Cellular target of voltage and calcium-dependent K+ channel blockers involved in EDHF-mediated responses in rat superior mesenteric artery

British Journal of Pharmacology

Volumn 134, Issue 5, 2001, Pages 1021-1028

  Ghisdal, P ^a   Morel, N ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Acetylcholine; Calcium; EDHF; Endothelial cells; Mesenteric artery; Rat; Relaxation

Indexed keywords

4 AMINOPYRIDINE; ACETYLCHOLINE; APAMIN; CALCIUM; CHARYBDOTOXIN; EGTAZIC ACID; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; PROSTAGLANDIN F2 ALPHA; THAPSIGARGIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL TONE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPERPOLARIZATION; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; SUPERIOR MESENTERIC ARTERY;

EID: 0035159417     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704348     Document Type: Article

References (50)

1. +]; a functional approach to separating EDHF- and EDNO-related mechanisms in perfused rat mesenteric arterial bed
2. Voltage-dependent calcium entry in confluent bovine capillary endothelial cells
3. Epoxyeicosatrienoic acids, potassium channel blockers and endothelium-dependent hyperpolarization in the guinea-pig carotid artery
4. Some electrical properties of the endothelium-dependent hyperpolarization recorded from rat arterial smooth muscle cells
5. Calcium dependence of the endothelium-dependent hyperpolarization in smooth muscle cells of the rabbit carotid artery
6. Characterization of acetylcholine-induced membrane hyperpolarization in endothelial cells
7. Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig
8. + channels contribute to vascular tone
9. + current in capillary endothelial cells isolated from guinea pig heart
10. + in the rat isolated mesenteric artery
11. Charybdotoxin and apamin block EDHF in rat mesenteric artery if selectively applied to the endothelium
12. Potassium does not mimic EDHF in rat mesenteric arteries
13. Blockade of chloride channels reveals relaxation of rat small mesenteric arteries to raised potassium
14. + is an endothelium-derived hyperpolarizing factor in rat arteries
15. Endothelium-dependent relaxation and hyperpolarization in guinea-pig coronary artery: Role of epoxyeicosatrienoic acid
16. Endothelium-dependent hyperpolarization of canine coronary smooth muscle
17. The third pathway: Endothelium-depcndent hyperpolarization
18. Thapsigargin- and cyclopiazonic acid-induced endothelium-dependent hyperpolarization in rat mesenteric artery
19. 2+ in relation to generation of acetylcholinc-induced endothelium-dependent hyperpolarization in rat mesenteric artery
20. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
21. Effect of nitro-L-arginine on electrical and mechanical responses to acetylcholine in the superior mesenteric artery from stroke-prone hypertensive rat
22. + channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines
23. - currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis
24. Intracellular calcium, currents, and stimulus-response coupling in endothelial cells
25. + current profile
26. 2+-ATPase of the mammalian sarcoplasmic reticulum
27. 2+ concentration in agonist-activated endothelial cells
28. 2+ and ecNOS activity
29. Activators of potassium channels enhance calcium influx into endothelial cells as a consequence of potassium currents
30. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticalum Ca-ATPase family of calcium pumps
31. Calcium-activated potassium channels in the endothelium of intact rat aorta
32. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin
33. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats
34. Permeation properties of a non-selective cation channel in human vascular endothelial cells
35. Ion channels in vascular endothelium
36. Acetylcholine-induced membrane potential changes in endothelial cells of rabbit aortic valve
37. + channels and ouabain-sensitive mechanisms to the endothelium-dependent relaxations of horse penile small arteries
38. Potassium ions and endothelium-derived hyperpolarizing factor in guinea-pig carotid and porcine coronary arteries
39. Role of endothelial cell hyperpolarization in EDHF-mediated responses in the guinea-pig carotid artery
40. + channels
41. Voltage-activated potassium, but not calcium currents in cultured bovine aortic endothelial cells
42. Endothelium-derived hyperpolarizing factor: A new endogenous inhibitor from the vascular endothelium
43. Effect of potassium channel blockers on the L-NAME insensitive relaxations in rat small mesenteric artery
44. Contribution of both nitric oxide and a change in membrane potential to acetylcholine-induced relaxation in the rat small mesenteric artery
45. 2+ entry in endothelial cells
46. 2+ release is dependent on the cytoplasmic concentration of monovalent cations
47. Potentiation of acetylcholine-induced responses in freshly isolated rabbit aortic endothelial cells
48. + channel genes in mesenteric artery smooth muscle cells
49. Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery
50. Involvement of voltage-dependent potassium channels in the EDHF-mediated relaxation of rat hepatic artery