estrogen receptor agonist propyl pyrazole triol in rat aortic smooth muscle

Journal of Pharmacy and Pharmacology

Volumn 61, Issue 5, 2009, Pages 641-646

  Alda, José O ^a   Valero, Marta S ^a   Pereboom, Desiree ^a   Gros, Pilar ^a   Garay, Ricardo P ^b  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Estrogen; PPT; Protein kinase G; Rat aorta; Smooth muscle

Indexed keywords

1 [(2 CHLOROPHENYL)DIPHENYLMETHYL] 1H PYRAZOLE; 1,3,5 TRIS(4 HYDROXYPHENYL) 4 PROPYLPYRAZOLE; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 8 BROMO CYCLIC GMP; CALCIUM; CYCLIC GMP; IBERIOTOXIN; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; METHYLPIPERIDINOPYRAZOLE; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL BLOCKING AGENT; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; CELL RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP DEPENDENT PROTEIN KINASE; ESTROGEN RECEPTOR ALPHA; GUANYLATE CYCLASE; POTASSIUM CHANNEL; SOLUBLE GUANYLYL CYCLASE; VASODILATOR AGENT;

ANIMAL TISSUE; AORTA MEDIA; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; CYTOSOL; DRUG SELECTIVITY; MALE; NONHUMAN; RAT; RECEPTOR UPREGULATION; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION; ANIMAL; CHANNEL GATING; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; AORTA, THORACIC; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ESTROGEN RECEPTOR ALPHA; GUANYLATE CYCLASE; ION CHANNEL GATING; MALE; MUSCLE, SMOOTH, VASCULAR; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PYRAZOLES; RATS; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; VASODILATION; VASODILATOR AGENTS;

EID: 85047682932     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp.61.05.0013     Document Type: Article

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